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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CXCL11 Gene

protein-coding   GIFtS: 62
GCID: GC04M076954

chemokine (C-X-C motif) ligand 11

(Previous names: small inducible cytokine subfamily B (Cys-X-Cys), member...)
(Previous symbols: SCYB9B, SCYB11)
 Explore 61 diseases affiliated with
CXCL11 via our new
 Human Malady Compendium 
Biological research products
for CXCL11
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-X-C Motif) Ligand 111 2     Interferon-Inducible T-Cell Alpha Chemoattractant2 3
SCYB111 2 3 5     Small-Inducible Cytokine B112 3
SCYB9B1 2 3 5     IP92 5
H1741 2 3     Beta-R13
I-TAC1 2 3     C-X-C Motif Chemokine 112
IP-91 2 3     Small Inducible Cytokine B112
B-R11     Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 9B2
Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 111 2     Beta-R13
Interferon Gamma-Inducible Protein 92 3     ITAC3

External Ids:    HGNC: 106381   Entrez Gene: 63732   Ensembl: ENSG000001692487   OMIM: 6048525   UniProtKB: O146253   

Export aliases for CXCL11 gene to outside databases

Previous GC identifers: GC04M076850 GC04M077145 GC04M077347 GC04M077413 GC04M077312 GC04M072707


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CXCL11:
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate
cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G
protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the
immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved
in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member
of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the
dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation
signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of
this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CXL11_HUMAN, O14625
Function: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces
calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell
recruitment. May play a role in skin immune responses

Gene Wiki entry for CXCL11


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CXCL11 gene promoter:
         AML1a   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCXCL11 promoter sequence
   Search SABiosciences Chromatin IP Primers for CXCL11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CXCL11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.2   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21

CXCL11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CXCL11 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M076954:  view genomic region     (about GC identifiers)

Start:
76,954,835 bp from pter      End:
76,962,568 bp from pter
Size:
7,734 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CXL11_HUMAN, O14625 (See protein sequence)
Recommended Name: C-X-C motif chemokine 11 precursor  
Size: 94 amino acids; 10365 Da
Subcellular location: Secreted
Mass spectrometry: Mass=8303; Method=MALDI; Range=22-94; Source=PubMed:10233762;
Sequence caution: Sequence=AAB17374.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CXCL11:
1RJT (3D)    
Secondary accessions: Q53YA3 Q92840

Explore the universe of human proteins at neXtProt for CXCL11: NX_O14625

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14625

  • CXCL11 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005400.1  
    ENSEMBL proteins: 
     ENSP00000306884   ENSP00000425819  
    Reactome Protein details: O14625
    Human Recombinant Protein Products: 
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    Novus Biologicals CXCL11 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for CXCL11
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--


    CXCL11 for ontologies           About GeneDecksing



    CXCL11 Antibody Products: 
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    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CXCL11 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR027221 CXCL11
     IPR001811 Chemokine_IL8-like_dom
     IPR001089 Chemokine_CXC
     IPR018048 Chemokine_CXC_CS

    Graphical View of Domain Structure for InterPro Entry O14625

    ProtoNet protein and cluster: O14625

    UniProtKB/Swiss-Prot: CXL11_HUMAN, O14625
    Similarity: Belongs to the intercrine alpha (chemokine CxC) family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CXL11_HUMAN, O14625
    Function: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces
    calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell
    recruitment. May play a role in skin immune responses
    Induction: By IFNG/IFN-gamma and IFNB1/IFN-beta. Induction by IFNG/IFN-gamma is enhanced by TNF in monocytes, dermal
    fibroblasts and endothelial cells, and by IL1/interleukin-1 in astrocytes

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CXCL11 (see all 7)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CXCL11 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXCL11

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008009chemokine activity IEA--


    CXCL11 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CXCL11:
     Increased HPV18 LCR reporter a 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/12 super-pathways (see all 12About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1PEDF Induced Signaling
    8/9 pathways (see all 9)
    PEDF Induced Signaling1.00
    RAR-Gamma-RXR-Alpha Degradation0.54
    MIF Mediated Glucocorticoid Regulation0.73
    STAT3 Pathway0.47
    MIF Regulation of Innate Immune Cells0.71
    Endothelin-1 Signaling Pathway0.44
    IL-6 Pathway0.61
    Cytokine-cytokine receptor interaction0.26
    2Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)1.00
    Peptide ligand-binding receptors0.61
    GPCR ligand binding0.75
    G alpha (i) signalling events0.44
    3Rho Family GTPases
    Rho Family GTPases1.00
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    4Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    GPCR downstream signaling0.89
    5Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response
    Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response1.00
    Immune response_TLR signaling pathways0.94

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for CXCL11
        Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response

    5/17 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CXCL11 (see all 17)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    Transendothelial Migration of Leukocytes
    MIF Mediated Glucocorticoid Regulation

    1 GeneGo (Thomson Reuters) Pathway for CXCL11
        Immune response TLR signaling pathways

    2 BioSystems Pathways for CXCL11 
        Toll-like receptor signaling pathway
    CXCR3-mediated signaling events

    5/8        Reactome Pathways for CXCL11 (see all 8)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Chemokine receptors bind chemokines
    Signal Transduction
    Signaling by GPCR


    3         Kegg Pathways  (Kegg details for CXCL11):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway
    Toll-like receptor signaling pathway


    CXCL11 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CXCL11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/155 Interacting proteins for CXCL11 (O146252, 3 ENSP000003068844) via UniProtKB, MINT, STRING, and/or I2D (see all 155)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DPP4P274872, 3, ENSP000003537314MINT-8091131 I2D: score=2 STRING: ENSP00000353731
    CCR3P516773, ENSP000003500034I2D: score=1 STRING: ENSP00000350003
    CXCR3P496823, ENSP000003627954I2D: score=3 STRING: ENSP00000362795
    AGTR2ENSP000003609734STRING: ENSP00000360973
    C3ENSP000002459074STRING: ENSP00000245907
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis IEA--
    GO:0006954inflammatory response IEA--
    GO:0006955immune response IEA--
    GO:0007165signal transduction TAS10233762
    GO:0007267cell-cell signaling TAS10233762


    CXCL11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CXCL11 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CXCL11

    1 HMDB Compound for CXCL11    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    10/11 Novoseek chemical compound relationships for CXCL11 gene (see all 11)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rantes 73 21 11533168 (2), 11110785 (1), 19397398 (1), 15663962 (1) (see all 17)
    ccl3 63.6 6 12960247 (2), 15178708 (1), 19406226 (1), 19067439 (1) (see all 5)
    tarc 62.2 3 16453150 (2), 11533168 (1)
    ccl4 40.3 6 12960247 (2), 19265171 (1), 19067439 (1), 17912012 (1)
    lysophosphatidylcholine 20.5 2 11795279 (1), 15621055 (1)
    calcium 5.38 15 17363734 (2), 11500837 (2), 15713646 (1), 10825390 (1) (see all 10)
    oligonucleotide 0 1 11533168 (1)
    progesterone 0 2 15557169 (1), 15126579 (1)
    arginine 0 1 16040184 (1)
    dexamethasone 0 3 10092813 (1), 10843686 (1)

    Search CenterWatch for drugs/clinical trials and news about CXCL11 / CXL11 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CXCL11 gene: 
    NM_005409.4  

    Unigene Cluster for CXCL11:

    Chemokine (C-X-C motif) ligand 11
    Hs.632592  [show with all ESTs]
    Unigene Representative Sequence: NM_005409
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306621(uc003hjm.3) ENST00000503860

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    hsa-miR-2052 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-4263 hsa-miR-3129-5p hsa-miR-221 hsa-miR-9 hsa-miR-3915
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    Additional cDNA sequence: 

    AF002985.1 AF030514.1 AF352781.1 BC005292.1 BC012532.1 BC110986.1 BT006787.1 U59286.1 
    U66096.1 Y15220.1 

    1 DOTS entry:

    DT.305593 

    24/26 AceView cDNA sequences (see all 26):

    BX646683 U66096 BI820123 AA594458 D62634 NM_005409 AL703031 AW802652 
    Y15220 BX112006 AA554678 BQ029949 BT006787 AF030514 BC012532 CB986207 
    BC005292 AA372656 BG687080 AF002985 BF209312 AF352781 AA361853 BF910176 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CXCL11    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b
    SP1:                              
    SP2:                              


    ECgene alternative splicing isoforms for CXCL11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CXCL11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTATATACT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CXCL11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CXCL11

    SOURCE GeneReport for Unigene cluster: Hs.632592

    UniProtKB/Swiss-Prot: CXL11_HUMAN, O14625
    Tissue specificity: High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in
    thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer
    keratinocytes in skin disorders

        SABiosciences Expression via Pathway-Focused PCR Arrays including CXCL11 (see all 10): 
              Antiviral Response in human mouse rat
              Angiogenic Growth Factors in human mouse rat
              Multiple Sclerosis in human mouse rat
              Wound Healing in human mouse rat
              Inflammatory Response & Autoimmunity in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CXCL11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CXCL11 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cxcl115 chemokine (C-X-C motif) ligand 11   --   5 (46.61 cM) 92359544 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-202a12.76
    cxc646
    (see all 4)
    CXC chemokine 64
    (see all 4)
    36(a)
    32(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    5(43700834-43701312)
    5(40352744-40354399)


    ENSEMBL Gene Tree for CXCL11 (if available)
    TreeFam Gene Tree for CXCL11 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CXCL11
         1 CNV: 63866
    Human Gene Mutation Database (HGMD): CXCL11
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CXCL11
    DNA2.0 Custom Variant and Variant Library Synthesis for CXCL11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CXCL11 for disorders           About GeneDecksing

    OMIM gene information: 604852    OMIM disorders: --

    20/61 diseases for CXCL11 (see all 61):    About MalaCards
    relapsing-remitting multiple sclerosis    inclusion body myositis    mycosis fungoides    graft versus host disease
    nasal cavity adenocarcinoma    lichen planus    pre-eclampsia    vernal keratoconjunctivitis
    optic neuritis    chronic obstructive pulmonary disease    idiopathic pulmonary fibrosis    multiple sclerosis
    systemic lupus erythematosus    renal cell carcinoma    keratoconjunctivitis    neuritis
    lupus erythematosus    hypothyroidism, autoimmune    pulmonary fibrosis    septic arthritis

    10/17 Novoseek disease relationships for CXCL11 gene (see all 17)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 54.2 12 17363734 (1), 16378910 (1), 19155971 (1), 11208713 (1) (see all 9)
    multiple sclerosis 40 2 15789559 (1), 12162873 (1)
    dermatitis allergic contact 34.2 4 10504443 (2), 10903743 (1), 10233762 (1)
    hepatitis c chronic 29.3 1 15653416 (1)
    dermatitis 28.2 1 11523046 (1)
    necrosis 22.2 9 19095263 (4), 17666446 (1), 20470259 (1), 11208713 (1) (see all 6)
    lichen planus 21.4 1 10233762 (1)
    mycosis fungoides 20.1 1 10233762 (1)
    tumors 19.2 23 16783574 (3), 19095263 (3), 20470259 (1), 11208713 (1) (see all 11)
    rheumatoid arthritis 15.4 1 18793417 (1)

    Human Genome Epidemiology (HuGE) Navigator: CXCL11 (4 documents)

    Export disorders for CXCL11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CXCL11 gene, integrated from 9 sources (see all 233):
    (articles sorted by number of sources associating them with CXCL11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human gene encoding SCYB9B, a putative novel CXC chemokine, maps to human chromosome 4q21 like the closely related genes for MIG (SCYB9) and INP10 (SCYB10). (PubMed id 9730616)1, 2, 3 Erdel M....Werner-Felmayer G. (1998)
    2. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. (PubMed id 9625760)1, 2, 9 Cole K.E....Neote K. (1998)
    3. Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha. (PubMed id 8798467)1, 2, 9 Rani M.R.S....Ransohoff R.M. (1996)
    4. Structure and expression of the human small cytokine B subfamily member 11 (SCYB11/formerly SCYB9B, alias I-TAC) gene cloned from IFN- gamma-treated human monocytes (THP-1). (PubMed id 10386863)1, 2, 9 Laich A.M.... Werner-Felmayer G. (1999)
    5. NMR structure of CXCR3 binding chemokine CXCL11 (ITAC). (PubMed id 15273303)1, 2, 9 Booth V.... Sykes B.D. (2004)
    6. Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation. (PubMed id 18645041)1, 2, 9 Loos T.... Proost P. (2008)
    7. Human IP-9: a keratinocyte derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3). (PubMed id 10233762)1, 2, 9 Tensen C.P.... Willemze R. (1999)
    8. Genomic organization, sequence and transcriptional regulation of the human CXCL 11 gene. (PubMed id 10395932)1, 2, 9 Tensen C.P.... Willemze R. (1999)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. A genetic selection for isolating cDNAs encoding secreted proteins. (PubMed id 9370294)1, 2 Jacobs K.A.... McCoy J.M. (1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6373 HGNC: 10638 AceView: CXCL11 Ensembl:ENSG00000169248 euGenes: HUgn6373
    ECgene: CXCL11 Kegg: 6373 H-InvDB: CXCL11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CXCL11 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/CXCL11

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CXCL11 gene:
    Search GeneIP for patents involving CXCL11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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