CXorf40B Gene
protein-coding GIFtS: 37
GCID: GC0XM149097
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chromosome X open reading frame 40B
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Aliases
for CXorf40B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome X Open Reading Frame 40B1 2 | | Protein CXorf40B2 |
Export aliases for CXorf40B gene to outside databasesPrevious GC identifers: GC0XU900620 GC0XM148851 GC0XM137971 |
Summaries
for CXorf40B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CXorf40B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167198.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CXorf40B gene promoter:
SREBP-1c NCX/Ncx Lmo2 CUTL1 SREBP-1b E47 SREBP-1a FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CXorf40B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXorf40B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28CXorf40B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM149097: view genomic region
(about GC identifiers)
Start:
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149,097,745 bp from pter |
End:
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149,107,029 bp from pter |
Size:
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9,285 bases |
Orientation:
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minus strand |
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Proteins
for CXorf40B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CX04B_HUMAN, Q96DE9 (See
protein sequence)Recommended Name: Protein CXorf40B Size: 158 amino acids; 17780 DaExplore the universe of human proteins at neXtProt for CXorf40B: NX_Q96DE9
CXorf40B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001013867.1
ENSEMBL proteins: ENSP00000417546 ENSP00000359434 ENSP00000347339 ENSP00000359432
Human Recombinant Protein Products:
CXorf40B Antibody Products:
Assay Products for CXorf40B: |
Protein
Domains /
Families
for CXorf40B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CXorf40B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96DE9ProtoNet protein and cluster: Q96DE9 |
Function
for CXorf40B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CXorf40B (NM_001013845) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CXorf40B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf40B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXorf40B |
|
Pathways & Interactions
for CXorf40B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CXorf40B
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for CXorf40B (ENSP000003473394) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for CXorf40B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CXorf40B
Search CenterWatch for drugs/clinical trials and news about CXorf40B / CX04B
|
Transcripts
for CXorf40B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CXorf40B gene: NM_001013845.1 Unigene Cluster for CXorf40B: Chromosome X open reading frame 40B Hs.545950 [show with all ESTs]Unigene Representative Sequence: NM_0010138457 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000462691(uc011mxs.1) ENST00000370406(uc004fdy.3) ENST00000355203
ENST00000370404 ENST00000370409 ENST00000483447 ENST00000497550(uc004fdz.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CXorf40B (NM_001013845) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CXorf40B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf40B |
Additional cDNA sequence: BC009523.1 L43575.1 L43578.1 U66042.1 U66051.1 17 DOTS entries: DT.95366192 DT.95366214 DT.100815520 DT.121321350 DT.121321306 DT.92450174 DT.121321333 DT.95366205 DT.95366208 DT.121299174 DT.95098591 DT.100768177 DT.100815530 DT.101977157 DT.121321380 DT.92450175 DT.95366195
GeneLoc Exon Structure
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Expression
for CXorf40B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CXorf40B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAACAGGTT
About this image
See CXorf40B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CXorf40B
SOURCE GeneReport for Unigene cluster: Hs.545950
SABiosciences Custom PCR Arrays for CXorf40B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXorf40B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CXorf40B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CXorf40B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CXorf40B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXorf40B |
Orthologs
for CXorf40B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CXorf40B gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for CXorf40B (if available)
TreeFam Gene Tree for CXorf40B (if available) |
Paralogs
for CXorf40B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CXorf40B gene
- CXorf40A1 2
1 SIMAP similar gene for CXorf40B using alignment to 2 protein entries: CX04B_HUMAN (see all proteins):CXorf40A
CXorf40B for paralogs About GeneDecksing
|
Genomic Variants
for CXorf40B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for CXorf40B (149097745 - 149107029 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for CXorf40B
6 CNVs: 3258 97069 31572 83835 83833 97068
1 Indel: 97071 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXorf40B |
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Disorders
/ Diseases
for CXorf40B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CXorf40B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CXorf40B gene integrated from 9 sources:
(articles sorted by number of sources associating them with CXorf40B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- 130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus. (PubMed id 8717057)1, 2 Timms K.M.... Gibbs R.A. (1995)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Molecular and phenotypic variation in patients with severe Hunter syndrome. (PubMed id 9147653)1 Timms K.M.... Gibbs R.A. (1997)
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External Searches for CXorf40B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CXorf40B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CXorf40B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CXorf40B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CXorf40B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CXorf40B gene:
Search GeneIP for patents involving CXorf40B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CXorf40B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CXorf40B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CXorf40B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXorf40B | | | OriGene Protein Over-expression Lysate for CXorf40B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CXorf40B | | OriGene 3'-UTR Clone for CXorf40B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXorf40B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CXorf40B | | OriGene Custom Protein Services for CXorf40B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CXorf40B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXorf40B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXorf40B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CXorf40B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CXorf40B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CXorf40B |
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 | | | CXorf40B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXorf40B |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXorf40B |
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