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Aliases for CXorf58 Gene

Aliases for CXorf58 Gene

  • Chromosome X Open Reading Frame 58 2 3 5

External Ids for CXorf58 Gene

Previous GeneCards Identifiers for CXorf58 Gene

  • GC0XP023835
  • GC0XP021670

Summaries for CXorf58 Gene

GeneCards Summary for CXorf58 Gene

CXorf58 (Chromosome X Open Reading Frame 58) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf58 Gene

Genomics for CXorf58 Gene

Regulatory Elements for CXorf58 Gene

Enhancers for CXorf58 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF023821 0.2 ENCODE 12.7 -85.2 -85200 1.8 SOX13 PKNOX1 ZNF384 FEZF1 ZNF121 ZNF366 PATZ1 PRDM10 KLF8 ZBTB20 APOO CXorf58 PIR60902 GC0XP023785 GC0XP023786
GH0XF024014 0.7 Ensembl ENCODE 12.5 +107.2 107189 0.8 ZNF146 MTA2 ZNF664 ZFHX2 IKZF1 TARDBP PRDM10 ZNF600 EGR2 ZNF18 APOO CXorf58 KLHL15 GC0XP023953
GH0XF024019 0.2 Ensembl 12.1 +111.5 111500 0.2 OSR2 APOO CXorf58 KLHL15 GC0XP023953
GH0XF024020 0.5 Ensembl 12.1 +111.9 111900 0.2 ZNF121 BHLHE40 PRDM1 APOO CXorf58 KLHL15 GC0XP023953
GH0XF023905 0.2 ENCODE 0.8 -0.3 -255 3.3 ATF1 ARID4B SIN3A ZNF48 ZNF2 YY1 GLIS2 ELK1 CBX5 ZNF207 EIF2S3 KLHL15 APOO CXorf58 RPL9P7
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CXorf58 on UCSC Golden Path with GeneCards custom track

Genomic Location for CXorf58 Gene

Chromosome:
X
Start:
23,907,801 bp from pter
End:
23,939,507 bp from pter
Size:
31,707 bases
Orientation:
Plus strand

Genomic View for CXorf58 Gene

Genes around CXorf58 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf58 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf58 Gene

Proteins for CXorf58 Gene

  • Protein details for CXorf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LI9-CX058_HUMAN
    Recommended name:
    Putative uncharacterized protein CXorf58
    Protein Accession:
    Q96LI9

    Protein attributes for CXorf58 Gene

    Size:
    332 amino acids
    Molecular mass:
    38899 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CXorf58 Gene

Post-translational modifications for CXorf58 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CXorf58 Gene

No data available for DME Specific Peptides for CXorf58 Gene

Domains & Families for CXorf58 Gene

Protein Domains for CXorf58 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CXorf58 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf58: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CXorf58 Gene

Function for CXorf58 Gene

genes like me logo Genes that share phenotypes with CXorf58: view

Animal Model Products

miRNA for CXorf58 Gene

miRTarBase miRNAs that target CXorf58

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf58 Gene

Localization for CXorf58 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CXorf58 Gene COMPARTMENTS Subcellular localization image for CXorf58 gene
Compartment Confidence
mitochondrion 2
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf58 Gene

Pathways & Interactions for CXorf58 Gene

SuperPathways for CXorf58 Gene

No Data Available

Interacting Proteins for CXorf58 Gene

Selected Interacting proteins: Q96LI9-CX058_HUMAN for CXorf58 Gene via IID

Symbol External ID(s) Details
GDE1

Gene Ontology (GO) - Biological Process for CXorf58 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CXorf58 Gene

Transcripts for CXorf58 Gene

mRNA/cDNA for CXorf58 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXorf58 Gene

Chromosome X open reading frame 58:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf58 Gene

No ASD Table

Relevant External Links for CXorf58 Gene

GeneLoc Exon Structure for
CXorf58
ECgene alternative splicing isoforms for
CXorf58

Expression for CXorf58 Gene

mRNA expression in normal human tissues for CXorf58 Gene

mRNA differential expression in normal tissues according to GTEx for CXorf58 Gene

This gene is overexpressed in Testis (x24.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CXorf58 Gene



Protein tissue co-expression partners for CXorf58 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CXorf58 Gene:

CXorf58

SOURCE GeneReport for Unigene cluster for CXorf58 Gene:

Hs.351265
genes like me logo Genes that share expression patterns with CXorf58: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CXorf58 Gene

Orthologs for CXorf58 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf58 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia CXHXorf58 34
  • 78.84 (n)
CXorf58 35
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC685700 34
  • 76.89 (n)
cow
(Bos Taurus)
Mammalia CXHXorf58 34
  • 76.63 (n)
MGC165780 35
  • 58 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC102640868 34
  • 72.29 (n)
oppossum
(Monodelphis domestica)
Mammalia CXorf58 35
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CXorf58 35
  • 37 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CXorf58 35
  • 47 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cxorf58 34
  • 58.37 (n)
zebrafish
(Danio rerio)
Actinopterygii CXorf58 35
  • 28 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 37 (a)
OneToOne
Species where no ortholog for CXorf58 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf58 Gene

ENSEMBL:
Gene Tree for CXorf58 (if available)
TreeFam:
Gene Tree for CXorf58 (if available)

Paralogs for CXorf58 Gene

No data available for Paralogs for CXorf58 Gene

Variants for CXorf58 Gene

Sequence variations from dbSNP and Humsavar for CXorf58 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111272439 -- 23,906,250(+) AATTC(C/T)TGTTT intron-variant, upstream-variant-2KB
rs111395689 -- 23,918,504(+) TTGTT(G/T)TTTCT intron-variant
rs111399344 -- 23,935,066(+) CACCA(C/T)GTTGG intron-variant
rs111563534 -- 23,912,758(+) CTCTG(A/G)ATTAA intron-variant
rs111580776 -- 23,926,011(+) CTCGA(A/T)CTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXorf58 Gene

Variant ID Type Subtype PubMed ID
nsv6836 CNV insertion 18451855

Variation tolerance for CXorf58 Gene

Residual Variation Intolerance Score: 91.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.78; 66.70% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CXorf58 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CXorf58

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf58 Gene

Disorders for CXorf58 Gene

Relevant External Links for CXorf58

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CXorf58

No disorders were found for CXorf58 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf58 Gene

Publications for CXorf58 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CXorf58 Gene

Sources for CXorf58 Gene

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