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Aliases for CXorf57 Gene

Aliases for CXorf57 Gene

  • Chromosome X Open Reading Frame 57 2 3

External Ids for CXorf57 Gene

Previous GeneCards Identifiers for CXorf57 Gene

  • GC0XP105741
  • GC0XP105855
  • GC0XP095482

Summaries for CXorf57 Gene

GeneCards Summary for CXorf57 Gene

CXorf57 (Chromosome X Open Reading Frame 57) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf57 Gene

Genomics for CXorf57 Gene

Regulatory Elements for CXorf57 Gene

Genomic Location for CXorf57 Gene

106,611,930 bp from pter
106,679,443 bp from pter
67,514 bases
Plus strand

Genomic View for CXorf57 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CXorf57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf57 Gene

Proteins for CXorf57 Gene

  • Protein details for CXorf57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein CXorf57
    Protein Accession:
    Secondary Accessions:
    • H7BY89
    • Q4G0L7
    • Q5JQS1
    • Q5JRF9
    • Q6PHY5
    • Q6PII9
    • Q6PJU8
    • Q9H7W5
    • Q9NWA6

    Protein attributes for CXorf57 Gene

    855 amino acids
    Molecular mass:
    97554 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CXorf57 Gene


neXtProt entry for CXorf57 Gene

Proteomics data for CXorf57 Gene at MOPED

Post-translational modifications for CXorf57 Gene

  • Ubiquitination at Lys454, Lys483, Lys624, Lys648, Lys651, Lys689, and Lys817
  • Modification sites at PhosphoSitePlus

Other Protein References for CXorf57 Gene

No data available for DME Specific Peptides for CXorf57 Gene

Domains for CXorf57 Gene

Protein Domains for CXorf57 Gene


Suggested Antigen Peptide Sequences for CXorf57 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf57: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CXorf57 Gene

Function for CXorf57 Gene

Gene Ontology (GO) - Molecular Function for CXorf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with CXorf57: view

Animal Model Products

CRISPR Products

miRNA for CXorf57 Gene

miRTarBase miRNAs that target CXorf57

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CXorf57

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CXorf57 Gene

Localization for CXorf57 Gene

Subcellular locations from

Jensen Localization Image for CXorf57 Gene COMPARTMENTS Subcellular localization image for CXorf57 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf57 Gene

Pathways for CXorf57 Gene

SuperPathways for CXorf57 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CXorf57 Gene


No data available for Pathways by source for CXorf57 Gene

Transcripts for CXorf57 Gene

Unigene Clusters for CXorf57 Gene

Chromosome X open reading frame 57:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CXorf57

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf57 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13a · 13b ^ 14
SP1: - - -
SP2: - - - - -
SP5: -

Relevant External Links for CXorf57 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CXorf57 Gene

mRNA expression in normal human tissues for CXorf57 Gene

mRNA differential expression in normal tissues according to GTEx for CXorf57 Gene

This gene is overexpressed in Brain - Hypothalamus (8.1) and Pituitary (6.6).

Protein differential expression in normal tissues for CXorf57 Gene

This gene is overexpressed in Stomach (17.3), Lung (12.7), Kidney (12.1), Fetal Brain (9.5), and Esophagus (9.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CXorf57 Gene

SOURCE GeneReport for Unigene cluster for CXorf57 Gene Hs.274267

genes like me logo Genes that share expressions with CXorf57: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for CXorf57 Gene

Orthologs for CXorf57 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf57 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CXHXorf57 35
  • 82.96 (n)
  • 76.79 (a)
CXorf57 36
  • 77 (a)
(Canis familiaris)
Mammalia CXHXorf57 35
  • 88.77 (n)
  • 87.95 (a)
CXorf57 36
  • 87 (a)
(Mus musculus)
Mammalia D330045A20Rik 35
  • 82.33 (n)
  • 79.22 (a)
D330045A20Rik 16
D330045A20Rik 36
  • 79 (a)
(Pan troglodytes)
Mammalia CXHXorf57 35
  • 98 (n)
  • 96.91 (a)
CXorf57 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC680663 35
  • 83.49 (n)
  • 80.76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 51 (a)
-- 36
  • 61 (a)
(Gallus gallus)
Aves C4HXORF57 35
  • 59.69 (n)
  • 48.82 (a)
CXorf57 36
  • 43 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
-- 36
  • 36 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100498514 35
  • 55.5 (n)
  • 44.75 (a)
(Danio rerio)
Actinopterygii si:ch211-26b3.2 35
  • 48.13 (n)
  • 37.03 (a)
C5HXorf57 36
  • 33 (a)
Species with no ortholog for CXorf57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf57 Gene

Gene Tree for CXorf57 (if available)
Gene Tree for CXorf57 (if available)

Paralogs for CXorf57 Gene

No data available for Paralogs for CXorf57 Gene

Variants for CXorf57 Gene

Sequence variations from dbSNP and Humsavar for CXorf57 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1346255 -- 106,632,644(+) CTTCG(A/C)GATCC reference, synonymous-codon
rs1365574 -- 106,664,127(+) GAAGC(A/G)CAAAA intron-variant
rs1426860 -- 106,671,648(+) AAGAG(A/T)GCCAC intron-variant
rs1582802 -- 106,657,471(+) TCTCA(A/G)CTTGG intron-variant
rs1582803 -- 106,657,571(+) GATTT(A/G)AAATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXorf57 Gene

Variant ID Type Subtype PubMed ID
esv2752312 CNV Gain 17911159

Relevant External Links for CXorf57 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf57 Gene

Disorders for CXorf57 Gene

No disorders were found for CXorf57 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CXorf57 Gene

Publications for CXorf57 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for CXorf57 Gene

Sources for CXorf57 Gene

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