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Aliases for CXorf56 Gene

Aliases for CXorf56 Gene

  • Chromosome X Open Reading Frame 56 2 3 5

External Ids for CXorf56 Gene

Previous GeneCards Identifiers for CXorf56 Gene

  • GC0XM118556
  • GC0XM118672
  • GC0XM108165

Summaries for CXorf56 Gene

Entrez Gene Summary for CXorf56 Gene

  • While this gene is well-supported by transcript data, no functional information on its protein products is currently available. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

GeneCards Summary for CXorf56 Gene

CXorf56 (Chromosome X Open Reading Frame 56) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf56 Gene

Genomics for CXorf56 Gene

Regulatory Elements for CXorf56 Gene

Enhancers for CXorf56 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CXorf56 on UCSC Golden Path with GeneCards custom track

Promoters for CXorf56 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CXorf56 on UCSC Golden Path with GeneCards custom track

Genomic Location for CXorf56 Gene

Chromosome:
X
Start:
119,538,149 bp from pter
End:
119,565,434 bp from pter
Size:
27,286 bases
Orientation:
Minus strand

Genomic View for CXorf56 Gene

Genes around CXorf56 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf56 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf56 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf56 Gene

Proteins for CXorf56 Gene

  • Protein details for CXorf56 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H5V9-CX056_HUMAN
    Recommended name:
    UPF0428 protein CXorf56
    Protein Accession:
    Q9H5V9
    Secondary Accessions:
    • A8MPX7
    • B4DQN2
    • D3DWH9
    • F5GWL7
    • O43351

    Protein attributes for CXorf56 Gene

    Size:
    222 amino acids
    Molecular mass:
    25625 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB96348.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for CXorf56 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CXorf56 Gene

Proteomics data for CXorf56 Gene at MOPED

Post-translational modifications for CXorf56 Gene

  • Ubiquitination at Lys 67, Lys 121, and Lys 128
  • Modification sites at PhosphoSitePlus

Other Protein References for CXorf56 Gene

No data available for DME Specific Peptides for CXorf56 Gene

Domains & Families for CXorf56 Gene

Protein Domains for CXorf56 Gene

Blocks:
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CXorf56 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H5V9

UniProtKB/Swiss-Prot:

CX056_HUMAN :
  • Belongs to the UPF0428 family.
Family:
  • Belongs to the UPF0428 family.
genes like me logo Genes that share domains with CXorf56: view

No data available for Gene Families for CXorf56 Gene

Function for CXorf56 Gene

Phenotypes for CXorf56 Gene

genes like me logo Genes that share phenotypes with CXorf56: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf56 Gene

Localization for CXorf56 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CXorf56 Gene COMPARTMENTS Subcellular localization image for CXorf56 gene
Compartment Confidence
nucleus 3
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf56 Gene

Pathways & Interactions for CXorf56 Gene

SuperPathways for CXorf56 Gene

No Data Available

Interacting Proteins for CXorf56 Gene

Gene Ontology (GO) - Biological Process for CXorf56 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CXorf56 Gene

Drugs & Compounds for CXorf56 Gene

No Compound Related Data Available

Transcripts for CXorf56 Gene

mRNA/cDNA for CXorf56 Gene

Unigene Clusters for CXorf56 Gene

Chromosome X open reading frame 56:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf56 Gene

No ASD Table

Relevant External Links for CXorf56 Gene

GeneLoc Exon Structure for
CXorf56
ECgene alternative splicing isoforms for
CXorf56

Expression for CXorf56 Gene

mRNA expression in normal human tissues for CXorf56 Gene

Protein differential expression in normal tissues from HIPED for CXorf56 Gene

This gene is overexpressed in Bone (33.7) and Peripheral blood mononuclear cells (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CXorf56 Gene



SOURCE GeneReport for Unigene cluster for CXorf56 Gene Hs.248572

genes like me logo Genes that share expression patterns with CXorf56: view

Protein tissue co-expression partners for CXorf56 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CXorf56 Gene

Orthologs for CXorf56 Gene

This gene was present in the common ancestor of animals.

Orthologs for CXorf56 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CXHXorf56 35
  • 93.39 (n)
  • 99.1 (a)
CXorf56 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CXHXorf56 35
  • 92.34 (n)
  • 100 (a)
CXorf56 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C330007P06Rik 35
  • 92.04 (n)
  • 99.55 (a)
C330007P06Rik 16
C330007P06Rik 36
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CXHXorf56 35
  • 96.49 (n)
  • 94.74 (a)
-- 36
  • 96 (a)
OneToMany
-- 36
  • 100 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1564541 35
  • 91.89 (n)
  • 99.55 (a)
oppossum
(Monodelphis domestica)
Mammalia CXorf56 36
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CXorf56 36
  • 93 (a)
OneToOne
chicken
(Gallus gallus)
Aves CXORF56 35
  • 82.85 (n)
  • 95.67 (a)
CXorf56 36
  • 95 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cxorf56 35
  • 79.13 (n)
  • 91.44 (a)
MGC76077 35
African clawed frog
(Xenopus laevis)
Amphibia c330007p06-A-prov 35
zebrafish
(Danio rerio)
Actinopterygii Dr.17887 35
zgc:103697 35
  • 77.63 (n)
  • 88.74 (a)
C5HXorf56 36
  • 88 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2208 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005769 35
  • 59.31 (n)
  • 61.03 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG16865 35
  • 58.46 (n)
  • 57.07 (a)
CG16865 36
  • 47 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y66D12A.8 35
  • 52.33 (n)
  • 43.02 (a)
Y66D12A.8 36
  • 36 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.6041 35
Species with no ortholog for CXorf56:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CXorf56 Gene

ENSEMBL:
Gene Tree for CXorf56 (if available)
TreeFam:
Gene Tree for CXorf56 (if available)

Paralogs for CXorf56 Gene

No data available for Paralogs for CXorf56 Gene

Variants for CXorf56 Gene

Sequence variations from dbSNP and Humsavar for CXorf56 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747710846 -- 119,549,398(+) ATTGA(C/T)AGAAG intron-variant
rs747711330 -- 119,558,120(+) GCCAG(A/C)CTGGT intron-variant
rs747761730 -- 119,559,644(+) CATCT(A/T)CACAG intron-variant
rs747778976 -- 119,542,136(+) ATCTC(A/G)GTTCA intron-variant
rs747804102 -- 119,540,290(+) CAATT(C/T)ATTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXorf56 Gene

Variant ID Type Subtype PubMed ID
nsv525652 CNV Gain 19592680

Variation tolerance for CXorf56 Gene

Residual Variation Intolerance Score: 42.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.11; 2.42% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CXorf56 Gene

Disorders for CXorf56 Gene

Relevant External Links for CXorf56

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CXorf56

No disorders were found for CXorf56 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf56 Gene

Publications for CXorf56 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Dynamic protein-protein interaction wiring of the human spliceosome. (PMID: 22365833) Hegele A. … Stelzl U. (Mol. Cell 2012) 3

Products for CXorf56 Gene

Sources for CXorf56 Gene

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