Aliases for CXorf65 Gene
External Ids for CXorf65 Gene
- HGNC: 33713
- Entrez Gene: 158830
- Ensembl: ENSG00000204165
- UniProtKB: A6NEN9
Previous GeneCards Identifiers for CXorf65 Gene
- GC0XM070241
- GC0XM070245
- GC0XM070323
- GC0XM064144
Summaries for CXorf65 Gene
GeneCards Summary for CXorf65 Gene
CXorf65 (Chromosome X Open Reading Frame 65) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf65 Gene
Genomics for CXorf65 Gene
Regulatory Elements for CXorf65 Gene
Enhancers for CXorf65 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH0XG071100 | 1.5 | Ensembl ENCODE dbSUPER | 14.7 | -0.6 | -564 | 13.4 | HDGF PKNOX1 ATF1 ARNT WRNIP1 ZFP64 TCF12 ZNF121 ELK1 ZNF207 | MED12 CXorf65 SNX12 IL2RG |
| GH0XG071095 | 1.5 | Ensembl ENCODE dbSUPER | 13.2 | +9.4 | 9370 | 5.0 | CREB3L1 ZNF2 ETS1 TCF12 ZNF121 GLIS2 GATA2 ZNF143 ZNF263 SP3 | MED12 CXorf65 SNX12 IL2RG FOXO4 |
| GH0XG071074 | 0.9 | Ensembl ENCODE | 12.4 | +33.6 | 33587 | 0.4 | RFX1 HLF MAX CEBPB CEBPG EP300 ZNF148 CEBPA STAT3 MAFK | IL2RG MED12 CXorf65 RNU1-56P NUTF2P7 SNX12 GC0XM071059 |
| GH0XG071151 | 0.4 | dbSUPER | 22.1 | -46.2 | -46182 | 3.7 | PRDM4 SPI1 | MED12 CXorf65 IL2RG SNX12 NLGN3 ENSG00000228427 |
| GH0XG071128 | 0.7 | ENCODE | 11.4 | -22.0 | -21999 | 1.9 | CTCF MXI1 RB1 ARID4B MAX RAD21 ZNF143 ZNF207 SMC3 CREM | CXorf65 IL2RG GC0XP071138 MED12 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CXorf65 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CXorf65 gene promoter:
Regulatory Element Products
Genomic Location for CXorf65 Gene
- Chromosome:
- X
- Start:
- 71,103,889 bp from pter
- End:
- 71,106,972 bp from pter
- Size:
- 3,084 bases
- Orientation:
- Minus strand
Genomic View for CXorf65 Gene
Genes around CXorf65 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq13.1 by Ensembl
- Xq13.1 by Entrez Gene
- Xq13.1 by HGNC
CXorf65 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CXorf65 Gene
Proteins for CXorf65 Gene
-
Protein details for CXorf65 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NEN9-CX065_HUMAN
- Recommended name:
- Uncharacterized protein CXorf65
- Protein Accession:
- A6NEN9
Protein attributes for CXorf65 Gene
- Size:
- 183 amino acids
- Molecular mass:
- 21305 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for CXorf65 Gene
Other Protein References for CXorf65 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CXorf65
-
Abcam antibodies for CXorf65
- Invitrogen Antibodies for CXorf65
- Search GeneTex for Antibodies for CXorf65
Protein Products
-
OriGene Purified Proteins for CXorf65
- Search Origene for MassSpec and Protein Over-expression Lysates for CXorf65
- Origene Custom Protein Services for CXorf65
- Novus Biologicals proteins for CXorf65
- Search GeneTex for Proteins for CXorf65
Assay Products
No data available for DME Specific Peptides for CXorf65 Gene
Domains & Families for CXorf65 Gene
Protein Domains for CXorf65 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CXorf65 Gene
Function for CXorf65 Gene
Phenotypes for CXorf65 Gene
- GenomeRNAi human phenotypes for CXorf65:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf65
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf65 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf65 gene
- Search ViGene Biosciences for CXorf65
CRISPR Products
-
OriGene CRISPR knockouts for CXorf65
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf65
- GenScript: Design CRISPR guide RNA sequences for CXorf65
miRNA Products
- Search ViGene Biosciences for CXorf65
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CXorf65
- Browse OriGene Inhibitory RNA Products For CXorf65
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf65 gene
Clone Products
-
OriGene ORF clones in human for CXorf65
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CXorf65
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf65
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CXorf65
-
ViGene Biosciences adenoviral particle packaged cDNA for CXorf65 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf65 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf65 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CXorf65 Gene
Localization for CXorf65 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 2 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf65 Gene
Transcripts for CXorf65 Gene
mRNA/cDNA for CXorf65 Gene
- (2) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (12) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CXorf65 Gene
- Chromosome X open reading frame 65:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CXorf65
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf65
- GenScript: Design CRISPR guide RNA sequences for CXorf65
miRNA Products
- Search ViGene Biosciences for CXorf65
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CXorf65
- Browse OriGene Inhibitory RNA Products For CXorf65
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf65 gene
Clone Products
-
OriGene ORF clones in human for CXorf65
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CXorf65
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf65
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CXorf65 Gene
mRNA differential expression in normal tissues according to GTEx for CXorf65 Gene
This gene is overexpressed in Testis (x19.3), Whole Blood (x14.5), and Spleen (x5.0).
NURSA nuclear receptor signaling pathways regulating expression of CXorf65 Gene:
CXorf65SOURCE GeneReport for Unigene cluster for CXorf65 Gene:
Hs.443936Primer Products
-
OriGene qPCR primer pairs for CXorf65
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf65 Gene
Orthologs for CXorf65 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CXHXorf65 34 |
|
||
| CXorf65 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CXHXorf65 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CXHXorf65 34 |
|
||
| CXorf65 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Gm614 34 16 35 |
|
||
| chicken (Gallus gallus) |
Aves | C4HXorf65 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC570432 34 |
|
||
| CXorf65 35 |
|
OneToOne |
- Species where no ortholog for CXorf65 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CXorf65 Gene
No data available for Paralogs for CXorf65 Gene
Variants for CXorf65 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs111033617 | Pathogenic | 71,108,599(-) | GGAAC(A/G)GTGAG | upstream-variant-2KB, reference, missense | |
| rs137852508 | Pathogenic | 71,108,336(-) | TGCCC(C/T)GAATT | upstream-variant-2KB, reference, stop-gained | |
| rs137852509 | Pathogenic | 71,108,278(-) | CTTTT(A/C)GGTGA | upstream-variant-2KB, reference, stop-gained | |
| rs137852510 | Pathogenic | 71,108,323(-) | CACCC(A/T)GAAGA | upstream-variant-2KB, reference, missense | |
| rs886041333 | Pathogenic | 71,108,276(-) | TTTCG(A/G)TGAGA | upstream-variant-2KB, splice-donor-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1584074 | OTHER | inversion | 17803354 |
| esv33082 | CNV | loss | 17666407 |
Residual Variation Intolerance Score:
88.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.25;
24.98% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CXorf65 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CXorf65
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf65 Gene
Disorders for CXorf65 Gene
Relevant External Links for CXorf65
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CXorf65
No disorders were found for CXorf65 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf65 Gene
Publications for CXorf65 Gene
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
- Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier L.D. … Marra M. (Genome Res. 1996) 3 64
Products for CXorf65 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Immunoprecipitation Assays
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CXorf65
- Search Origene for MassSpec and Protein Over-expression Lysates for CXorf65
- Origene Custom Protein Services for CXorf65
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf65
- Browse OriGene Inhibitory RNA Products For CXorf65
- OriGene qPCR primer pairs for CXorf65
- OriGene CRISPR knockouts for CXorf65
- OriGene ORF clones in human for CXorf65
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for CXorf65 in any vector
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- GenScript: Design CRISPR guide RNA sequences for CXorf65
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- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CXorf65
- Novus Biologicals proteins for CXorf65
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for CXorf65
- ViGene Biosciences adenoviral particle packaged cDNA for CXorf65 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CXorf65 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CXorf65 gene
- Search ViGene Biosciences for CXorf65
- Horizon Cell Lines for CXorf65
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf65
- VectorBuilder custom plasmid, inducible vectors for CXorf65
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf65
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CXorf65 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
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- (125) UMLS
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- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer