Aliases for CXorf56 Gene
External Ids for CXorf56 Gene
- HGNC: 26239
- Entrez Gene: 63932
- Ensembl: ENSG00000018610
- UniProtKB: Q9H5V9
Previous GeneCards Identifiers for CXorf56 Gene
- GC0XM118556
- GC0XM118672
- GC0XM108165
Summaries for CXorf56 Gene
-
While this gene is well-supported by transcript data, no functional information on its protein products is currently available. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
GeneCards Summary for CXorf56 Gene
CXorf56 (Chromosome X Open Reading Frame 56) is a Protein Coding gene.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf56 Gene
Genomics for CXorf56 Gene
Regulatory Elements for CXorf56 Gene
Enhancers for CXorf56 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CXorf56 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CXorf56 gene promoter:
Regulatory Element Products
Genomic Location for CXorf56 Gene
- Chromosome:
- X
- Start:
- 119,538,149 bp from pter
- End:
- 119,565,434 bp from pter
- Size:
- 27,286 bases
- Orientation:
- Minus strand
Genomic View for CXorf56 Gene
Genes around CXorf56 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq24 by Ensembl
- Xq24 by Entrez Gene
- Xq24 by HGNC
CXorf56 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CXorf56 Gene
Proteins for CXorf56 Gene
-
Protein details for CXorf56 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H5V9-CX056_HUMAN
- Recommended name:
- UPF0428 protein CXorf56
- Protein Accession:
- Q9H5V9
- A8MPX7
- B4DQN2
- D3DWH9
- F5GWL7
- O43351
Protein attributes for CXorf56 Gene
- Size:
- 222 amino acids
- Molecular mass:
- 25625 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAB96348.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for CXorf56 Gene
Post-translational modifications for CXorf56 Gene
Other Protein References for CXorf56 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CXorf56
- Novus Biologicals Antibodies for CXorf56
-
Abcam antibodies for CXorf56
- Invitrogen Antibodies for CXorf56
- antibodies-online Antibodies for CXorf56: See all 15
- Search GeneTex for Antibodies for CXorf56
Protein Products
-
OriGene Purified Proteins for CXorf56
- Search Origene for MassSpec and Protein Over-expression Lysates for CXorf56
- Origene Custom Protein Services for CXorf56
- Search GeneTex for Proteins for CXorf56
Assay Products
No data available for DME Specific Peptides for CXorf56 Gene
Domains & Families for CXorf56 Gene
Protein Domains for CXorf56 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CXorf56 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H5V9- Family:
-
- Belongs to the UPF0428 family.
No data available for Gene Families for CXorf56 Gene
Function for CXorf56 Gene
Phenotypes for CXorf56 Gene
- MGI mutant phenotypes for CXorf56:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CXorf56:
Animal Model Products
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- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf56
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf56 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf56 gene
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CRISPR Products
-
OriGene CRISPR knockouts for CXorf56
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf56
- GenScript: Design CRISPR guide RNA sequences for CXorf56
miRNA for CXorf56 Gene
- miRTarBase miRNAs that target CXorf56
-
- hsa-mir-92a-3p (MIRT049078)
- hsa-mir-4772-3p (MIRT663878)
- hsa-mir-6787-3p (MIRT663879)
- hsa-mir-4740-3p (MIRT663880)
- hsa-mir-6736-3p (MIRT663881)
- hsa-mir-6890-3p (MIRT663882)
- hsa-mir-1306-5p (MIRT663883)
- hsa-mir-216a-5p (MIRT663884)
- hsa-mir-665 (MIRT685000)
- hsa-mir-6771-5p (MIRT685001)
- hsa-mir-7160-5p (MIRT685002)
- hsa-mir-4722-5p (MIRT685003)
- hsa-mir-6884-5p (MIRT685004)
- hsa-mir-485-5p (MIRT685005)
- hsa-mir-1827 (MIRT685006)
- hsa-mir-4649-3p (MIRT685007)
- hsa-mir-6746-5p (MIRT685008)
- hsa-mir-4768-3p (MIRT685009)
- hsa-mir-5690 (MIRT685010)
- hsa-mir-4478 (MIRT685011)
- hsa-mir-4419b (MIRT685012)
- hsa-mir-3929 (MIRT685013)
- hsa-mir-940 (MIRT685014)
- hsa-mir-6893-5p (MIRT685015)
- hsa-mir-6808-5p (MIRT685016)
- hsa-mir-6771-3p (MIRT685017)
- hsa-mir-1304-5p (MIRT694607)
- hsa-mir-548s (MIRT694608)
- hsa-mir-620 (MIRT694609)
- hsa-mir-1270 (MIRT694610)
- hsa-mir-4531 (MIRT694611)
- hsa-mir-664b-3p (MIRT694612)
- hsa-mir-579-3p (MIRT694613)
- hsa-mir-6880-5p (MIRT694614)
- hsa-mir-8071 (MIRT694615)
- hsa-mir-3926 (MIRT694616)
- hsa-mir-571 (MIRT694617)
- hsa-mir-3190-5p (MIRT694618)
- hsa-mir-6849-3p (MIRT694619)
miRNA Products
- Search ViGene Biosciences for CXorf56
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf56
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-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf56 gene
Clone Products
- Sino Biological Human cDNA Clone for CXorf56
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CXorf56 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf56 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf56 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf56 Gene
Localization for CXorf56 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| mitochondrion | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf56 Gene
Transcripts for CXorf56 Gene
mRNA/cDNA for CXorf56 Gene
- (3) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (117) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CXorf56 Gene
- Chromosome X open reading frame 56:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CXorf56
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf56
- GenScript: Design CRISPR guide RNA sequences for CXorf56
miRNA Products
- Search ViGene Biosciences for CXorf56
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf56
- Browse OriGene Inhibitory RNA Products For CXorf56
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf56 gene
Clone Products
- Sino Biological Human cDNA Clone for CXorf56
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXorf56
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf56
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CXorf56 Gene
This gene is overexpressed in Bone (33.7) and Peripheral blood mononuclear cells (9.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CXorf56 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CXorf56 Gene:
CXorf56SOURCE GeneReport for Unigene cluster for CXorf56 Gene:
Hs.248572Evidence on tissue expression from TISSUES for CXorf56 Gene
- Nervous system(2.7)
Primer Products
-
OriGene qPCR primer pairs and template standards for CXorf56
-
OriGene qPCR primer pairs for CXorf56
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf56 Gene
Orthologs for CXorf56 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
OneToMany | |
| CXHXorf56 34 |
|
||||
| -- 35 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | CXorf56 35 |
|
OneToOne | |
| CXHXorf56 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | CXorf56 35 |
|
OneToOne | |
| CXHXorf56 34 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | CXorf56 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CXorf56 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | C330007P06Rik 16 35 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | RGD1564541 34 |
|
||
| chicken (Gallus gallus) |
Aves | CXorf56 35 |
|
OneToOne | |
| CXORF56 34 |
|
||||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cxorf56 34 |
|
||
| MGC76077 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | c330007p06-A-prov 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | C5HXorf56 35 |
|
OneToOne | |
| zgc:103697 34 |
|
||||
| Dr.17887 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2208 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005769 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG16865 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | Y66D12A.8 34 35 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.6041 34 |
|
- Species where no ortholog for CXorf56 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CXorf56 Gene
Pseudogenes.org Pseudogenes for CXorf56 Gene
No data available for Paralogs for CXorf56 Gene
Variants for CXorf56 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000028074 | -- | 119,562,757(+) | TTTAA(A/T)ATAAT | intron-variant | |
| rs1000089773 | -- | 119,549,363(+) | ATACC(C/T)CAATA | intron-variant | |
| rs1000137636 | -- | 119,554,025(+) | TTCAA(C/G)TGGTA | intron-variant | |
| rs1000170705 | -- | 119,553,601(+) | GTCAA(A/T)GGTGC | intron-variant | |
| rs1000374092 | -- | 119,544,662(+) | TAGGC(C/T)GGGCG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3574414 | CNV | loss | 25503493 |
| nsv525652 | CNV | gain | 19592680 |
Residual Variation Intolerance Score:
42.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.11;
2.42% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CXorf56 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CXorf56
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf56 Gene
Disorders for CXorf56 Gene
Relevant External Links for CXorf56
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CXorf56
No disorders were found for CXorf56 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf56 Gene
Publications for CXorf56 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1. (PMID: 26752685) Scholz C.C. … Taylor C.T. (PLoS Biol. 2016) 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
Products for CXorf56 Gene
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- Browse Primary Antibodies
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- Custom Antibody ServicesOriGene Antibodies for CXorf56
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- Custom Assay Services
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- OriGene qPCR primer pairs and template standards for CXorf56
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- Novus Biologicals Antibodies for CXorf56
- Novus Biologicals proteins and lysates for CXorf56
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for CXorf56 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CXorf56 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CXorf56 gene
- Search ViGene Biosciences for CXorf56
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf56
- VectorBuilder custom plasmid, inducible vectors for CXorf56
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf56
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CXorf56 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer