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Aliases for CXorf38 Gene

Aliases for CXorf38 Gene

  • Chromosome X Open Reading Frame 38 2 3 5

External Ids for CXorf38 Gene

Previous GeneCards Identifiers for CXorf38 Gene

  • GC0XM040244
  • GC0XM040373
  • GC0XM040488
  • GC0XM038197

Summaries for CXorf38 Gene

GeneCards Summary for CXorf38 Gene

CXorf38 (Chromosome X Open Reading Frame 38) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf38 Gene

Genomics for CXorf38 Gene

Regulatory Elements for CXorf38 Gene

Enhancers for CXorf38 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CXorf38 on UCSC Golden Path with GeneCards custom track

Promoters for CXorf38 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CXorf38 on UCSC Golden Path with GeneCards custom track

Genomic Location for CXorf38 Gene

Chromosome:
X
Start:
40,626,921 bp from pter
End:
40,647,567 bp from pter
Size:
20,647 bases
Orientation:
Minus strand

Genomic View for CXorf38 Gene

Genes around CXorf38 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf38 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf38 Gene

Proteins for CXorf38 Gene

  • Protein details for CXorf38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TB03-CX038_HUMAN
    Recommended name:
    Uncharacterized protein CXorf38
    Protein Accession:
    Q8TB03
    Secondary Accessions:
    • B3KW28
    • D3DWB5
    • Q5JPF5
    • Q8N941

    Protein attributes for CXorf38 Gene

    Size:
    319 amino acids
    Molecular mass:
    36670 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CXorf38 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CXorf38 Gene

Proteomics data for CXorf38 Gene at MOPED

Post-translational modifications for CXorf38 Gene

  • Ubiquitination at Lys 20 and Lys 276
  • Modification sites at PhosphoSitePlus

Other Protein References for CXorf38 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CXorf38 Gene

Domains & Families for CXorf38 Gene

Protein Domains for CXorf38 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf38: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CXorf38 Gene

Function for CXorf38 Gene

genes like me logo Genes that share phenotypes with CXorf38: view

Animal Model Products

CRISPR Products

miRNA for CXorf38 Gene

miRTarBase miRNAs that target CXorf38

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf38 Gene

Localization for CXorf38 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CXorf38 Gene COMPARTMENTS Subcellular localization image for CXorf38 gene
Compartment Confidence
cytosol 3
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CXorf38 Gene

Pathways & Interactions for CXorf38 Gene

SuperPathways for CXorf38 Gene

No Data Available

Interacting Proteins for CXorf38 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000330488%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000330488 for CXorf38 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CXorf38 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CXorf38 Gene

Drugs & Compounds for CXorf38 Gene

No Compound Related Data Available

Transcripts for CXorf38 Gene

Unigene Clusters for CXorf38 Gene

Chromosome X open reading frame 38:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf38 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
SP1: -
SP2:
SP3: - -
SP4:

Relevant External Links for CXorf38 Gene

GeneLoc Exon Structure for
CXorf38
ECgene alternative splicing isoforms for
CXorf38

Expression for CXorf38 Gene

mRNA expression in normal human tissues for CXorf38 Gene

mRNA differential expression in normal tissues according to GTEx for CXorf38 Gene

This gene is overexpressed in Whole Blood (x4.5).

Protein differential expression in normal tissues from HIPED for CXorf38 Gene

This gene is overexpressed in Serum (36.9) and Bone (16.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CXorf38 Gene



SOURCE GeneReport for Unigene cluster for CXorf38 Gene Hs.495961

genes like me logo Genes that share expression patterns with CXorf38: view

Protein tissue co-expression partners for CXorf38 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CXorf38 Gene

Orthologs for CXorf38 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf38 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC616298 35
  • 89 (n)
  • 88.67 (a)
CXorf38 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CXHXorf38 35
  • 89.13 (n)
  • 88.09 (a)
CXorf38 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1810030O07Rik 35
  • 85.89 (n)
  • 86.52 (a)
1810030O07Rik 16
1810030O07Rik 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565685 35
  • 85.06 (n)
  • 84.95 (a)
oppossum
(Monodelphis domestica)
Mammalia CXorf38 36
  • 69 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CXorf38 36
  • 99 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CXorf38 36
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cxorf38 35
  • 58.51 (n)
  • 50.69 (a)
Str.9859 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.33719 35
zebrafish
(Danio rerio)
Actinopterygii C25HXorf38 (1 of 2) 36
  • 2 (a)
OneToMany
C25HXorf38 (2 of 2) 36
  • 1 (a)
OneToMany
Species with no ortholog for CXorf38:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf38 Gene

ENSEMBL:
Gene Tree for CXorf38 (if available)
TreeFam:
Gene Tree for CXorf38 (if available)

Paralogs for CXorf38 Gene

No data available for Paralogs for CXorf38 Gene

Variants for CXorf38 Gene

Sequence variations from dbSNP and Humsavar for CXorf38 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs17145855 - 40,637,102(+) CCACG(C/T)AGAAG reference, missense
rs747733567 -- 40,646,970(+) GACCC(A/G)CCGCT intron-variant
rs747738201 -- 40,629,779(+) GCTAA(-/T)TATTT intron-variant, downstream-variant-500B, utr-variant-3-prime
rs747775418 -- 40,637,489(+) TGTAA(C/T)GGTAA intron-variant
rs747826267 -- 40,627,724(+) TGATG(C/T)TACAT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CXorf38 Gene

Variant ID Type Subtype PubMed ID
esv33829 CNV Loss 17666407
nsv518965 CNV Gain 19592680
esv2550325 CNV Deletion 19546169
esv2740109 CNV Deletion 23290073
esv5571 CNV Loss 19470904

Variation tolerance for CXorf38 Gene

Residual Variation Intolerance Score: 55.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.81; 17.09% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CXorf38 Gene

Disorders for CXorf38 Gene

Relevant External Links for CXorf38

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CXorf38

No disorders were found for CXorf38 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf38 Gene

Publications for CXorf38 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for CXorf38 Gene

Sources for CXorf38 Gene

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