Aliases for CXCL16 Gene
External Ids for CXCL16 Gene
Previous GeneCards Identifiers for CXCL16 Gene
GeneCards Summary for CXCL16 Gene
CXCL16 (C-X-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CXCL16 include Xanthogranulomatous Cholecystitis. Among its related pathways are Peptide ligand-binding receptors and ERK Signaling. GO annotations related to this gene include chemokine activity and low-density lipoprotein receptor activity.
UniProtKB/Swiss-Prot for CXCL16 Gene
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.