Aliases for CXorf58 Gene
External Ids for CXorf58 Gene
- HGNC: 26356
- Entrez Gene: 254158
- Ensembl: ENSG00000165182
- UniProtKB: Q96LI9
Previous GeneCards Identifiers for CXorf58 Gene
- GC0XP023835
- GC0XP021670
Summaries for CXorf58 Gene
GeneCards Summary for CXorf58 Gene
CXorf58 (Chromosome X Open Reading Frame 58) is a Protein Coding gene. Diseases associated with CXorf58 include Retinitis Pigmentosa 11.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf58 Gene
Genomics for CXorf58 Gene
Regulatory Elements for CXorf58 Gene
Enhancers for CXorf58 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CXorf58 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CXorf58 gene promoter:
Regulatory Element Products
Genomic Location for CXorf58 Gene
- Chromosome:
- X
- Start:
- 23,907,801 bp from pter
- End:
- 23,939,507 bp from pter
- Size:
- 31,707 bases
- Orientation:
- Plus strand
Genomic View for CXorf58 Gene
Genes around CXorf58 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.11 by Ensembl
- Xp22.11 by Entrez Gene
- Xp22.11 by HGNC
CXorf58 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CXorf58 Gene
Proteins for CXorf58 Gene
-
Protein details for CXorf58 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96LI9-CX058_HUMAN
- Recommended name:
- Putative uncharacterized protein CXorf58
- Protein Accession:
- Q96LI9
Protein attributes for CXorf58 Gene
- Size:
- 332 amino acids
- Molecular mass:
- 38899 Da
- Quaternary structure:
- No Data Available
Protein Expression for CXorf58 Gene
Post-translational modifications for CXorf58 Gene
Other Protein References for CXorf58 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CXorf58
-
Abcam antibodies for CXorf58
- Invitrogen Antibodies for CXorf58
- Search GeneTex for Antibodies for CXorf58
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CXorf58
- Origene Custom Protein Services for CXorf58
- Novus Biologicals proteins for CXorf58
- Search GeneTex for Proteins for CXorf58
Assay Products
No data available for DME Specific Peptides for CXorf58 Gene
Domains & Families for CXorf58 Gene
Protein Domains for CXorf58 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for CXorf58 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CXorf58 Gene
Function for CXorf58 Gene
Phenotypes for CXorf58 Gene
- GenomeRNAi human phenotypes for CXorf58:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf58
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf58 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf58 gene
- Search ViGene Biosciences for CXorf58
CRISPR Products
-
OriGene CRISPR knockouts for CXorf58
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf58
- GenScript: Design CRISPR guide RNA sequences for CXorf58
miRNA for CXorf58 Gene
- miRTarBase miRNAs that target CXorf58
miRNA Products
- Search ViGene Biosciences for CXorf58
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CXorf58
- Browse OriGene Inhibitory RNA Products For CXorf58
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf58 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXorf58
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf58
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CXorf58
-
ViGene Biosciences adenoviral particle packaged cDNA for CXorf58 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf58 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf58 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf58 Gene
Localization for CXorf58 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 2 |
| peroxisome | 1 |
| nucleus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf58 Gene
Pathways & Interactions for CXorf58 Gene
No Data Available
Interacting Proteins for CXorf58 Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| GDE1 |
No data available for Pathways by source and SIGNOR curated interactions for CXorf58 Gene
Transcripts for CXorf58 Gene
mRNA/cDNA for CXorf58 Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (8) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CXorf58 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CXorf58
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf58
- GenScript: Design CRISPR guide RNA sequences for CXorf58
miRNA Products
- Search ViGene Biosciences for CXorf58
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CXorf58
- Browse OriGene Inhibitory RNA Products For CXorf58
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf58 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXorf58
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf58
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CXorf58 Gene
mRNA differential expression in normal tissues according to GTEx for CXorf58 Gene
This gene is overexpressed in Testis (x24.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CXorf58 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CXorf58 Gene:
CXorf58SOURCE GeneReport for Unigene cluster for CXorf58 Gene:
Hs.351265Primer Products
-
OriGene qPCR primer pairs for CXorf58
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf58 Gene
Orthologs for CXorf58 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | CXHXorf58 34 |
|
||
| CXorf58 35 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | LOC685700 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CXHXorf58 34 |
|
||
| MGC165780 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | LOC102640868 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CXorf58 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CXorf58 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CXorf58 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cxorf58 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | CXorf58 35 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for CXorf58 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CXorf58 Gene
No data available for Paralogs for CXorf58 Gene
Variants for CXorf58 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000277974 | -- | 23,911,589(+) | GTAGA(-/T)TCTGC | intron-variant | |
| rs1000394046 | -- | 23,929,924(+) | CGGGC(A/G)GAGTG | intron-variant | |
| rs1000451000 | -- | 23,912,465(+) | AGCTC(C/T)GAATC | intron-variant | |
| rs1000880066 | -- | 23,908,802(+) | AGACC(A/G)CTAGG | intron-variant, upstream-variant-2KB | |
| rs1000929118 | -- | 23,912,125(+) | GTTTT(A/G)TATTT | intron-variant |
Residual Variation Intolerance Score:
91.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.78;
66.70% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CXorf58 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CXorf58
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf58 Gene
Disorders for CXorf58 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinitis pigmentosa 11 |
|
|
Search CXorf58 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CXorf58
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CXorf58
No data available for UniProtKB/Swiss-Prot and Genatlas for CXorf58 Gene
Publications for CXorf58 Gene
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for CXorf58 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
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- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CXorf58
- Origene Custom Protein Services for CXorf58
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf58
- Browse OriGene Inhibitory RNA Products For CXorf58
- OriGene qPCR primer pairs for CXorf58
- OriGene CRISPR knockouts for CXorf58
- OriGene ORF clones in human for CXorf58
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for CXorf58 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CXorf58
- GenScript Custom Assay Services for CXorf58
- GenScript Custom overexpressing Cell Line Services for CXorf58
- GenScript: Design CRISPR guide RNA sequences for CXorf58
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
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- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CXorf58
- Novus Biologicals proteins for CXorf58
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for CXorf58 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CXorf58 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CXorf58 gene
- Search ViGene Biosciences for CXorf58
- Horizon Cell Lines for CXorf58
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf58
- VectorBuilder custom plasmid, inducible vectors for CXorf58
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf58
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CXorf58 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer