CXCL6 Gene(Protein Coding)

C-X-C Motif Chemokine Ligand 6

GCID:: GC04P073837

GIFtS:: 59

Genes Participants

Aliases for CXCL6 Gene

C-X-C Motif Chemokine Ligand 6 ² ³
Granulocyte Chemotactic Protein 2 ² ³ ⁴
Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 6 (Granulocyte Chemotactic Protein 2) ² ³
Chemokine (C-X-C Motif) Ligand 6 (Granulocyte Chemotactic Protein 2) ² ³
Chemokine (C-X-C Motif) Ligand 6 ² ⁵
Small-Inducible Cytokine B6 ³ ⁴
Chemokine Alpha 3 ³ ⁴

SCYB6 ³ ⁴
CKA-3 ³ ⁴
GCP-2 ³ ⁴
GCP2 ³ ⁴
Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member B ³

External Ids for CXCL6 Gene

HGNC: 10643
Entrez Gene: 6372
Ensembl: ENSG00000124875
OMIM: 138965
UniProtKB: P80162

Previous HGNC Symbols for CXCL6 Gene

SCYB6

Previous GeneCards Identifiers for CXCL6 Gene

GC04P074691
GC04P074942
GC04P075102
GC04P075168
GC04P075067
GC04P074921
GC04P070513

Export aliases for CXCL6 gene to outside databases

Summaries for CXCL6 Gene

GeneCards Summary for CXCL6 Gene

CXCL6 (C-X-C Motif Chemokine Ligand 6) is a Protein Coding gene. Diseases associated with CXCL6 include Tonsillitis and Mastitis. Among its related pathways are Peptide ligand-binding receptors and ERK Signaling. GO annotations related to this gene include heparin binding and CXCR chemokine receptor binding. An important paralog of this gene is PF4.

UniProtKB/Swiss-Prot for CXCL6 Gene

CXCL6_HUMAN,P80162

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CXCL6 Gene

Genomics for CXCL6 Gene

Regulatory Elements for CXCL6 Gene

Enhancers for CXCL6 Gene

GeneHancer Identifier	Score	Enhancer Sources	TSS distance (kb)	Number of Genes Away	Size (kb)	Transcription Factor Binding Sites within enhancer	Other Gene Targets for Enhancer

Enhancers around CXCL6 on UCSC Golden Path with GeneCards custom track

Promoters for CXCL6 Gene

Ensembl Regulatory Elements (ENSRs)	TSS Distance (bp)	Size (bp)	Binding Sites for Transcription Factors within promoters

ENSRs around CXCL6 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the CXCL6 gene promoter:

See All at QIAGEN

Regulatory Element Products

Genomic Location for CXCL6 Gene

Chromosome:: 4

Start:: 73,836,497 bp from pter
End:: 73,849,064 bp from pter

Size:: 12,568 bases
Orientation:: Plus strand

Genomic View for CXCL6 Gene

Genes around CXCL6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:

4q13.3 by Ensembl
4q13.3 by Entrez Gene
4q13.3 by HGNC

CXCL6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

Genomic Location for CXCL6 Gene — Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CXCL6 Gene

Proteins for CXCL6 Gene

Protein details for CXCL6 Gene (UniProtKB/Swiss-Prot)
Protein Symbol:

P80162-CXCL6_HUMAN

Recommended name:

C-X-C motif chemokine 6

Protein Accession:

P80162

Secondary Accessions:
- B2R4X3
- Q4W5D4
Protein attributes for CXCL6 Gene

Size:

114 amino acids

Molecular mass:

11897 Da

Quaternary structure:

No Data Available

neXtProt entry for CXCL6 Gene

Proteomics data for CXCL6 Gene at MOPED

Protein Expression for CXCL6 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for CXCL6 Gene

Modification sites at PhosphoSitePlus
- P80162
Modification sites at neXtProt
- NX_P80162

Other Protein References for CXCL6 Gene

ENSEMBL proteins:

REFSEQ proteins:

NP_002984.1

Antibody Products

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies

R&D Systems Antibodies for CXCL6 (CXCL6/GCP-2)

OriGene Antibodies for CXCL6
Custom Antibody Services

Novus Biologicals Antibodies for CXCL6

Abcam antibodies for GCP2

Cloud-Clone Corp. Antibodies for CXCL6

Invitrogen Antibodies for CXCL6

antibodies-online Antibodies for CXCL6: See all 29

GeneTex CXCL6 antibody for CXCL6

Santa Cruz Biotechnology (SCBT) Antibodies for CXCL6

Protein Products

Browse Purified and Recombinant Proteins at EMD Millipore

R&D Systems Proteins and Enzymes for CXCL6 (CXCL6/GCP-2)

Browse Enzo Life Sciences for proteins

OriGene Purified Proteins for CXCL6
Search Origene for MassSpec and Protein Over-expression Lysates for CXCL6
Origene Custom Protein Services for CXCL6

GenScript Custom Purified and Recombinant Proteins Services for CXCL6

Novus Biologicals lysates and proteins for CXCL6

Browse ProSpec Recombinant Proteins

Cloud-Clone Corp. Proteins for CXCL6
- RPB570Hu01

Search eBioscience for CXCL6 related proteins

GeneTex GCP-2 Recombinant Protein (Active) (GTX48141-PRO) for CXCL6

Abcam proteins for GCP2

Assay Products

Browse Kits and Assays available from EMD Millipore

OriGene ELISA Kits for CXCL6
- EA100234
Custom Assay Services

R&D Systems ELISAs, Luminex Assays, and other biochemical assays for CXCL6 (CXCL6/GCP-2)

GenScript Custom Assay Services for CXCL6

Browse Enzo Life Sciences for kits & assays

Cloud-Clone Corp Assay Kits for CXCL6
- SEB570Hu
- SCB570Hu

Search eBioscience for CXCL6 related elisas

antibodies-online Kits for CXCL6: See all 41

Search for Assays for CXCL6 at Abcam

No data available for DME Specific Peptides for CXCL6 Gene

Domains & Families for CXCL6 Gene

Gene Families for CXCL6 Gene

HGNC:

Protein Domains for CXCL6 Gene

InterPro:

Blocks:

Interleukin-8 signature

ProtoNet:

P80162

Suggested Antigen Peptide Sequences for CXCL6 Gene

GenScript: Design optimal peptide antigens:

Small-inducible cytokine B6 (CXCL6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P80162

UniProtKB/Swiss-Prot:

CXCL6_HUMAN :

Belongs to the intercrine alpha (chemokine CxC) family.

Family:

Belongs to the intercrine alpha (chemokine CxC) family.

Function for CXCL6 Gene

Molecular function for CXCL6 Gene

UniProtKB/Swiss-Prot Function:

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

CXCL6_HUMAN,P80162

Gene Ontology (GO) - Molecular Function for CXCL6 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0045236	CXCR chemokine receptor binding	IBA	--

Phenotypes for CXCL6 Gene

MGI mutant phenotypes for CXCL6:

inferred from 2 alleles

GenomeRNAi human phenotypes for CXCL6:

Animal Models for CXCL6 Gene

MGI Knock Outs for CXCL6:

Cxcl5 ^tm1.1Mkch
Cxcl5 ^tm1Gscw

Animal Model Products

Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study

ViGene Biosciences lentiviral particle packaged cDNA for CXCL6 gene
- LH830352
ViGene Biosciences ready-to-package AAV shRNAs for CXCL6 gene
- SH830352
Search ViGene Biosciences for CXCL6

CRISPR Products

OriGene CRISPR knockouts for CXCL6
- KN204573

Santa Cruz Biotechnology (SCBT) CRISPR for CXCL6

GenScript: Design CRISPR guide RNA sequences for CXCL6

miRNA for CXCL6 Gene

miRTarBase miRNAs that target CXCL6

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CXCL6 Gene

Localization for CXCL6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CXCL6 Gene

Secreted.

P80162-CXCL6_HUMAN

Subcellular locations from

COMPARTMENTS

Jensen Localization Image for CXCL6 Gene

Compartment	Confidence
extracellular	5
cytoskeleton	1

No data available for Gene Ontology (GO) - Cellular Components for CXCL6 Gene

Pathways & Interactions for CXCL6 Gene

SuperPathways for CXCL6 Gene

More details on SuperPathways for CXCL6

	Superpath	Contained pathways
1	PEDF Induced Signaling	MIF Mediated Glucocorticoid Regulation .94 MIF Regulation of Innate Immune Cells .94 PEDF Induced Signaling .73 all-trans-Retinoic Acid Signaling in Brain .71 RAR-Gamma-RXR-Alpha Degradation .62	IL-6 Pathway .61 STAT3 Pathway .47 Endothelin-1 Signaling Pathway .46 Cytokine-cytokine receptor interaction .43
2	Peptide ligand-binding receptors	Class A/1 (Rhodopsin-like receptors) .72 GPCR ligand binding .72	Peptide ligand-binding receptors .60 G alpha (i) signalling events .43
3	ERK Signaling	ERK Signaling .61 Rho Family GTPases .61	Molecular Mechanisms of Cancer .51
4	Signaling by GPCR	GPCR downstream signaling .76 Signaling by GPCR .76	Signal Transduction .52
5	Chemokine Signaling	Chemokine signaling pathway .33	Chemokine Signaling .33

Pathways by source for CXCL6 Gene

8 Reactome pathways for CXCL6 Gene

4 KEGG pathways for CXCL6 Gene

2 GeneGo (Thomson Reuters) pathways for CXCL6 Gene

1 R&D Systems pathway for CXCL6 Gene

Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions

17 Qiagen pathways for CXCL6 Gene

Interacting Proteins for CXCL6 Gene

http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000226317%0d%0a9606.ENSP00000330070%0d%0a9606.ENSP00000286758%0d%0a9606.ENSP00000355316%0d%0a9606.ENSP00000351671%0d%0a9606.ENSP00000397181%0d%0a — STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins: ENSP00000226317 P80162-CXCL6_HUMAN for CXCL6 Gene via STRING I2D

Symbol	External ID(s)	Details
CXCR1	ENSP00000295683 ²⁰ P25024 ²¹	STRING: ENSP00000295683 I2D: score=2
CXCR2	ENSP00000319635 ²⁰ P25025 ²¹	STRING: ENSP00000319635 I2D: score=2
MMP9	ENSP00000361405 ²⁰ P14780 ²¹	STRING: ENSP00000361405 I2D: score=2
ACKR3	ENSP00000272928 ²⁰	STRING: ENSP00000272928
ADCY1	ENSP00000297323 ²⁰	STRING: ENSP00000297323

Gene Ontology (GO) - Biological Process for CXCL6 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002690	positive regulation of leukocyte chemotaxis	IBA	--
GO:0006935	chemotaxis	TAS	9164944
GO:0006955	immune response	IEA,IBA	--
GO:0007186	G-protein coupled receptor signaling pathway	IBA	--
GO:0007267	cell-cell signaling	TAS	9164944

No data available for SIGNOR curated interactions for CXCL6 Gene

Drugs & Compounds for CXCL6 Gene

(2) Drugs for CXCL6 Gene - From: Novoseek

Name	Status	Disease Links	Group	Role	Mechanism of Action	Clinical Trials

(6) Additional Compounds for CXCL6 Gene - From: Novoseek

Name	Synonyms	Role	CAS Number	PubChem IDs	PubMed IDs

Drug Products

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CXCL6

Browse compounds at ApexBio

Transcripts for CXCL6 Gene

mRNA/cDNA for CXCL6 Gene

(1) REFSEQ mRNAs :

NM_002993.3

(4) Additional mRNA sequences :

(59) Selected AceView cDNA sequences:

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CXCL6 Gene

Chemokine (C-X-C motif) ligand 6:

Hs.164021

Representative Sequences:

NM_002993

CRISPR Products

OriGene CRISPR knockouts for CXCL6
- KN204573

Santa Cruz Biotechnology (SCBT) CRISPR for CXCL6

GenScript: Design CRISPR guide RNA sequences for CXCL6

miRNA Products

Search ViGene Biosciences for CXCL6

SwitchGear CXCL6 3' UTR sequence
Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhibitory RNA Products

Origene shRNA, rat_shrna, siRNA, and RNAi products in human, mouse, rat for CXCL6
Browse OriGene Inhibitory RNA Products For CXCL6

ViGene Biosciences ready-to-package AAV shRNAs for CXCL6 gene
- SH830352

Search Santa Cruz Biotechnology (SCBT) for CXCL6 siRNA/shRNA

Clone Products

OriGene clones in human for CXCL6
OriGene ORF clones in human,rat for CXCL6
Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling

GenScript: Next-day shipping cDNA clones in your preferred vector
- NM_002993

Sino Biological Human cDNA Clone for CXCL6

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat

Search Addgene for plasmids for CXCL6

Flow Cytometry Products

eBioscience FlowRNA Probe Sets

Alternative Splicing Database (ASD) splice patterns (SP) for CXCL6 Gene

No ASD Table

Relevant External Links for CXCL6 Gene

GeneLoc Exon Structure for: CXCL6
ECgene alternative splicing isoforms for: CXCL6

Expression for CXCL6 Gene

mRNA expression in normal human tissues for CXCL6 Gene

mRNA expression by BioGPS for CXCL6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Neural Crest (Gastrulation Derivatives)
Inner Cell Mass (Early Embryonic Tissues)
- Line H9 (WA09)
- Human embryonic stem cells (family)
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
Heart (Cardiovascular System)
- Mature Cardiac Fibroblasts Myocardium
Fibroblasts
- Mature Cardiac Fibroblasts Myocardium
Liver (Hepatobiliary System)
- Liver Lobule
Paraxial Mesoderm (Gastrulation Derivatives)
- PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
Mesoderm (Gastrulation Derivatives)
- PureStem 7SMOO32, NCr-fac & Meso Progenitor
Spleen (Hematopoietic System)
Smooth Muscle (Muscoskeletal System)

mRNA differential expression in normal tissues according to GTEx for CXCL6 Gene

This gene is overexpressed in Spleen (x21.1).

Protein differential expression in normal tissues from HIPED for CXCL6 Gene

This gene is overexpressed in Islet of Langerhans (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CXCL6 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CXCL6 Gene

Integrated proteomics: cell line protein expression from ProteomicsDB, MOPED and MaxQB for CXCL6 Gene

SOURCE GeneReport for Unigene cluster for CXCL6 Gene Hs.164021

Protein tissue co-expression partners for CXCL6 Gene

Primer Products

OriGene qPCR primer pairs and template standards for CXCL6
- HK202329
OriGene qPCR primer pairs for CXCL6
- HP206597

No data available for mRNA Expression by UniProt/SwissProt for CXCL6 Gene

Orthologs for CXCL6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CXCL6 Gene

Organism	Taxonomy	Gene	Similarity	Type	Details
mouse (Mus musculus)	Mammalia	Cxcl5 ³⁵	71.43 (n) 64.94 (a)		20311 NM_009141.3 NP_033167.2
		Cxcl5 ¹⁶			90759360
		Cxcl5 ³⁶	51 (a)	OneToMany	5:90759299-90761625
chimpanzee (Pan troglodytes)	Mammalia	CXCL6 ³⁵	98.83 (n) 96.49 (a)		740729 XM_001156255.3 XP_001156255.1
chimpanzee (Pan troglodytes)	Mammalia	CXCL6 ³⁶	96 (a)	OneToOne	4:56239096-56241309
rat (Rattus norvegicus)	Mammalia	Cxcl5 ³⁵	69.3 (n) 59.65 (a)		60665 NM_022214.1 NP_071550.1
cow (Bos Taurus)	Mammalia	CXCL6 ³⁶	74 (a)	OneToMany	6:90645964-90648076
dog (Canis familiaris)	Mammalia	-- ³⁶	60 (a)	OneToMany	13:62514259-62515981
oppossum (Monodelphis domestica)	Mammalia	-- ³⁶	40 (a)	OneToMany	5:21327456-21330596
platypus (Ornithorhynchus anatinus)	Mammalia	-- ³⁶	43 (a)	ManyToMany	Contig34660:3809-5082
		-- ³⁶	48 (a)	ManyToMany	Ultra362:665218-670940
		-- ³⁶	37 (a)	ManyToMany	Ultra362:672498-717966
chicken (Gallus gallus)	Aves	-- ³⁶	33 (a)	OneToMany	4:50379773-50381069
lizard (Anolis carolinensis)	Reptilia	-- ³⁶	37 (a)	OneToMany	6:60123888-60134622

Species with no ortholog for CXCL6:

A. gosspyii yeast (Ashbya gossypii)
Actinobacteria (Mycobacterium tuberculosis)
African clawed frog (Xenopus laevis)
African malaria mosquito (Anopheles gambiae)
Alicante grape (Vitis vinifera)
alpha proteobacteria (Wolbachia pipientis)
amoeba (Dictyostelium discoideum)
Archea (Pyrococcus horikoshii)
baker's yeast (Saccharomyces cerevisiae)
barley (Hordeum vulgare)
beta proteobacteria (Neisseria meningitidis)
bread mold (Neurospora crassa)
Chromalveolata (Phytophthora infestans)
common water flea (Daphnia pulex)
corn (Zea mays)
E. coli (Escherichia coli)
filamentous fungi (Aspergillus nidulans)
Firmicute bacteria (Streptococcus pneumoniae)
fission yeast (Schizosaccharomyces pombe)
fruit fly (Drosophila melanogaster)
green algae (Chlamydomonas reinhardtii)
honey bee (Apis mellifera)
K. lactis yeast (Kluyveromyces lactis)
loblloly pine (Pinus taeda)
malaria parasite (Plasmodium falciparum)
medicago trunc (Medicago Truncatula)
moss (Physcomitrella patens)
orangutan (Pongo pygmaeus)
pig (Sus scrofa)
rainbow trout (Oncorhynchus mykiss)
rice (Oryza sativa)
rice blast fungus (Magnaporthe grisea)
schistosome parasite (Schistosoma mansoni)
sea anemone (Nematostella vectensis)
sea squirt (Ciona intestinalis)
sea squirt (Ciona savignyi)
sea urchin (Strongylocentrotus purpuratus)
sorghum (Sorghum bicolor)
soybean (Glycine max)
stem rust fungus (Puccinia graminis)
sugarcane (Saccharum officinarum)
thale cress (Arabidopsis thaliana)
tomato (Lycopersicon esculentum)
toxoplasmosis (Toxoplasma gondii)
Trichoplax (Trichoplax adhaerens)
tropical clawed frog (Silurana tropicalis)
wheat (Triticum aestivum)
worm (Caenorhabditis elegans)
zebrafish (Danio rerio)

Evolution for CXCL6 Gene

ENSEMBL:: Gene Tree for CXCL6 (if available)
TreeFam:: Gene Tree for CXCL6 (if available)

Paralogs for CXCL6 Gene

PF4 ⁵
CXCL1 ⁵
CXCL3 ⁵
PF4V1 ⁵
CXCL2 ⁵
CXCL8 ⁵
CXCL5 ⁵
PPBP ⁵

(12) SIMAP similar genes for CXCL6 Gene using alignment to 2 proteins:

Variants for CXCL6 Gene

Sequence variations from dbSNP and Humsavar for CXCL6 Gene

SNP ID	Clin	Chr 04 pos	Sequence Context	Type
rs1951243	--	73,836,413(+)	ACCCT(C/G)CTGAA	upstream-variant-2KB
rs1957077	--	73,838,574(+)	ATATA(C/T)AGCAT	utr-variant-3-prime
rs1957078	--	73,838,865(+)	TCATT(A/C)CCCAA	downstream-variant-500B
rs1957079	--	73,839,080(+)	TCATC(A/G)GTACT	downstream-variant-500B
rs4417936	--	73,837,134(+)	ACTTA(A/G)GCAAG	intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CXCL6 Gene

Variant ID	Type	Subtype	PubMed ID
nsv4389	CNV	Insertion	18451855

Variation tolerance for CXCL6 Gene

Residual Variation Intolerance Score: 43.4% of all genes are more intolerant (likely to be disease-causing)

Gene Damage Index Score: 1.14; 23.04% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CXCL6 Gene

Disorders for CXCL6 Gene

(4) MalaCards diseases for CXCL6 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder	Aliases	PubMed IDs
tonsillitis	chronic tonsillitis	15807854
mastitis	breast inflammation
rheumatoid arthritis	rheumatoid arthritis, progression of	14707104
acute endometritis

- elite association - COSMIC cancer census association via MalaCards

Search CXCL6 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CXCL6

Genetic Association Database (GAD): CXCL6
Human Genome Epidemiology (HuGE) Navigator: CXCL6
Atlas of Genetics and Cytogenetics in Oncology and Haematology:: CXCL6

Export disorders for CXCL6 gene to outside databases

No data available for UniProtKB/Swiss-Prot and Genatlas for CXCL6 Gene

Publications for CXCL6 Gene

Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell- derived neutrophil activating peptide-78 mRNAs. (PMID: 9057843) Froyen G. … Billiau A. (Eur. J. Biochem. 1997) ³ ⁴ ²³ ⁶⁷
Granulocyte chemotactic protein 2 (gcp-2/cxcl6) complements interleukin-8 in periodontal disease. (PMID: 18842116) Kebschull M. … Papapanou P.N. (J. Periodont. Res. 2009) ³ ²³
Gonadotropin-releasing hormone-regulated chemokine expression in human placentation. (PMID: 19369450) Cavanagh P.C. … Babwah A.V. (Am. J. Physiol., Cell Physiol. 2009) ³ ²³
The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial. (PMID: 18443119) Linge H.M. … Egesten A. (Antimicrob. Agents Chemother. 2008) ³ ²³
CXCL6 (granulocyte chemotactic protein-2): a novel chemokine involved in the innate immune response of the amniotic cavity. (PMID: 18782286) Mittal P. … Hassan S.S. (Am. J. Reprod. Immunol. 2008) ³ ²³