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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CXCL5 Gene

protein-coding GIFtS: 61
GCID: GC04M074851

chemokine (C-X-C motif) ligand 5

(Previous names: small inducible cytokine subfamily B (Cys-X-Cys), member...)
(Previous symbol: SCYB5)

Explore 67 diseases affiliated with
CXCL5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Chemokine (C-X-C Motif) Ligand 5¹ ²		ENA-78(1-78)² ³
SCYB5¹ ² ³ ⁵		ENA78³ ⁵
ENA-78¹ ²		C-X-C Motif Chemokine 5²
Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 5 (Epithelial-Derived Neutrophil-Activating Peptide 78)¹ ²		Epithelial-Derived Neutrophil Activating Protein 78²
Epithelial-Derived Neutrophil-Activating Protein 78² ³		Epithelial-Derived Neutrophil-Activating Peptide 78²
Neutrophil-Activating Peptide ENA-78² ³		Neutrophil-Activating Protein 78²
Small-Inducible Cytokine B5² ³		Small Inducible Cytokine B5²

External Ids:	HGNC: 10642¹	Entrez Gene: 6374²	Ensembl: ENSG00000163735⁷	OMIM: 600324⁵	UniProtKB: P42830³

Export aliases for CXCL5 gene to outside databases

Previous GC identifers: GC04M075100 GC04M075263 GC04M075328 GC04M075327 GC04M075226 GC04M070672

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CXCL5:

The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine

is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor

necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. (provided by

RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CXCL5_HUMAN, P42830

Function: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher

chemotactic activity for neutrophil granulocytes

Gene Wiki entry for CXCL5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_022778.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CXCL5 gene promoter:
HEN1 AML1a HNF-3beta Meis-1b GATA-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CXCL5 promoter sequence

Search SABiosciences Chromatin IP Primers for CXCL5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXCL5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3 Ensembl cytogenetic band: 4q13.3 HGNC cytogenetic band: 4q13.3

CXCL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CXCL5 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M074851: view genomic region (about GC identifiers)

Start:	74,861,359 bp from pter	End:	74,864,496 bp from pter
Size:	3,138 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CXCL5_HUMAN, P42830 (See protein sequence)

Recommended Name: C-X-C motif chemokine 5 precursor

Size: 114 amino acids; 11972 Da

Subcellular location: Secreted

Secondary accessions: Q96QE1

Explore the universe of human proteins at neXtProt for CXCL5: NX_P42830

Post-translational modifications:

N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from

peripheral blood monocytes¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P42830

CXCL5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_002985.1

ENSEMBL proteins:

ENSP00000296027

Reactome Protein details: P42830
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	ProSpec Recombinant Protein for CXCL5
	Uscn Proteins for CXCL5

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005615	extracellular space	IEA	--

CXCL5 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CXCL5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CXCL5 for domains About GeneDecksing

3 InterPro domains/families:

IPR001811 Chemokine_IL8-like_dom

IPR001089 Chemokine_CXC

IPR018048 Chemokine_CXC_CS

Graphical View of Domain Structure for InterPro Entry P42830

ProtoNet protein and cluster: P42830

1 Blocks protein family: IPB002473 Interleukin-8 signature

UniProtKB/Swiss-Prot: CXCL5_HUMAN, P42830

Similarity: Belongs to the intercrine alpha (chemokine CxC) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CXCL5_HUMAN, P42830

Function: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher

chemotactic activity for neutrophil granulocytes

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		hsa-miR-3163 hsa-miR-577 hsa-miR-576-5p hsa-miR-1323 hsa-miR-4263 hsa-miR-548o hsa-miR-138-2*
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXCL5

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008009	chemokine activity	IEA	--

CXCL5 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

PEDF Induced Signaling

8/9 pathways (see all 9)
PEDF Induced Signaling	1.00	RAR-Gamma-RXR-Alpha Degradation	0.54
MIF Mediated Glucocorticoid Regulation	0.73	STAT3 Pathway	0.47
MIF Regulation of Innate Immune Cells	0.71	Endothelin-1 Signaling Pathway	0.44
IL-6 Pathway	0.61	Cytokine-cytokine receptor interaction	0.26

Class A/1 (Rhodopsin-like receptors)

	Class A/1 (Rhodopsin-like receptors)	1.00			Peptide ligand-binding receptors	0.61
	GPCR ligand binding	0.75			G alpha (i) signalling events	0.44

Rho Family GTPases

	Rho Family GTPases	1.00			Molecular Mechanisms of Cancer	0.51
	ERK Signaling	0.61

Signaling by GPCR

	Signaling by GPCR	1.00			Signal Transduction	0.56
	GPCR downstream signaling	0.89

PAK Pathway

PAK Pathway

1.00

Antioxidant Action of Vitamin-C

0.56

Pathway sources
See GeneCards unified pathways
Show all pathways

5/17 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CXCL5 (see all 17)

	Endothelin-1 Signaling Pathway
	Molecular Mechanisms of Cancer
	Antioxidant Action of Vitamin-C
	Transendothelial Migration of Leukocytes
	MIF Mediated Glucocorticoid Regulation

5/8 Reactome Pathways for CXCL5 (see all 8)

	GPCR downstream signaling
	Peptide ligand-binding receptors
	Chemokine receptors bind chemokines
	Signal Transduction
	Signaling by GPCR

4 Kegg Pathways (Kegg details for CXCL5):

	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Pertussis
	Rheumatoid arthritis

CXCL5 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CXCL5

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/157 Interacting proteins for CXCL5 (P42830³ ENSP00000296027⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 157)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CXCR2	P25025³, ENSP00000319635⁴	I2D: score=3 STRING: ENSP00000319635
MMP9	P14780³, ENSP00000361405⁴	I2D: score=3 STRING: ENSP00000361405
CXCR1	P25024³, ENSP00000295683⁴	I2D: score=3 STRING: ENSP00000295683
DARC	Q16570³, ENSP00000357103⁴	I2D: score=2 STRING: ENSP00000357103
MMP1	P03956³	I2D: score=1

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006935	chemotaxis	TAS	10820279
GO:0006955	immune response	IEA	--
GO:0007165	signal transduction	TAS	10820279
GO:0007267	cell-cell signaling	TAS	7929219
GO:0008284	positive regulation of cell proliferation	TAS	10463948

CXCL5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CXCL5 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CXCL5
10/23 Novoseek chemical compound relationships for CXCL5 gene (see all 23) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
groalpha	92.4	32	10540194 (4), 16869002 (4), 11950713 (2), 10513809 (2) (see all 18)
grogamma	89.7	12	8702798 (5), 9553055 (2), 9054580 (1), 9688939 (1) (see all 5)
ena 78	89.3	4	17444857 (2), 9064356 (1), 11503269 (1)
grobeta	85.4	11	8702798 (5), 9553055 (2), 9688939 (1), 19594487 (1)
rantes	83.6	68	16869002 (4), 17456632 (3), 15899984 (3), 16635746 (2) (see all 42)
ppbp	73.1	3	10343098 (1), 9465307 (1)
tarc	54	1	11533168 (1)
fmlp	46.2	6	10820279 (2), 16873675 (2), 14662891 (1), 8810307 (1)
ccl3	45.2	3	12851650 (1), 18565769 (1)
vegf	34.5	13	20137269 (3), 19281539 (2), 16377203 (1), 15860217 (1) (see all 7)

Search CenterWatch for drugs/clinical trials and news about CXCL5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CXCL5 gene:

NM_002994.3

Unigene Cluster for CXCL5:

Chemokine (C-X-C motif) ligand 5

Hs.89714 [show with all ESTs]

Unigene Representative Sequence: NM_002994

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000296027(uc003hhk.3)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CXCL5
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate CXCL5:
		hsa-miR-3163 hsa-miR-577 hsa-miR-576-5p hsa-miR-1323 hsa-miR-4263 hsa-miR-548o hsa-miR-138-2*
		SwitchGear 3'UTR luciferase reporter plasmid: CXCL5 3' UTR sequence

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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CXCL5 OriGene shRNA RFP: CXCL5 OriGene siRNA: CXCL5
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Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CXCL5 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CXCL5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Additional cDNA sequence:

AK026546.1 AK312128.1 BC008376.1 BT006807.1 CR457428.1 X78686.1

2 DOTS entries:

DT.97854572 DT.100798582

24/135 AceView cDNA sequences (see all 135):

CD366359 CB243459 CD367085 CA308153 BU626570 CA434519 CN480795 CD367021

BM990320 CD366221 BM756990 CA306518 CD369768 AW471084 CA306404 BQ001520

CB529040 CD364917 CA308675 CD368286 CB529064 CA306582 BM832290 CD366914

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CXCL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAAGTTTC

About this image

CXCL5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

Bone marrow-derived mesenchymal stem cells (Stempeucel) (Adult Stem / Progenitor Cell)

Bone

PureStem™ progenitor E44 (Embryonic Progenitor Cell)

Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CXCL5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CXCL5

SOURCE GeneReport for Unigene cluster: Hs.89714

SABiosciences Expression via Pathway-Focused PCR Arrays including CXCL5 (see all 9):

Angiogenic Growth Factors in human mouse rat

Wound Healing in human mouse rat

Inflammatory Response & Autoimmunity in human mouse rat

Angiogenesis in human mouse rat

Inflammatory Response & Autoimmunity 384HT in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CXCL5 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXCL5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CXCL5 gene from 1/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	--	Uncharacterized protein	27(a)	1 → many	4(52472071-52473367)

ENSEMBL Gene Tree for CXCL5 (if available)
TreeFam Gene Tree for CXCL5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CXCL5 gene

CXCL3² PPBP² PF4² CXCL1² PF4V1² IL8² CXCL2² CXCL6²

11 SIMAP similar genes for CXCL5 using alignment to 2 protein entries: CXCL5_HUMAN (see all proteins):

CXCL6 PPBP IL8 CXCL1 CXCL2 CXCL3

PF4 CXCL9 PF4V1 CXCL10 CXCL13

CXCL5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

Human Gene Mutation Database (HGMD): CXCL5

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXCL5

DNA2.0 Custom Variant and Variant Library Synthesis for CXCL5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CXCL5 for disorders           About GeneDecksing

OMIM gene information: 600324    OMIM disorders: --

20/67 diseases for CXCL5 (see all 67):    About MalaCards

hemolytic-uremic syndrome nonspecific interstitial pneumonia abdominal aortic aneurysm non-hodgkin lymphoma

severe acute respiratory syndrome aortic aneurysm inflammatory bowel disease chronic obstructive pulmonary disease

idiopathic pulmonary fibrosis klebsiella bacterial meningitis sarcoidosis

reactive arthritis hodgkin's lymphoma pulmonary fibrosis interstitial lung disease

pulmonary emphysema rheumatoid arthritis pulmonary sarcoidosis emphysema

1 disease from the University of Copenhagen DISEASES database for CXCL5:

Lung disease

10/30 Novoseek disease relationships for CXCL5 gene (see all 30) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
fibrosis idiopathic pulmonary	59.5	7	20137269 (2), 16085216 (2), 11751193 (1), 19117745 (1)
inflammation	50.6	15	18769620 (3), 11046061 (1), 9553055 (1), 9620668 (1) (see all 8)
bronchoalveolar lavage fluid	45.3	4	8810593 (1), 16085216 (1), 18644457 (1), 14662873 (1)
necrosis	43.8	18	16553183 (2), 1744577 (1), 8083342 (1), 12972516 (1) (see all 15)
rheumatoid arthritis	39	6	9365115 (1), 10358204 (1), 18576313 (1), 9232436 (1) (see all 5)
pneumonitis hypersensitivity	35.8	1	19117745 (1)
colitis ulcerative	34.9	9	9252512 (4), 10535602 (1), 9365115 (1), 11559712 (1) (see all 6)
endometriosis	34.3	25	12620496 (5), 15837658 (5), 14967364 (4), 16553183 (3) (see all 5)
sarcoidosis pulmonary	31.1	3	17052298 (3)
sarcoidosis	23.9	5	17052298 (2), 19117745 (1), 17035428 (1)

Human Genome Epidemiology (HuGE) Navigator: CXCL5 (13 documents)

Export disorders for CXCL5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CXCL5 gene, integrated from 9 sources (see all 256):
(articles sorted by number of sources associating them with CXCL5)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene. (PubMed id 7929219)^{1, 2, 3, 9} Chang M.S.... Simonet S. (1994)
Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. (PubMed id 1744577)^{1, 2, 9} Walz A....Strieter R.M. (1991)
Characterization of the gene for human neutrophil-activating peptide 78 (ENA-78). (PubMed id 7999089)^{1, 2, 9} Corbett M.S.... Walz A. (1994)
Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms. (PubMed id 10095777)^{1, 2, 9} Wuyts A.... Van Damme J. (1999)
Cloning of a full-length cDNA encoding the neutrophil-activating peptide ENA-78 from human platelets. (PubMed id 7828901)^{1, 2, 9} Power C.A.... Wells T.N.C. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Regulation of the immune response by the interaction of chemokines and proteases. (PubMed id 14711052)^{1, 2} Struyf S.... Van Damme J. (2003)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{1, 2} Gevaert K.... Vandekerckhove J. (2003)
Localization of distal regulatory domains in the megakaryocyte- specific platelet basic protein/platelet factor 4 gene locus. (PubMed id 11468158)^{1, 2} Zhang C.... Reilly M.P. (2001)
CXCL5 gene polymorphisms are related to systemic concentrations and leukocyte production of epithelial neutrophil-activating peptide (ENA-78). (PubMed id 16567110)^{1, 9} Zineh I....Schofield R.S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 6374	HGNC: 10642	AceView: CXCL5	Ensembl:ENSG00000163735	euGenes: HUgn6374
ECgene: CXCL5	Kegg: 6374	H-InvDB: CXCL5

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CXCL5	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CXCL5	Genetics and Cytogenetics in Oncology and Haematology
Wikipedia	http://en.wikipedia.org/wiki/CXCL5

Intellectual Property for CXCL5 gene
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Patent Information for CXCL5 gene:
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chemokine (C-X-C motif) ligand 5

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chemokine (C-X-C motif) ligand 5

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