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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CYB561 Gene

protein-coding   GIFtS: 55
GCID: GC17M061509

Cytochrome B561

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cytochrome B5611 2     Member A11
Ferric-Chelate Reductase 21 2     CYB561A12
Cytochrome B-5612 3     FRRS22
Cytochrome B561 Family1     Cytochrome B561 Family, Member A12

External Ids:    HGNC: 25711   Entrez Gene: 15342   Ensembl: ENSG000000082837   OMIM: 6000195   UniProtKB: P494473   

Export aliases for CYB561 gene to outside databases

Previous GC identifers: GC17M061161 GC17M063936 GC17M061850 GC17M061983 GC17M058863 GC17M056878


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CYB561 Gene: 
CYB561 (cytochrome b561) is a protein-coding gene. Diseases associated with CYB561 include astrocytoma, and neuroblastoma. GO annotations related to this gene include transmembrane electron transfer carrier and ferric-chelate reductase activity. An important paralog of this gene is CYBRD1.

UniProtKB/Swiss-Prot: CY561_HUMAN, P49447
Function: Secretory vesicle-specific electron transport protein

Gene Wiki entry for CYB561 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CYB561 gene promoter:
         Bach1   Max1   GR   Nkx2-5   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CYB561 promoter sequence
   Search SABiosciences Chromatin IP Primers for CYB561

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYB561


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.3   Ensembl cytogenetic band:  17q23.3   HGNC cytogenetic band: 17q23.3

CYB561 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYB561 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M061509:  view genomic region     (about GC identifiers)

Start:
61,509,665 bp from pter      End:
61,523,739 bp from pter
Size:
14,075 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CY561_HUMAN, P49447 (See protein sequence)
Recommended Name: Cytochrome b561  
Size: 251 amino acids; 27559 Da
Cofactor: Binds 2 heme groups non-covalently (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: B2RE96 D3DU11 Q5BJG9 Q9BU05 Q9BWR9

Explore the universe of human proteins at neXtProt for CYB561: NX_P49447

Explore proteomics data for CYB561 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P49447

  • CYB561 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CYB561 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001017916.1  NP_001017917.1  NP_001906.3  

    ENSEMBL proteins: 
     ENSP00000376701   ENSP00000354028   ENSP00000463162   ENSP00000464470   ENSP00000462325  
     ENSP00000400350   ENSP00000464012   ENSP00000464520   ENSP00000442773   ENSP00000462545  
     ENSP00000464215   ENSP00000462543   ENSP00000464193   ENSP00000463680   ENSP00000376702  

    Human Recombinant Protein Products for CYB561: 
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    Novus Biologicals CYB561 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CYB561 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane NAS7559396

    CYB561 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CYB: Cytochrome b genes

    2 InterPro protein domains:
     IPR004877 Cyt_b561_euk
     IPR006593 Cyt_b561/ferric_Rdtase_TM

    Graphical View of Domain Structure for InterPro Entry P49447

    ProtoNet protein and cluster: P49447

    1 Blocks protein domain: IPB006593 Cytochrome b561 / ferric reductase transmembrane

    UniProtKB/Swiss-Prot: CY561_HUMAN, P49447
    Similarity: Contains 1 cytochrome b561 domain


    CYB561 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CY561_HUMAN, P49447
    Function: Secretory vesicle-specific electron transport protein

         Genatlas biochemistry entry for CYB561:
    cytochrome b561 (30kDaA), specific to catecholamine and neuropeptide secretory vesicles of neuroendocrine tissues

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000293ferric-chelate reductase activity ISS14499595
    GO:0022865transmembrane electron transfer carrier NAS7559396
    GO:0046872metal ion binding IEA--
         
    CYB561 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cyb561):
     behavior/neurological  homeostasis/metabolism  other  skeleton  vision/eye 

    CYB561 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CYB561 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CYB561

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CYB561 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CYB561 

    miRNA
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB561


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYB561

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for CYB561 (P494473 ENSP000003540284) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022900electron transport chain NAS7559396

    CYB561 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CYB561 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CYB561 (CY561)

    1 HMDB Compound for CYB561    About this table
    CompoundSynonyms CAS #PubMed Ids
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--

    9 Novoseek inferred chemical compound relationships for CYB561 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    peptidylglycine 66.5 2 15691328 (1), 7476021 (1)
    ferricyanide 65 4 1849895 (3)
    ascorbic acid 64.4 33 2246231 (8), 1849895 (6), 1962566 (2), 11300772 (1) (see all 13)
    histidine 43.8 2 11300772 (1), 17905810 (1)
    hydroxylamine 37.5 1 2398057 (1)
    catecholamine 31.9 5 18180394 (1), 7980462 (1)
    dopamine 30.4 8 9778036 (1), 9852206 (1), 1785690 (1), 7476021 (1) (see all 5)
    norepinephrine 13.1 1 11532994 (1)
    hydrogen 12.5 2 1849895 (1), 17905810 (1)

    Search CenterWatch for drugs/clinical trials and news about CYB561 / CY561

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CYB561 gene (4 alternative transcripts): 
    NM_001017918.1  NM_001017916.1  NM_001017917.1  NM_001915.3  

    Unigene Cluster for CYB561:

    Cytochrome b561
    Hs.355264  [show with all ESTs]
    Unigene Representative Sequence: AK095244
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000392975(uc002jar.3) ENST00000360793(uc002jap.3 uc002jaq.3 uc002jat.3 uc010wpf.2 uc010wpg.2)
    ENST00000584031(uc002jas.3 uc010ddt.3) ENST00000582297 ENST00000581573
    ENST00000448884 ENST00000585153 ENST00000582034 ENST00000542042 ENST00000580691
    ENST00000581163 ENST00000582997 ENST00000582143 ENST00000584291 ENST00000577989
    ENST00000577368 ENST00000578016 ENST00000578072

    miRNA
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate CYB561 (see all 15):
    hsa-miR-30c hsa-miR-588 hsa-miR-2114 hsa-miR-186* hsa-miR-452* hsa-miR-30d hsa-miR-570 hsa-miR-182
    SwitchGear 3'UTR luciferase reporter plasmidCYB561 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYB561
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYB561
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB561
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    Additional mRNA sequence: 

    AK026598.1 AK095244.1 AK294403.1 AK294630.1 AK301541.1 AK303177.1 AK316606.1 BC000021.1 
    BC002976.1 BC091485.1 BT007096.1 

    24 DOTS entries:

    DT.400224  DT.120919993  DT.100044729  DT.100044730  DT.87016270  DT.100685259  DT.100862436  DT.120920027 
    DT.87014982  DT.92441145  DT.100044731  DT.97862201  DT.92441146  DT.100799536  DT.95227198  DT.120919965 
    DT.120920009  DT.120920026  DT.95227192  DT.100672359  DT.120920029  DT.91803522  DT.92441140  DT.92441143 

    9 AceView cDNA sequences:

    AK095244 BC000021 CR624200 BC002976 NM_001915 BT007096 AK026598 BX648452 
    U06715 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for CYB561 (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11a · 11b ·
    SP1:                                                                    -                 -     -           -                 -     -                           
    SP2:                                      -     -     -     -     -     -                 -     -           -                 -     -                           
    SP3:                                -     -     -     -     -     -     -                 -     -           -                 -     -                           
    SP4:                                      -     -     -     -     -     -                 -     -           -                 -     -                           
    SP5:                                                  -     -     -     -                 -     -                             -     -                           

    ExUns: 11c ^ 12a · 12b · 12c · 12d · 12e · 12f · 12g · 12h · 12i · 12j · 12k ^ 13
    SP1:        -                                                                     
    SP2:        -                                                                     
    SP3:        -                                                                     
    SP4:        -     -     -     -     -     -     -     -     -     -     -         
    SP5:        -                                                                     


    ECgene alternative splicing isoforms for CYB561

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CYB561 expression in normal human tissues (normalized intensities)      CYB561 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGAAAACT
    CYB561 Expression
    About this image


    CYB561 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 15 entries
             Thalamus
             Septum   
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 3 entries
             autonomic/sympathetic/ganglion   
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Blood (Hematopoietic System)
             Peripheral blood-derived hematopoietic stem cells
     
     Spinal Cord (Nervous System)
             Dorsal Horn   

    See CYB561 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CYB561

    SOURCE GeneReport for Unigene cluster: Hs.355264
        SABiosciences Custom PCR Arrays for CYB561
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CYB561 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cyb5611 , 5 cytochrome b-5611, 5 85.02(n)1
    88.66(a)1
      11 (68.81 cM)5
    130561  NM_007805.41  NP_031831.21 
     1059337025 
    chicken
    (Gallus gallus)
    Aves CYB5611 cytochrome b-561 72.56(n)
    67.87(a)
      419952  XM_003642778.1  XP_003642826.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.275482 Xenopus laevis cytochrome B561 (xcyt) mRNA, complete more 71.47(n)    U16364.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cyb5611 cytochrome b-561 61.76(n)
    60.92(a)
      568765  NM_001128744.1  NP_001122216.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG12753 electron transporter 38(a)   62D4   --
    worm
    (Caenorhabditis elegans)
    Secernentea F55H2.53 Cytochrome B561 36(a)   III(9583191-9584501)   --
    rice
    (Oryza sativa)
    Liliopsida Os10g01188001 hypothetical protein 53.27(n)
    41.71(a)
      4347995  NM_001070595.1  NP_001064060.1 


    ENSEMBL Gene Tree for CYB561 (if available)
    TreeFam Gene Tree for CYB561 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CYB561 gene
    CYBRD12  CYB561A32  
    2 SIMAP similar genes for CYB561 using alignment to 11 protein entries:     CY561_HUMAN (see all proteins):
    CYB561A3    CYBRD1

    CYB561 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/343 SNPs in CYB561 are shown (see all 343)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1873148441,2
    --61509195(+) ACAAAC/GCGCAC 3 -- ds50010--------
    rs1493115831,2
    --61509224(+) TTTGCC/GAAAAA 3 -- ds50010--------
    rs99069051,2
    C,H--61509387(+) TCAGGC/TTCTTG 3 -- ds50015Minor allele frequency- T:0.00NS EA WA 510
    rs1436146061,2
    --61509405(+) ACCATC/TCAGGC 3 -- ds50010--------
    rs80724031,2
    C,F--61509422(+) CTCAGG/ACTGAG 3 -- ds50011Minor allele frequency- A:0.05WA 118
    rs1922182641,2
    --61509598(+) CGTCAC/TGTGTC 3 -- ds50010--------
    rs115413861,2
    C--61509721(+) TTCACA/GGAAGA 3 -- ut31 ese32Minor allele frequency- G:0.00NA 4
    rs1479720811,2
    C--61509838(+) ACTTTC/TGTTGC 3 -- ut310--------
    rs1423898571,2
    --61509922(+) AAGGCA/GGAGTT 3 -- ut310--------
    rs775303191,2
    C--61510137(+) GAAATG/TACACT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for CYB561 (61509665 - 61523739 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CYB561:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv908682CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600019    OMIM disorders: --

    2 diseases for CYB561:    About MalaCards
    astrocytoma    neuroblastoma


    CYB561 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): CYB561
    Human Genome Epidemiology (HuGE) Navigator: CYB561 (2 documents)

    Export disorders for CYB561 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CYB561 gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with CYB561)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure and expression of the human gene encoding cytochrome b561, an integral protein of the chromaffin granule membrane. (PubMed id 7559396)1, 2, 9 Srivastava M. (1995)
    2. Human cytochrome b561: a revised hypothesis for conformation in membranes which reconciles sequence and functional information. (PubMed id 7980462)1, 2, 9 Srivastava M.... Fleming P.J. (1994)
    3. Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans. (PubMed id 18180394)1, 4, 9 Fung M.M....O'Connor D.T. (2008)
    4. The human cytochrome b561 gene (CYB561) is located at 17q11-qter. (PubMed id 7959749)1, 3, 9 McBride O.W....Srivastava M. (1994)
    5. Cytochromes b561: Ascorbate-Mediated Trans-Membrane El ectron Transport. (PubMed id 23249217)1, 3 Asard H....Berczi A. (2013)
    6. Nucleotide variations in mitochondrial DNA and supra- physiological ROS levels in cytogenetically normal cases of premature ovarian i nsufficiency. (PubMed id 20680310)1, 4 Kumar M....Dada R. (2010)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1534 HGNC: 2571 AceView: CYB561 Ensembl:ENSG00000008283 euGenes: HUgn1534
    ECgene: CYB561 H-InvDB: CYB561

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CYB561 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CYB561 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CYB561 gene:
    Search GeneIP for patents involving CYB561

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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