Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CXorf36 Gene

Aliases for CXorf36 Gene

  • Chromosome X Open Reading Frame 36 2 3 5
  • DIA1R 3 4
  • Deleted In Autism-1 Related Protein 3
  • UPF0672 Protein CXorf36 3
  • 4930578C19Rik 3
  • HCG1981635 3
  • BA435K1.1 3
  • EPQL1862 3
  • PRO3743 3

External Ids for CXorf36 Gene

Previous GeneCards Identifiers for CXorf36 Gene

  • GC0XM044765
  • GC0XM044892
  • GC0XM045007
  • GC0XM042724

Summaries for CXorf36 Gene

GeneCards Summary for CXorf36 Gene

CXorf36 (Chromosome X Open Reading Frame 36) is a Protein Coding gene. An important paralog of this gene is C3orf58.

Gene Wiki entry for CXorf36 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf36 Gene

Genomics for CXorf36 Gene

Regulatory Elements for CXorf36 Gene

Promoters for CXorf36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CXorf36 on UCSC Golden Path with GeneCards custom track

Genomic Location for CXorf36 Gene

45,148,373 bp from pter
45,200,901 bp from pter
52,529 bases
Minus strand

Genomic View for CXorf36 Gene

Genes around CXorf36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CXorf36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CXorf36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf36 Gene

Proteins for CXorf36 Gene

  • Protein details for CXorf36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Deleted in autism-related protein 1
    Protein Accession:
    Secondary Accessions:
    • A8MUU5
    • B2RPN7
    • Q6UWJ5

    Protein attributes for CXorf36 Gene

    433 amino acids
    Molecular mass:
    48555 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CXorf36 Gene


neXtProt entry for CXorf36 Gene

Proteomics data for CXorf36 Gene at MOPED

Post-translational modifications for CXorf36 Gene

Other Protein References for CXorf36 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CXorf36 Gene

Domains & Families for CXorf36 Gene

Protein Domains for CXorf36 Gene


Suggested Antigen Peptide Sequences for CXorf36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the DIA1 family.
  • Belongs to the DIA1 family.
genes like me logo Genes that share domains with CXorf36: view

No data available for Gene Families for CXorf36 Gene

Function for CXorf36 Gene

genes like me logo Genes that share phenotypes with CXorf36: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf36 Gene

Localization for CXorf36 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CXorf36 Gene


Subcellular locations from

Jensen Localization Image for CXorf36 Gene COMPARTMENTS Subcellular localization image for CXorf36 gene
Compartment Confidence
extracellular 4
cytoskeleton 1
cytosol 1
golgi apparatus 1
lysosome 1
peroxisome 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for CXorf36 Gene

Pathways & Interactions for CXorf36 Gene

SuperPathways for CXorf36 Gene

No Data Available

Interacting Proteins for CXorf36 Gene

Gene Ontology (GO) - Biological Process for CXorf36 Gene


No data available for Pathways by source and SIGNOR curated interactions for CXorf36 Gene

Drugs & Compounds for CXorf36 Gene

No Compound Related Data Available

Transcripts for CXorf36 Gene

Unigene Clusters for CXorf36 Gene

Chromosome X open reading frame 36:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf36 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b
SP1: - -
SP2: - - -
SP3: -
SP5: - - - - -
SP6: - - - - - - - -

Relevant External Links for CXorf36 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CXorf36 Gene

mRNA expression in normal human tissues for CXorf36 Gene

Protein differential expression in normal tissues from HIPED for CXorf36 Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CXorf36 Gene

SOURCE GeneReport for Unigene cluster for CXorf36 Gene Hs.98321

genes like me logo Genes that share expression patterns with CXorf36: view

Protein tissue co-expression partners for CXorf36 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CXorf36 Gene

Orthologs for CXorf36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf36 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CXHXorf36 35
  • 85.14 (n)
  • 83.14 (a)
CXHXorf36 36
  • 83 (a)
(Canis familiaris)
Mammalia CXHXorf36 35
  • 86.37 (n)
  • 82.45 (a)
CXorf36 36
  • 82 (a)
(Mus musculus)
Mammalia 4930578C19Rik 35
  • 83.76 (n)
  • 81.29 (a)
4930578C19Rik 16
4930578C19Rik 36
  • 81 (a)
(Pan troglodytes)
Mammalia CXHXorf36 35
  • 99.46 (n)
  • 99.08 (a)
CXorf36 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1559731 35
  • 81.79 (n)
  • 80.33 (a)
(Monodelphis domestica)
Mammalia CXorf36 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia CXorf36 36
  • 68 (a)
(Gallus gallus)
Aves C1HXORF36 35
  • 67.87 (n)
  • 67.07 (a)
CXorf36 36
  • 64 (a)
(Anolis carolinensis)
Reptilia CXorf36 36
  • 67 (a)
(Danio rerio)
Actinopterygii si:ch73-147f11.1 35
  • 55.85 (n)
  • 49.48 (a)
C9HXorf36 36
  • 42 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
Species with no ortholog for CXorf36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf36 Gene

Gene Tree for CXorf36 (if available)
Gene Tree for CXorf36 (if available)

Paralogs for CXorf36 Gene

Paralogs for CXorf36 Gene

(1) SIMAP similar genes for CXorf36 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CXorf36: view

Variants for CXorf36 Gene

Sequence variations from dbSNP and Humsavar for CXorf36 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1132201 - 45,191,866(-) CAGGA(A/G)AATCT reference, missense
rs9969 - 45,191,812(+) TTTTC(C/T)GCAGG reference, missense
rs11451 -- 45,148,491(+) GAAGG(C/T)GAAGG utr-variant-3-prime
rs4268237 -- 45,197,001(+) GGAGA(A/G)GTGAT intron-variant
rs4498684 -- 45,200,167(+) TCCCC(A/C)CACTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXorf36 Gene

Variant ID Type Subtype PubMed ID
nsv508765 CNV Insertion 20534489
nsv524833 CNV Gain 19592680

Variation tolerance for CXorf36 Gene

Residual Variation Intolerance Score: 94.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.81; 91.70% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CXorf36 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf36 Gene

Disorders for CXorf36 Gene


  • Note=Genetic variations in CXorf36 may be associated with susceptibility to autism. {ECO:0000269 PubMed:21264219}.

Relevant External Links for CXorf36

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CXorf36 Gene.

No data available for MalaCards and Genatlas for CXorf36 Gene

Publications for CXorf36 Gene

  1. Characterization of the deleted in autism 1 protein family: implications for studying cognitive disorders. (PMID: 21283809) Aziz A. … Bishop N.E. (PLoS ONE 2011) 2 3 67
  2. An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. (PMID: 11944989) Thiselton D.L. … Meindl A. (Genomics 2002) 2 3
  3. DIA1R is an X-linked gene related to Deleted In Autism-1. (PMID: 21264219) Aziz A. … Bishop N.E. (PLoS ONE 2011) 3
  4. A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PMID: 19377476) Tarpey P.S. … Stratton M.R. (Nat. Genet. 2009) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for CXorf36 Gene

Sources for CXorf36 Gene

Back to Top