Aliases for CXCL10 Gene
External Ids for CXCL10 Gene
Previous HGNC Symbols for CXCL10 Gene
Previous GeneCards Identifiers for CXCL10 Gene
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
GeneCards Summary for CXCL10 Gene
CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Diseases associated with CXCL10 include Endotheliitis and Severe Acute Respiratory Syndrome. Among its related pathways are Peptide ligand-binding receptors and TNF signaling pathway. GO annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL9.
UniProtKB/Swiss-Prot for CXCL10 Gene
Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.