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Aliases for CYB561D1 Gene

Aliases for CYB561D1 Gene

  • Cytochrome B561 Family, Member D1 2 3
  • Cytochrome B-561 Domain Containing 1 2

External Ids for CYB561D1 Gene

Summaries for CYB561D1 Gene

GeneCards Summary for CYB561D1 Gene

CYB561D1 (Cytochrome B561 Family, Member D1) is a Protein Coding gene. An important paralog of this gene is ENSG00000272104.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYB561D1 Gene

Genomics for CYB561D1 Gene

Genomic Location for CYB561D1 Gene

Start:
109,494,036 bp from pter
End:
109,502,932 bp from pter
Size:
8,897 bases
Orientation:
Plus strand

Genomic View for CYB561D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CYB561D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYB561D1 Gene

Regulatory Elements for CYB561D1 Gene

Transcription factor binding sites by QIAGEN in the CYB561D1 gene promoter:

Proteins for CYB561D1 Gene

  • Protein details for CYB561D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8Q1-C56D1_HUMAN
    Recommended name:
    Cytochrome b561 domain-containing protein 1
    Protein Accession:
    Q8N8Q1
    Secondary Accessions:
    • B4DH97
    • E9PCM8
    • Q52M36
    • Q5T6C2
    • Q5T6C3

    Protein attributes for CYB561D1 Gene

    Size:
    229 amino acids
    Molecular mass:
    25424 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413; Note=Binds 2 heme groups non-covalently.;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CYB561D1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CYB561D1 Gene

Proteomics data for CYB561D1 Gene at MOPED

Post-translational modifications for CYB561D1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYB561D1 Gene

Domains for CYB561D1 Gene

Gene Families for CYB561D1 Gene

HGNC:
  • CYB :Cytochrome b genes

Protein Domains for CYB561D1 Gene

UniProtKB/Swiss-Prot:

C56D1_HUMAN
Domain:
  • Contains 1 cytochrome b561 domain.:
    • Q8N8Q1
genes like me logo Genes that share domains with CYB561D1: view

Function for CYB561D1 Gene

Gene Ontology (GO) - Molecular Function for CYB561D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with CYB561D1: view

Phenotypes for CYB561D1 Gene

genes like me logo Genes that share phenotypes with CYB561D1: view

miRNA for CYB561D1 Gene

miRTarBase miRNAs that target CYB561D1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CYB561D1 Gene

Localization for CYB561D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYB561D1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CYB561D1 Gene COMPARTMENTS Subcellular localization image for CYB561D1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for CYB561D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CYB561D1: view

Pathways for CYB561D1 Gene

SuperPathways for CYB561D1 Gene

No Data Available

Interacting Proteins for CYB561D1 Gene

Gene Ontology (GO) - Biological Process for CYB561D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYB561D1: view

No data available for Pathways by source for CYB561D1 Gene

Compounds for CYB561D1 Gene

(1) HMDB Compounds for CYB561D1 Gene

Compound Synonyms Cas Number PubMed IDs
Heme
  • (protoporphyrinato)iron
14875-96-8
genes like me logo Genes that share compounds with CYB561D1: view

Transcripts for CYB561D1 Gene

Unigene Clusters for CYB561D1 Gene

Cytochrome b561 family, member D1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CYB561D1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP1: -
SP2:
SP3: - - - -

Relevant External Links for CYB561D1 Gene

GeneLoc Exon Structure for
CYB561D1
ECgene alternative splicing isoforms for
CYB561D1

Expression for CYB561D1 Gene

mRNA expression in normal human tissues for CYB561D1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for CYB561D1 Gene

SOURCE GeneReport for Unigene cluster for CYB561D1 Gene Hs.514682

genes like me logo Genes that share expressions with CYB561D1: view

Orthologs for CYB561D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CYB561D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CYB561D1 36
  • 99.56 (n)
  • 99.56 (a)
CYB561D1 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CYB561D1 36
  • 91.99 (n)
  • 93.45 (a)
CYB561D1 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CYB561D1 36
  • 90.68 (n)
  • 91.7 (a)
CYB561D1 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cyb561d1 36
  • 90.25 (n)
  • 90.39 (a)
Cyb561d1 16
Cyb561d1 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CYB561D1 37
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cyb561d1 36
  • 90.25 (n)
  • 89.52 (a)
lizard
(Anolis carolinensis)
Reptilia CYB561D1 37
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734093 36
  • 61.16 (n)
  • 64.62 (a)
zebrafish
(Danio rerio)
Actinopterygii cyb561d1 36
  • 56.49 (n)
  • 50.44 (a)
cyb561d1 37
  • 44 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3475 37
  • 35 (a)
OneToMany
Species with no ortholog for CYB561D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CYB561D1 Gene

ENSEMBL:
Gene Tree for CYB561D1 (if available)
TreeFam:
Gene Tree for CYB561D1 (if available)

Paralogs for CYB561D1 Gene

Paralogs for CYB561D1 Gene

Selected SIMAP similar genes for CYB561D1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with CYB561D1: view

Variants for CYB561D1 Gene

Sequence variations from dbSNP and Humsavar for CYB561D1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs749056 -- 109,495,216(+) GGTAT(G/T)CCTCA intron-variant
rs1043274 -- 109,499,822(+) CCTCA(C/T)CTTCC utr-variant-3-prime
rs1149171 -- 109,493,840(+) GCCAC(A/G)AAAGT upstream-variant-2KB
rs1278847 -- 109,494,861(-) ttttt(G/T)gttgt intron-variant
rs1278848 -- 109,498,857(-) TTTTT(A/T)AAAAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CYB561D1 Gene

Variant ID Type Subtype PubMed ID
nsv872141 CNV Loss 21882294

Relevant External Links for CYB561D1 Gene

HapMap Linkage Disequilibrium report
CYB561D1

Disorders for CYB561D1 Gene

Relevant External Links for CYB561D1

Genetic Association Database (GAD)
CYB561D1
genes like me logo Genes that share disorders with CYB561D1: view

No data available for UniProtKB/Swiss-Prot for CYB561D1 Gene

Publications for CYB561D1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Genome-wide association study of recurrent early-onset major depressive disorder. (PMID: 20125088) Shi J. … Levinson D.F. (Mol. Psychiatry 2011) 3 49

Products for CYB561D1 Gene

Sources for CYB561D1 Gene

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