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CYB561D2 Gene

protein-coding   GIFtS: 50
GCID: GC03P050388

Cytochrome B561 Family, Member D2

(Previous name: cytochrome b-561 domain containing 2)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Cytochrome B561 Family, Member D21 2     Putative Tumor Suppressor 101F61
101F62 3 5     TSP102
Putative Tumor Suppressor Protein 101F62 3     XXcos-LUCA11.42
Cytochrome B-561 Domain Containing 21     Cytochrome B561 Domain-Containing Protein 22

External Ids:    HGNC: 302531   Entrez Gene: 110682   Ensembl: ENSG000001143957   OMIM: 6070685   UniProtKB: O145693   
ORGUL members:         

Export aliases for CYB561D2 gene to outside databases

Previous GC identifers: GC03P050348 GC03P050363


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CYB561D2 Gene:
CYB561D2 (cytochrome b561 family, member D2) is a protein-coding gene. Diseases associated with CYB561D2 include lung cancer. An important paralog of this gene is ENSG00000272104.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CYB561D2 gene promoter:
         AP-1   ATF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CYB561D2 promoter sequence
   Search Chromatin IP Primers for CYB561D2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CYB561D2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

CYB561D2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYB561D2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P050388:  view genomic region     (about GC identifiers)

Start:
50,388,126 bp from pter      End:
50,395,891 bp from pter
Size:
7,766 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: C56D2_HUMAN, O14569 (See protein sequence)
Recommended Name: Cytochrome b561 domain-containing protein 2  
Size: 222 amino acids; 23974 Da
Cofactor: Binds 2 heme groups non-covalently (By similarity)
Secondary accessions: A8K552

Explore the universe of human proteins at neXtProt for CYB561D2: NX_O14569

Explore proteomics data for CYB561D2 at MOPED


See CYB561D2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001278213.1  NP_008953.1  

ENSEMBL proteins: 
 ENSP00000400454   ENSP00000410663   ENSP00000232508   ENSP00000391209  

CYB561D2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
CYB: Cytochrome b genes

2 InterPro protein domains:
 IPR004877 Cyt_b561_euk
 IPR006593 Cyt_b561/ferric_Rdtase_TM

Graphical View of Domain Structure for InterPro Entry O14569

ProtoNet protein and cluster: O14569

UniProtKB/Swiss-Prot: C56D2_HUMAN, O14569
Similarity: Contains 1 cytochrome b561 domain


CYB561D2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0046872metal ion binding IEA--
     
CYB561D2 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for CYB561D2:
 Decreased Salmonella enterica  

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CYB561D2
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CYB561D2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CYB561D2

miRNA
Products:
    
miRTarBase miRNAs that target CYB561D2:
hsa-mir-26b-5p (MIRT028765)

Block miRNA regulation of human, mouse, rat CYB561D2 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate CYB561D2:
hsa-miR-1827
SwitchGear 3'UTR luciferase reporter plasmidCYB561D2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CYB561D2
Predesigned siRNA for gene silencing in human, mouse, rat CYB561D2

Gene Editing
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Clone
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OriGene clones in human, mouse for CYB561D2 (see all 6)
OriGene ORF clones in mouse, rat for CYB561D2
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GenScript: all cDNA clones in your preferred vector: CYB561D2 (NM_007022)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYB561D2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB561D2

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB561D2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
C56D2_HUMAN, O14569: Membrane; Multi-pass membrane protein (Probable)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3
cytoskeleton1
cytosol1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--

CYB561D2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CYB561D2
Interactions:

    Search GeneGlobe Interaction Network for CYB561D2

1 Interacting protein for CYB561D2 (O145692, 3) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
UNC119Q134322, 3MINT-63064 I2D: score=4 
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0055114oxidation-reduction process IEA--

CYB561D2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CYB561D2 (C56D2)

1 HMDB Compound for CYB561D2    About this table
CompoundSynonyms CAS #PubMed Ids
Heme(protoporphyrinato)iron (see all 19)14875-96-8--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CYB561D2 gene (2 alternative transcripts): 
NM_001291284.1  NM_007022.4  

Unigene Cluster for CYB561D2:

Cytochrome b561 family, member D2
Hs.149443  [show with all ESTs]
Unigene Representative Sequence: BX641103
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000425346(uc003dam.3) ENST00000424512 ENST00000232508(uc003dal.3)
ENST00000418577 ENST00000419046 ENST00000490926
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CYB561D2 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate CYB561D2:
hsa-miR-1827
SwitchGear 3'UTR luciferase reporter plasmidCYB561D2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CYB561D2
Predesigned siRNA for gene silencing in human, mouse, rat CYB561D2
Clone
Products:
     
OriGene clones in human, mouse for CYB561D2 (see all 6)
OriGene ORF clones in mouse, rat for CYB561D2
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GenScript: all cDNA clones in your preferred vector: CYB561D2 (NM_007022)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYB561D2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB561D2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CYB561D2
OriGene qSTAR qPCR primer pairs in human, mouse for CYB561D2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CYB561D2
  QuantiTect SYBR Green Assays in human, mouse, rat CYB561D2
  QuantiFast Probe-based Assays in human, mouse, rat CYB561D2

Additional mRNA sequence: 

AF040704.1 AK291167.1 BC047691.1 BX641103.1 

14 DOTS entries:

DT.100884971  DT.91774243  DT.100884950  DT.91842030  DT.101985533  DT.121642948  DT.100884948  DT.109213 
DT.91774250  DT.95143048  DT.100884975  DT.120873128  DT.456391  DT.85105475 

Selected AceView cDNA sequences (see all 177):

CK725177 AI738716 CA310735 BE550419 AW051794 AA454950 AI580511 BM829861 
BE857589 CR598666 AA454561 AA235161 AW149205 AF040704 CB142328 CR612474 
CA488481 AA235070 CA503262 AA807710 BQ222076 AI635352 BU179244 BE466017 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CYB561D2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TGTCTGGATG
CYB561D2 Expression
About this image

CYB561D2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CYB561D2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.149443
    Custom PCR Arrays for CYB561D2
Primer
Products:
OriGene qPCR primer pairs and template standards for CYB561D2
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QuantiTect SYBR Green Assays in human, mouse, rat CYB561D2
QuantiFast Probe-based Assays in human, mouse, rat CYB561D2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB561D2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CYB561D2 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cyb561d21 , 5 cytochrome b-561 domain containing 21, 5 89.19(n)1
95.5(a)1
  9 (58.12 cM)5
563681  NM_019720.41  NP_062694.11 
 1075390115 
chicken
(Gallus gallus)
Aves CYB561D21 cytochrome b-561 domain containing 2 75.17(n)
75.51(a)
  100857844  XM_003641969.2  XP_003642017.1 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
76(a)
1 → many
2(150112732-150117495)
African clawed frog
(Xenopus laevis)
Amphibia Xl.324242 Xenopus laevis transcribed sequence with weak similarity to protein refNP_008953.1 (H.sapiens) putative tumor suppressor 101F6; likely ortholog of mouse tumor suppressor, region 10 [Homo sapiens] less 70.86(n)    BJ069764.1 
zebrafish
(Danio rerio)
Actinopterygii cyb561d21 cytochrome b-561 domain containing 2 53.39(n)
52.94(a)
  450082  NM_001006102.1  NP_001006102.1 


ENSEMBL Gene Tree for CYB561D2 (if available)
TreeFam Gene Tree for CYB561D2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CYB561D2 gene
ENSG000002721042  CYB561D12  
1 SIMAP similar gene for CYB561D2 using alignment to 1 protein entry:     C56D2_HUMAN:
CYB561D1

CYB561D2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CYB561D2 (see all 61)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1508014931,2
C,F--50390689(+) ATGACC/TGAGGC 2 T syn12Minor allele frequency- T:0.00NA EU 5875
rs1434241041,2
C--50390723(+) GTTCGC/GTGCTG 2 L V mis11Minor allele frequency- G:0.00NA 4552
rs2012801671,2
C--50390756(+) GAGCAC/TGCTGC 2 R C mis10--------
rs2003559351,2
C--50390804(+) TGCTGA/GGCCTC 2 S G mis10--------
rs1443531081,2
C,F--50390860(+) GTTACG/ACGGCA 2 /T syn11Minor allele frequency- A:0.00NA 4520
rs2010499051,2
C--50390861(+) TTACGC/TGGCAT 2 R W mis10--------
rs1409519301,2
--50390898(+) GTGGG-/CAGGGCT 2 G A fra10--------
rs1435062641,2
C,F--50390926(+) GTGGGG/ACTGCT 2 /G syn11Minor allele frequency- A:0.01NA 4550
rs2008003201,2
--50390947(+) CTGCTA/GCCCCG 2 L syn10--------
rs1442292371,2
C,F--50390951(+) TGCCCC/TGATGG 2 R * stg11Minor allele frequency- T:0.00NA 4550

HapMap Linkage Disequilibrium report for CYB561D2 (50388126 - 50395891 bp)

Structural Variations
     Database of Genomic Variants (DGV) 9 variations for CYB561D2:    About this table    
Variant IDTypeSubtypePubMed ID
dgv5132n71CNV Loss21882294
nsv523662CNV Loss19592680
nsv876770CNV Loss21882294
dgv5131n71CNV Loss21882294
nsv876769CNV Loss21882294
nsv834692CNV Loss17160897
nsv470561CNV Loss18288195
nsv834693CNV Loss17160897
nsv460531CNV Loss19166990

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CYB561D2
DNA2.0 Custom Variant and Variant Library Synthesis for CYB561D2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607068    OMIM disorders: --

1 disease for CYB561D2:    About MalaCards
lung cancer


CYB561D2 for disorders           About GeneDecksing


Export disorders for CYB561D2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CYB561D2 gene, integrated from 10 sources (see all 18):
(articles sorted by number of sources associating them with CYB561D2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. (PubMed id 11085536)1, 2, 3 Lerman M.I. and Minna J.D. (Cancer Res. 2000)
  2. Cytochromes b561: ascorbate-mediated trans-membrane electron transport. (PubMed id 23249217)1, 3 Asard H....BAcrczi A. (amp 2013)
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (Nature 2006)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Dominant-negative cyclin-selective ubiquitin carrier protein E2- C/UbcH10 blocks cells in metaphase. (PubMed id 9122200)1, 3 Townsley F.M.... Ruderman J.V. (Proc. Natl. Acad. Sci. U.S.A. 1997)
  6. Functional expression and characterization of human 101F6 protein, a homologue of cytochrome b561 and a candidate tumor suppressor gene product. (PubMed id 19734123)1, 9 Recuenco M.C....Tsubaki M. (Biofactors 2008)
  7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
  8. Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini. (PubMed id 19892738)2 Xu G.... Jaffrey S.R. (Proc. Natl. Acad. Sci. U.S.A. 2009)
  9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  10. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11068 HGNC: 30253 AceView: CYB561D2 Ensembl:ENSG00000114395 euGenes: HUgn11068
ECgene: CYB561D2 H-InvDB: CYB561D2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CYB561D2 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CYB561D2 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CYB561D2 gene:
Search GeneIP for patents involving CYB561D2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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