Aliases for CXCR5 Gene
External Ids for CXCR5 Gene
Previous Symbols for CXCR5 Gene
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for CXCR5 Gene
CXCR5 (Chemokine (C-X-C Motif) Receptor 5) is a Protein Coding gene. Diseases associated with CXCR5 include burkitt lymphoma and chronic lymphocytic leukemia. Among its related pathways are Signaling by GPCR and Akt Signaling. GO annotations related to this gene include G-protein coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CCR7.
UniProtKB/Swiss-Prot for CXCR5 Gene
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation