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Aliases for CXorf49B Gene

Aliases for CXorf49B Gene

  • Chromosome X Open Reading Frame 49B 2 3 5
  • Uncharacterized Protein CXorf49 3
  • CXorf49 CXorf49B 4
  • CXorf49 3

External Ids for CXorf49B Gene

Previous GeneCards Identifiers for CXorf49B Gene

  • GC0XP070903
  • GC0XP070983

Summaries for CXorf49B Gene

GeneCards Summary for CXorf49B Gene

CXorf49B (Chromosome X Open Reading Frame 49B) is a Protein Coding gene. An important paralog of this gene is CXorf49.

Additional gene information for CXorf49B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf49B Gene

Genomics for CXorf49B Gene

Regulatory Elements for CXorf49B Gene

Enhancers for CXorf49B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH071782 0.2 Ensembl 0.3 +20.2 20220 2.6 LOC100132741 CXorf49B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CXorf49B on UCSC Golden Path with GeneCards custom track

Genomic Locations for CXorf49B Gene

Genomic Locations for CXorf49B Gene
3,915 bases
Plus strand

Genomic View for CXorf49B Gene

Genes around CXorf49B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf49B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf49B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf49B Gene

Proteins for CXorf49B Gene

  • Protein details for CXorf49B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein CXorf49
    Protein Accession:

    Protein attributes for CXorf49B Gene

    514 amino acids
    Molecular mass:
    54417 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CXorf49B Gene

Post-translational modifications for CXorf49B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CXorf49B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CXorf49B Gene

Domains & Families for CXorf49B Gene

Gene Families for CXorf49B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CXorf49B Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf49B: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CXorf49B Gene

Function for CXorf49B Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CXorf49B Gene

Localization for CXorf49B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CXorf49B Gene

Pathways & Interactions for CXorf49B Gene

SuperPathways for CXorf49B Gene

No Data Available

Interacting Proteins for CXorf49B Gene

Gene Ontology (GO) - Biological Process for CXorf49B Gene


No data available for Pathways by source and SIGNOR curated interactions for CXorf49B Gene

Drugs & Compounds for CXorf49B Gene

No Compound Related Data Available

Transcripts for CXorf49B Gene

mRNA/cDNA for CXorf49B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXorf49B Gene

Chromosome X open reading frame 49B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf49B Gene

No ASD Table

Relevant External Links for CXorf49B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CXorf49B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CXorf49B Gene

Protein differential expression in normal tissues from HIPED for CXorf49B Gene

This gene is overexpressed in Testis (44.1), Adipocyte (17.4), and Ovary (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CXorf49B Gene

Protein tissue co-expression partners for CXorf49B Gene

NURSA nuclear receptor signaling pathways regulating expression of CXorf49B Gene:


SOURCE GeneReport for Unigene cluster for CXorf49B Gene:

genes like me logo Genes that share expression patterns with CXorf49B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf49B Gene

Orthologs for CXorf49B Gene

This gene was present in the common ancestor of mammals.

Orthologs for CXorf49B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC737558 33
  • 99.03 (n)
(Canis familiaris)
Mammalia LOC608319 33
  • 71.91 (n)
(Bos Taurus)
Mammalia MGC152340 33
  • 63.43 (n)
(Rattus norvegicus)
Mammalia LOC100361265 33
  • 59.2 (n)
(Mus musculus)
Mammalia LOC102634296 33
  • 55.21 (n)
Gm4779 16
Species where no ortholog for CXorf49B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CXorf49B Gene

Gene Tree for CXorf49B (if available)
Gene Tree for CXorf49B (if available)

Paralogs for CXorf49B Gene

Paralogs for CXorf49B Gene

genes like me logo Genes that share paralogs with CXorf49B: view

Variants for CXorf49B Gene

Sequence variations from dbSNP and Humsavar for CXorf49B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs2334300 -- 71,764,421(+) GGCCC(C/T)GGGGA reference, missense
rs368446983 -- 71,762,410(+) CAAAC(A/G)GCTAC upstream-variant-2KB
rs56409424 -- 71,762,194(+) GGCCG(A/G)CCTTC upstream-variant-2KB
rs62608629 -- 71,766,623(-) AAGTC(A/G)TACCA intron-variant
rs77458208 -- 71,762,176(+) TCGTC(A/G)ACTGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CXorf49B Gene

Variant ID Type Subtype PubMed ID
nsv9954 CNV loss 18304495
nsv9952 CNV loss 18304495
nsv7449 OTHER inversion 18451855
nsv1147790 CNV duplication 26484159
esv3576925 CNV gain 25503493
esv33082 CNV loss 17666407
esv2758872 CNV loss 17122850
esv2740215 CNV deletion 23290073
esv1584074 OTHER inversion 17803354
dgv516n21 CNV loss 19592680

Relevant External Links for CXorf49B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CXorf49B Gene

Disorders for CXorf49B Gene

Relevant External Links for CXorf49B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CXorf49B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf49B Gene

Publications for CXorf49B Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for CXorf49B Gene

Sources for CXorf49B Gene

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