Aliases for CXorf40A Gene
Aliases for CXorf40A Gene
External Ids for CXorf40A Gene
- HGNC: 28089
- Entrez Gene: 91966
- Ensembl: ENSG00000197620
- OMIM: 300954
- UniProtKB: Q8TE69
Previous HGNC Symbols for CXorf40A Gene
- CXorf40
Previous GeneCards Identifiers for CXorf40A Gene
- GC0XP148328
- GC0XP148432
- GC0XP148623
- GC0XP137575
Summaries for CXorf40A Gene
GeneCards Summary for CXorf40A Gene
CXorf40A (Chromosome X Open Reading Frame 40A) is a Protein Coding gene. An important paralog of this gene is CXorf40B.
UniProtKB/Swiss-Prot for CXorf40A Gene
-
May have an important role of cell protection in inflammation reaction.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf40A Gene
Genomics for CXorf40A Gene
Regulatory Elements for CXorf40A Gene
Enhancers for CXorf40A Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH0XG149510 | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 25.1 | -27.4 | -27381 | 5.1 | CTCF PKNOX1 JUN CEBPG RAD21 CTBP1 GATA3 ZNF143 SMC3 FOSL2 | IDS2 CXorf40A ENSG00000241489 LINC00893 IDS GC0XP149503 |
| GH0XG149502 | 1.3 | ENCODE dbSUPER | 28 | -35.8 | -35829 | 4.2 | HDGF PKNOX1 SIN3A YBX1 ZBTB7B FOS SP3 REST KAT8 ZNF610 | CXorf40A LINC00893 ENSG00000241489 TMEM185AP1 CXorf40B LINC00894 IDS2 GC0XP149503 IDS |
| GH0XG149538 | 1.3 | ENCODE dbSUPER | 14.5 | +0.2 | 181 | 3.1 | HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZBTB7B YY1 ZNF143 FOS ZNF263 | TMEM185A CXorf40A CXorf40B IDS2 LINC00893 |
| GH0XG149516 | 0.7 | ENCODE | 24.7 | -23.7 | -23707 | 0.6 | RNF2 NR2F1 TAL1 MAFG DPF2 TCF12 ARID1B ZNF316 NCOR1 IKZF1 | IDS2 CXorf40A LINC00893 IDS GC0XP149503 |
| GH0XG149520 | 0.9 | ENCODE dbSUPER | 11.9 | -18.2 | -18248 | 3.2 | ATF2 YY1 JUND ATF3 MTA1 HNF4G HNF4A CREM | IDS2 CXorf40A IDSP1 IDS |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CXorf40A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CXorf40A Gene
- Chromosome:
- X
- Start:
- 149,540,355 bp from pter
- End:
- 149,555,340 bp from pter
- Size:
- 14,986 bases
- Orientation:
- Plus strand
Genomic View for CXorf40A Gene
Genes around CXorf40A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq28 by Ensembl
- Xq28 by Entrez Gene
- Xq28 by HGNC
CXorf40A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CXorf40A Gene
Proteins for CXorf40A Gene
-
Protein details for CXorf40A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TE69-CX04A_HUMAN
- Recommended name:
- Protein CXorf40A
- Protein Accession:
- Q8TE69
- A8K784
- B7Z6H6
- B7ZL96
- D6RA72
- E7ENU3
- Q2M3E9
Protein attributes for CXorf40A Gene
- Size:
- 158 amino acids
- Molecular mass:
- 17921 Da
- Quaternary structure:
-
- Interacts with MT2A.
Protein Expression for CXorf40A Gene
Post-translational modifications for CXorf40A Gene
No Post-translational modifications
Other Protein References for CXorf40A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CXorf40A
- Novus Biologicals Antibodies for CXorf40A
-
Abcam antibodies for CXorf40A
- Invitrogen Antibodies for CXorf40A
- antibodies-online Antibodies for CXorf40A: See all 3
- Search GeneTex for Antibodies for CXorf40A
Protein Products
-
OriGene Purified Proteins for CXorf40A
- Search Origene for MassSpec and Protein Over-expression Lysates for CXorf40A
- Origene Custom Protein Services for CXorf40A
- Novus Biologicals lysates for CXorf40A
- Search GeneTex for Proteins for CXorf40A
Assay Products
No data available for DME Specific Peptides for CXorf40A Gene
Domains & Families for CXorf40A Gene
Protein Domains for CXorf40A Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CXorf40A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CXorf40A Gene
Function for CXorf40A Gene
Molecular function for CXorf40A Gene
- UniProtKB/Swiss-Prot Function:
- May have an important role of cell protection in inflammation reaction.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15541360 |
Phenotypes for CXorf40A Gene
- GenomeRNAi human phenotypes for CXorf40A:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf40A
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf40A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf40A gene
- Search ViGene Biosciences for CXorf40A
CRISPR Products
-
OriGene CRISPR knockouts for CXorf40A
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf40A
- GenScript: Design CRISPR guide RNA sequences for CXorf40A
miRNA Products
- Search ViGene Biosciences for CXorf40A
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf40A
- Browse OriGene Inhibitory RNA Products For CXorf40A
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf40A gene
Clone Products
-
OriGene ORF clones in human for CXorf40A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CXorf40A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXorf40A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf40A
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CXorf40A
-
ViGene Biosciences adenoviral particle packaged cDNA for CXorf40A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CXorf40A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf40A gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CXorf40A Gene
Localization for CXorf40A Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CXorf40A Gene
Pathways & Interactions for CXorf40A Gene
No Data Available
Interacting Proteins for CXorf40A Gene
Selected Interacting proteins:
ENSP00000420882
Q8TE69-CX04A_HUMAN
for CXorf40A Gene via
STRING
UniProtKB
IID
No data available for Pathways by source and SIGNOR curated interactions for CXorf40A Gene
Transcripts for CXorf40A Gene
mRNA/cDNA for CXorf40A Gene
- (12) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (162) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CXorf40A Gene
CRISPR Products
-
OriGene CRISPR knockouts for CXorf40A
-
Santa Cruz Biotechnology (SCBT) CRISPR for CXorf40A
- GenScript: Design CRISPR guide RNA sequences for CXorf40A
miRNA Products
- Search ViGene Biosciences for CXorf40A
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CXorf40A
- Browse OriGene Inhibitory RNA Products For CXorf40A
-
ViGene Biosciences ready-to-package AAV shRNAs for CXorf40A gene
Clone Products
-
OriGene ORF clones in human for CXorf40A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CXorf40A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CXorf40A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf40A
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CXorf40A Gene
This gene is overexpressed in Adipocyte (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CXorf40A Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CXorf40A Gene:
CXorf40ASOURCE GeneReport for Unigene cluster for CXorf40A Gene:
Hs.534641mRNA Expression by UniProt/SwissProt for CXorf40A Gene:
Q8TE69-CX04A_HUMAN
Tissue specificity:
Expressed primarily in heart, skeletal muscle, kidney, liver and placenta. Relatively high level of expression in spleen, colon and small intestine. Almost no expression in brain, thymus, lung and peripheral blood leukocytes.
Evidence on tissue expression from TISSUES for CXorf40A Gene
- Nervous system(3.9)
- Lung(3.3)
Primer Products
-
OriGene qPCR primer pairs for CXorf40A
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CXorf40A Gene
Orthologs for CXorf40A Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CXHXorf40A 34 |
|
||
| -- 35 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | RGD1562747 34 |
|
||
| mouse (Mus musculus) |
Mammalia | 1110012L19Rik 35 34 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | CXHXorf40A 34 |
|
||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | LOC772269 34 |
|
||
| -- 35 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cxorf40a 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16160 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zgc:110222 34 |
|
||
| C21HXorf40A 35 |
|
OneToMany | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1060 34 |
|
- Species where no ortholog for CXorf40A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CXorf40A Gene
(1) SIMAP similar genes for CXorf40A Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for CXorf40A Gene
Variants for CXorf40A Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10482432 | -- | 149,554,995(+) | acctt(C/T)ttaca | utr-variant-3-prime | |
| rs11117532 | -- | 149,545,209(+) | CAGAG(C/G)GTGGG | intron-variant | |
| rs111314546 | -- | 149,540,963(+) | TTGCG(A/C)GCCCA | intron-variant, upstream-variant-2KB | |
| rs111737620 | -- | 149,555,400(+) | TCTAA(C/G)TTCAC | downstream-variant-500B | |
| rs111817192 | -- | 149,539,255(+) | GGGGG(A/T)AGACA | intron-variant, upstream-variant-2KB |
Residual Variation Intolerance Score:
77.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.15;
3.39% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CXorf40A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CXorf40A
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf40A Gene
Disorders for CXorf40A Gene
Relevant External Links for CXorf40A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CXorf40A
No disorders were found for CXorf40A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf40A Gene
Publications for CXorf40A Gene
- [Purification of human endothelial overexpressed lipopolysaccharide-associated factor 1 protein]. (PMID: 16383041) Cai Z. … Su Y.Y. (Zhonghua Shao Shang Za Zhi 2005) 2 3 22 64
- Identification and characterization of a novel gene EOLA1 stimulating ECV304 cell proliferation. (PMID: 15541360) Liang Z. … Yang Z. (Biochem. Biophys. Res. Commun. 2004) 3 4 22 64
- 130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus. (PMID: 8717057) Timms K.M. … Gibbs R.A. (Genome Res. 1995) 2 3 4 64
- [The effect of inhibiting EOLA1 expression in ECV304 cells]. (PMID: 17557240) Liang Z.W. … Wang X.M. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007) 3 22 64
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
Products for CXorf40A Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
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- Custom Antibody ServicesOriGene Antibodies for CXorf40A
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- OriGene Purified Proteins for CXorf40A
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- Origene Custom Protein Services for CXorf40A
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- OriGene qPCR primer pairs for CXorf40A
- OriGene CRISPR knockouts for CXorf40A
- OriGene ORF clones in human for CXorf40A
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- Browse OriGene miRNA Products For CXorf40A
- GenScript: Next-day shipping cDNA ORF clone for CXorf40A in any vector
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- GenScript: Design CRISPR guide RNA sequences for CXorf40A
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- CloneReady with Over 120,000 Genes
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- Novus Biologicals Antibodies for CXorf40A
- Novus Biologicals lysates for CXorf40A
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for CXorf40A gene
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- ViGene Biosciences ready-to-package AAV shRNAs for CXorf40A gene
- Search ViGene Biosciences for CXorf40A
- Horizon Cell Lines for CXorf40A
- Cyagen custom Knockout/knockin (KOKI) mouse models for CXorf40A
- VectorBuilder custom plasmid, inducible vectors for CXorf40A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CXorf40A
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CXorf40A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer