CXorf61 Gene
protein-coding GIFtS: 36
GCID: GC0XM115592
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chromosome X open reading frame 61
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Aliases
for CXorf61 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome X Open Reading Frame 611 2 | | KKLC12 5 | | CT831 2 3 | | FLJ206111 | | KK-LC-11 2 3 | | FLJ229131 | | Cancer/Testis Antigen 832 3 | | Kita-Kyushu Lung Cancer Antigen 12 |
Export aliases for CXorf61 gene to outside databasesPrevious GC identifers: GC0XM115507 GC0XM115508 GC0XM105131 |
Summaries
for CXorf61 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CXorf61 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_028405.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CXorf61 gene promoter:
SRF HOXA3 SRF (504 AA) Nkx2-5 Cdc5 Tal-1beta E47 MEF-2A aMEF-2 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for CXorf61
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXorf61 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq23 Ensembl cytogenetic band: Xq23 HGNC cytogenetic band: Xq23CXorf61 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM115592: view genomic region
(about GC identifiers)
Start:
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115,592,849 bp from pter |
End:
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115,594,164 bp from pter |
Size:
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1,316 bases |
Orientation:
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minus strand |
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Proteins
for CXorf61 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KKLC1_HUMAN, Q5H943 (See
protein sequence)Recommended Name: Kita-kyushu lung cancer antigen 1 Size: 113 amino acids; 12784 Da
Subcellular location: Cell membrane; Single-pass type II membrane proteinExplore the universe of human proteins at neXtProt for CXorf61: NX_Q5H943
CXorf61 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001017978.1
ENSEMBL proteins: ENSP00000360961
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
CXorf61 for ontologies About GeneDecksing
CXorf61 Antibody Products:
Assay Products for CXorf61: |
Protein
Domains /
Families
for CXorf61 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5H943 |
Function
for CXorf61 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CXorf61 (NM_001017978) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CXorf61 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf61 |
|
Pathways & Interactions
for CXorf61 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CXorf61
|
Drugs & Compounds
for CXorf61 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CXorf61
Search CenterWatch for drugs/clinical trials and news about CXorf61 / KKLC1
|
Transcripts
for CXorf61 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CXorf61 gene: NM_001017978.3 Unigene Cluster for CXorf61: Chromosome X open reading frame 61 Hs.97892 [show with all ESTs]Unigene Representative Sequence: AK0265661 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000371894(uc004eqj.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CXorf61 (NM_001017978) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CXorf61 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf61 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXorf61
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CXorf61 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CXorf61 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CXorf61 |
Additional cDNA sequence: AK000618.1 AK026566.1 BC062223.1 1 DOTS entry: DT.405569 7 AceView cDNA sequences: BC062223 AA757225 AK026566 AK000618 BQ429641 AA401979 AA412000
GeneLoc Exon Structure
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Expression
for CXorf61 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CXorf61 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACTTCTATT
About this image
See CXorf61 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CXorf61
SOURCE GeneReport for Unigene cluster: Hs.97892
UniProtKB/Swiss-Prot: KKLC1_HUMAN, Q5H943Tissue specificity: Specifically expressed in testis. Expressed by cancer cell lines
SABiosciences Custom PCR Arrays for CXorf61
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXorf61
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CXorf61 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CXorf61 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CXorf61 |
Orthologs
for CXorf61 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for CXorf61 (if available)
TreeFam Gene Tree for CXorf61 (if available) |
Paralogs
for CXorf61 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CXorf61 gene
CXorf61 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CXorf61
PGOHUM00000241509
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Genomic Variants
for CXorf61 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CXorf61 (115592849 - 115594164 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CXorf61: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXorf61 |
|
Disorders
/ Diseases
for CXorf61 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CXorf61 for disorders About GeneDecksing
OMIM gene information: 300625
OMIM disorders: --
3  diseases for CXorf61: About MalaCardslung cancer lung adenocarcinoma adenocarcinoma
Export disorders for CXorf61 gene to outside databases
|
Publications
for CXorf61 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CXorf61 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CXorf61) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a new cancer/germline gene, KK-LC-1, encoding an antigen recognized by autologous CTL induced on human lung adenocarcinoma. (PubMed id 16651449)1, 2, 3 Fukuyama T.... Yasumoto K. (2006)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CXorf61 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing CXorf61 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CXorf61 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CXorf61 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CXorf61 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CXorf61 gene:
Search GeneIP for patents involving CXorf61
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CXorf61 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CXorf61 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CXorf61 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXorf61 | | | OriGene Protein Over-expression Lysate for CXorf61 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CXorf61 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf61 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CXorf61 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CXorf61 | | OriGene Custom Protein Services for CXorf61 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CXorf61 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXorf61 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXorf61 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CXorf61 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CXorf61 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CXorf61 |
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| | | | Search Tocris compounds for CXorf61 |
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 | | | CXorf61 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for CXorf61 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf61 |
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