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Aliases for CXorf21 Gene

Aliases for CXorf21 Gene

  • Chromosome X Open Reading Frame 21 2 3
  • 5430427O19Rik 3

External Ids for CXorf21 Gene

Previous GeneCards Identifiers for CXorf21 Gene

  • GC0XM029939
  • GC0XM030336
  • GC0XM030486
  • GC0XM028314

Summaries for CXorf21 Gene

GeneCards Summary for CXorf21 Gene

CXorf21 (Chromosome X Open Reading Frame 21) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXorf21 Gene

Genomics for CXorf21 Gene

Regulatory Elements for CXorf21 Gene

Genomic Location for CXorf21 Gene

30,558,824 bp from pter
30,577,916 bp from pter
19,093 bases
Minus strand

Genomic View for CXorf21 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CXorf21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CXorf21 Gene

Proteins for CXorf21 Gene

  • Protein details for CXorf21 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein CXorf21
    Protein Accession:

    Protein attributes for CXorf21 Gene

    301 amino acids
    Molecular mass:
    33894 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CXorf21 Gene

Proteomics data for CXorf21 Gene at MOPED

Post-translational modifications for CXorf21 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CXorf21 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CXorf21 Gene

Domains & Families for CXorf21 Gene

Protein Domains for CXorf21 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CXorf21: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CXorf21 Gene

Function for CXorf21 Gene

Phenotypes for CXorf21 Gene

GenomeRNAi human phenotypes for CXorf21:
genes like me logo Genes that share phenotypes with CXorf21: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CXorf21

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for CXorf21 Gene

Localization for CXorf21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CXorf21 Gene

Pathways & Interactions for CXorf21 Gene

SuperPathways for CXorf21 Gene

No Data Available

Interacting Proteins for CXorf21 Gene

Gene Ontology (GO) - Biological Process for CXorf21 Gene


No data available for Pathways by source and SIGNOR curated interactions for CXorf21 Gene

Drugs & Compounds for CXorf21 Gene

No Compound Related Data Available

Transcripts for CXorf21 Gene

mRNA/cDNA for CXorf21 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXorf21 Gene

Chromosome X open reading frame 21:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CXorf21

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CXorf21 Gene

No ASD Table

Relevant External Links for CXorf21 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CXorf21 Gene

mRNA expression in normal human tissues for CXorf21 Gene

mRNA differential expression in normal tissues according to GTEx for CXorf21 Gene

This gene is overexpressed in Whole Blood (x15.9).

SOURCE GeneReport for Unigene cluster for CXorf21 Gene Hs.665009

genes like me logo Genes that share expression patterns with CXorf21: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CXorf21 Gene

Orthologs for CXorf21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXorf21 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C9HXorf21 35
  • 86.47 (n)
  • 84.23 (a)
C9HXorf21 36
  • 84 (a)
(Canis familiaris)
Mammalia CXHXorf21 35
  • 88.96 (n)
  • 89.53 (a)
CXorf21 36
  • 88 (a)
(Mus musculus)
Mammalia 5430427O19Rik 35
  • 85.35 (n)
  • 84.23 (a)
5430427O19Rik 16
5430427O19Rik 36
  • 84 (a)
(Pan troglodytes)
Mammalia CXHXorf21 35
  • 99.56 (n)
  • 99.67 (a)
CXorf21 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1565785 35
  • 85.46 (n)
  • 84.23 (a)
(Monodelphis domestica)
Mammalia CXorf21 36
  • 68 (a)
(Gallus gallus)
Aves C1HXorf21 35
  • 63.99 (n)
  • 56.29 (a)
CXorf21 36
  • 54 (a)
(Anolis carolinensis)
Reptilia CXorf21 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490948 35
  • 55.82 (n)
  • 48.1 (a)
(Danio rerio)
Actinopterygii LOC796876 35
  • 50.16 (n)
  • 45.24 (a)
Species with no ortholog for CXorf21:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CXorf21 Gene

Gene Tree for CXorf21 (if available)
Gene Tree for CXorf21 (if available)

Paralogs for CXorf21 Gene Pseudogenes for CXorf21 Gene

genes like me logo Genes that share paralogs with CXorf21: view

No data available for Paralogs for CXorf21 Gene

Variants for CXorf21 Gene

Sequence variations from dbSNP and Humsavar for CXorf21 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs758625 -- 30,561,538(+) CCTGA(A/G)CTTGT intron-variant
rs758626 -- 30,561,955(+) CTACA(C/T)GGAAA intron-variant
rs887369 -- 30,559,729(+) TTCAG(A/C/T)ACTGC synonymous-codon, reference
rs1544544 -- 30,568,626(+) CACAC(C/T)CCAAG intron-variant
rs1544545 -- 30,568,646(+) ATTTA(A/T)CTTAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXorf21 Gene

Variant ID Type Subtype PubMed ID
nsv510532 CNV Loss 20534489

Variation tolerance for CXorf21 Gene

Residual Variation Intolerance Score: 61.98% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.21; 4.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CXorf21 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CXorf21 Gene

Disorders for CXorf21 Gene

Relevant External Links for CXorf21

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CXorf21: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CXorf21 Gene

Publications for CXorf21 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67

Products for CXorf21 Gene

Sources for CXorf21 Gene

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