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Aliases for CXorf40B Gene

Aliases for CXorf40B Gene

  • Chromosome X Open Reading Frame 40B 2 3 5

External Ids for CXorf40B Gene

Previous GeneCards Identifiers for CXorf40B Gene

  • GC0XU900620
  • GC0XM148851
  • GC0XM149097
  • GC0XM137971

Summaries for CXorf40B Gene

GeneCards Summary for CXorf40B Gene

CXorf40B (Chromosome X Open Reading Frame 40B) is a Protein Coding gene. An important paralog of this gene is CXorf40A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf40B Gene

Genomics for CXorf40B Gene

Regulatory Elements for CXorf40B Gene

Enhancers for CXorf40B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around CXorf40B on UCSC Golden Path with GeneCards custom track

Promoters for CXorf40B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for CXorf40B Gene

Chromosome:
X
Start:
149,924,157 bp from pter
End:
149,938,850 bp from pter
Size:
14,694 bases
Orientation:
Minus strand

Genomic View for CXorf40B Gene

Genes around CXorf40B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf40B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf40B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf40B Gene

Proteins for CXorf40B Gene

  • Protein details for CXorf40B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96DE9-CX04B_HUMAN
    Recommended name:
    Protein CXorf40B
    Protein Accession:
    Q96DE9

    Protein attributes for CXorf40B Gene

    Size:
    158 amino acids
    Molecular mass:
    17780 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CXorf40B Gene

Post-translational modifications for CXorf40B Gene

No Post-translational modifications

Other Protein References for CXorf40B Gene

No data available for DME Specific Peptides for CXorf40B Gene

Domains & Families for CXorf40B Gene

Protein Domains for CXorf40B Gene

Suggested Antigen Peptide Sequences for CXorf40B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf40B: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CXorf40B Gene

Function for CXorf40B Gene

Phenotypes for CXorf40B Gene

GenomeRNAi human phenotypes for CXorf40B:
genes like me logo Genes that share phenotypes with CXorf40B: view

Animal Model Products

CRISPR Products

miRNA for CXorf40B Gene

miRTarBase miRNAs that target CXorf40B

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf40B Gene

Localization for CXorf40B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CXorf40B Gene

Pathways & Interactions for CXorf40B Gene

SuperPathways for CXorf40B Gene

No Data Available

Interacting Proteins for CXorf40B Gene

Selected Interacting proteins: Q96DE9-CX04B_HUMAN for CXorf40B Gene via IID

Symbol External ID(s) Details
CXorf40A

Gene Ontology (GO) - Biological Process for CXorf40B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CXorf40B Gene

Drugs & Compounds for CXorf40B Gene

No Compound Related Data Available

Transcripts for CXorf40B Gene

mRNA/cDNA for CXorf40B Gene

(18) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXorf40B Gene

Chromosome X open reading frame 40B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf40B Gene

No ASD Table

Relevant External Links for CXorf40B Gene

GeneLoc Exon Structure for
CXorf40B
ECgene alternative splicing isoforms for
CXorf40B

Expression for CXorf40B Gene

mRNA expression in normal human tissues for CXorf40B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CXorf40B Gene



NURSA nuclear receptor signaling pathways regulating expression of CXorf40B Gene:

CXorf40B

SOURCE GeneReport for Unigene cluster for CXorf40B Gene:

Hs.545950
genes like me logo Genes that share expression patterns with CXorf40B: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CXorf40B Gene

Orthologs for CXorf40B Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf40B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia CXHXorf40A 34
  • 79.96 (n)
  • 77.85 (a)
-- 35
  • 78 (a)
ManyToMany
-- 35
  • 78 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia 1110012L19Rik 34
  • 80.04 (n)
  • 75.8 (a)
1110012L19Rik 16
1110012L19Rik 35
  • 76 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia CXHXorf40A 34
  • 98.1 (n)
  • 96.2 (a)
-- 35
  • 96 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1562747 34
  • 80.89 (n)
  • 78.98 (a)
cow
(Bos Taurus)
Mammalia -- 35
  • 60 (a)
ManyToMany
-- 35
  • 63 (a)
ManyToMany
-- 35
  • 75 (a)
ManyToMany
-- 35
  • 52 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 67 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 73 (a)
OneToMany
chicken
(Gallus gallus)
Aves LOC772269 34
  • 66.01 (n)
  • 66.01 (a)
-- 35
  • 63 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 63 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia cxorf40a 34
  • 64.49 (n)
  • 63.4 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:110222 34
  • 56.33 (n)
  • 56.96 (a)
C21HXorf40A 35
  • 52 (a)
OneToMany
Species where no ortholog for CXorf40B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf40B Gene

ENSEMBL:
Gene Tree for CXorf40B (if available)
TreeFam:
Gene Tree for CXorf40B (if available)

Paralogs for CXorf40B Gene

Paralogs for CXorf40B Gene

(1) SIMAP similar genes for CXorf40B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with CXorf40B: view

Variants for CXorf40B Gene

Sequence variations from dbSNP and Humsavar for CXorf40B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs542089 -- 149,933,716(+) TCCCG(A/C)CAGGC reference, missense
rs544768 -- 149,934,016(+) GGTCT(C/G)CTGCT utr-variant-5-prime
rs544843 -- 149,934,041(+) ATGTC(C/G)AGCAC utr-variant-5-prime
rs567601 -- 149,934,162(+) GGATA(C/G)CATGT intron-variant
rs626113 -- 149,933,788(-) CGTCC(C/T)CTGCT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for CXorf40B Gene

Variant ID Type Subtype PubMed ID
esv3577519 CNV gain 25503493
nsv525908 CNV gain 19592680
nsv7464 OTHER inversion 18451855
nsv9996 CNV gain 18304495

Variation tolerance for CXorf40B Gene

Residual Variation Intolerance Score: 87.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.71; 15.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CXorf40B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CXorf40B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf40B Gene

Disorders for CXorf40B Gene

Relevant External Links for CXorf40B

Genetic Association Database (GAD)
CXorf40B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CXorf40B

No disorders were found for CXorf40B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf40B Gene

Publications for CXorf40B Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. 130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus. (PMID: 8717057) Timms K.M. … Gibbs R.A. (Genome Res. 1995) 3 4 65
  4. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 46 65
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3 65

Products for CXorf40B Gene

Sources for CXorf40B Gene

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