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Aliases for CWF19L2 Gene

Aliases for CWF19L2 Gene

  • CWF19-Like 2, Cell Cycle Control (S. Pombe) 2 3

External Ids for CWF19L2 Gene

Previous GeneCards Identifiers for CWF19L2 Gene

  • GC11M106735
  • GC11M106702
  • GC11M107197
  • GC11M103133

Summaries for CWF19L2 Gene

GeneCards Summary for CWF19L2 Gene

CWF19L2 (CWF19-Like 2, Cell Cycle Control (S. Pombe)) is a Protein Coding gene. An important paralog of this gene is CWF19L1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CWF19L2 Gene

Genomics for CWF19L2 Gene

Regulatory Elements for CWF19L2 Gene

Genomic Location for CWF19L2 Gene

Start:
107,326,345 bp from pter
End:
107,457,846 bp from pter
Size:
131,502 bases
Orientation:
Minus strand

Genomic View for CWF19L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CWF19L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CWF19L2 Gene

Proteins for CWF19L2 Gene

  • Protein details for CWF19L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2TBE0-C19L2_HUMAN
    Recommended name:
    CWF19-like protein 2
    Protein Accession:
    Q2TBE0
    Secondary Accessions:
    • A4FU66
    • A4FU67
    • A4FU68
    • Q6PHW1
    • Q96MI1

    Protein attributes for CWF19L2 Gene

    Size:
    894 amino acids
    Molecular mass:
    103787 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI10440.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI10441.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI10441.1; Type=Frameshift; Positions=754; Evidence={ECO:0000305}; Sequence=AAI10442.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI10443.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI18670.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB71307.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CWF19L2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CWF19L2 Gene

Proteomics data for CWF19L2 Gene at MOPED

Post-translational modifications for CWF19L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CWF19L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CWF19L2 Gene

Domains for CWF19L2 Gene

Protein Domains for CWF19L2 Gene

Suggested Antigen Peptide Sequences for CWF19L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q2TBE0

UniProtKB/Swiss-Prot:

C19L2_HUMAN :
  • Q2TBE0
Family:
  • Belongs to the CWF19 family.
genes like me logo Genes that share domains with CWF19L2: view

No data available for Gene Families for CWF19L2 Gene

Function for CWF19L2 Gene

Gene Ontology (GO) - Molecular Function for CWF19L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
genes like me logo Genes that share ontologies with CWF19L2: view

Phenotypes for CWF19L2 Gene

genes like me logo Genes that share phenotypes with CWF19L2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CWF19L2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CWF19L2 Gene

Localization for CWF19L2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CWF19L2 Gene COMPARTMENTS Subcellular localization image for CWF19L2 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CWF19L2 Gene

Pathways for CWF19L2 Gene

SuperPathways for CWF19L2 Gene

No Data Available

Interacting Proteins for CWF19L2 Gene

Gene Ontology (GO) - Biological Process for CWF19L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with CWF19L2: view

No data available for Pathways by source for CWF19L2 Gene

Transcripts for CWF19L2 Gene

Unigene Clusters for CWF19L2 Gene

CWF19-like 2, cell cycle control (S. pombe):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CWF19L2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CWF19L2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CWF19L2 Gene

No ASD Table

Relevant External Links for CWF19L2 Gene

GeneLoc Exon Structure for
CWF19L2
ECgene alternative splicing isoforms for
CWF19L2

Expression for CWF19L2 Gene

mRNA expression in normal human tissues for CWF19L2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CWF19L2 Gene

SOURCE GeneReport for Unigene cluster for CWF19L2 Gene Hs.212140

genes like me logo Genes that share expressions with CWF19L2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CWF19L2 Gene

Orthologs for CWF19L2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CWF19L2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CWF19L2 35
  • 99.48 (n)
  • 99.1 (a)
CWF19L2 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CWF19L2 35
  • 88.06 (n)
  • 83.56 (a)
CWF19L2 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CWF19L2 35
  • 88.48 (n)
  • 85.91 (a)
CWF19L2 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cwf19l2 35
  • 81.82 (n)
  • 74.83 (a)
Cwf19l2 16
Cwf19l2 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CWF19L2 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CWF19L2 36
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cwf19l2 35
  • 81.3 (n)
  • 75.11 (a)
chicken
(Gallus gallus)
Aves CWF19L2 35
  • 67.43 (n)
  • 61.4 (a)
CWF19L2 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CWF19L2 36
  • 56 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.5514 35
tropical clawed frog
(Silurana tropicalis)
Amphibia cwf19l2 35
  • 63.75 (n)
  • 60.02 (a)
Str.659 35
zebrafish
(Danio rerio)
Actinopterygii cwf19l2 36
  • 46 (a)
OneToOne
LOC100534870 35
  • 61.18 (n)
  • 60.32 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010932 35
  • 46.1 (n)
  • 35.86 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9213 35
  • 46.12 (n)
  • 37.44 (a)
CG9213 36
  • 32 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea B0361.2 35
  • 50.8 (n)
  • 39.84 (a)
B0361.2 36
  • 34 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 14 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4472 36
  • 38 (a)
OneToOne
Species with no ortholog for CWF19L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CWF19L2 Gene

ENSEMBL:
Gene Tree for CWF19L2 (if available)
TreeFam:
Gene Tree for CWF19L2 (if available)

Paralogs for CWF19L2 Gene

Paralogs for CWF19L2 Gene

genes like me logo Genes that share paralogs with CWF19L2: view

Variants for CWF19L2 Gene

Sequence variations from dbSNP and Humsavar for CWF19L2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs472626 -- 107,383,048(+) tacct(C/T)gccct intron-variant
rs473520 -- 107,345,730(-) CAAAC(G/T)CAAAT intron-variant
rs473551 -- 107,339,157(-) gatgc(A/G)tgaaa intron-variant
rs473830 -- 107,360,312(-) gaaat(C/T)gtgtt intron-variant
rs474053 -- 107,438,962(+) ttgag(G/T)gggag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CWF19L2 Gene

Variant ID Type Subtype PubMed ID
nsv898364 CNV Gain 21882294
dgv1312n71 CNV Gain 21882294
nsv898373 CNV Gain 21882294
nsv832261 CNV Loss 17160897
nsv898374 CNV Loss 21882294
nsv475 CNV Loss 18451855
esv2745047 CNV Deletion 23290073
nsv75 CNV Loss 15895083
nsv508655 CNV Loss 20534489
nsv509441 CNV Insertion 20534489
nsv8872 CNV Loss 18304495
esv1000794 CNV Deletion 20482838
esv26501 CNV Gain+Loss 19812545
dgv239e199 CNV Deletion 23128226
esv2665722 CNV Deletion 23128226
esv2421980 CNV Deletion 20811451
dgv240n67 CNV Loss 20364138
nsv433518 CNV Loss 18776910
nsv511483 CNV Gain 21212237
nsv514590 CNV Complex 21397061
esv2519079 CNV Loss 19546169
esv33566 CNV Gain+Loss 17666407
nsv898375 CNV Gain 21882294
nsv898376 CNV Gain 21882294
nsv898377 CNV Loss 21882294
dgv438e1 CNV Complex 17122850

Relevant External Links for CWF19L2 Gene

HapMap Linkage Disequilibrium report
CWF19L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CWF19L2 Gene

Disorders for CWF19L2 Gene

Relevant External Links for CWF19L2

Genetic Association Database (GAD)
CWF19L2
Human Genome Epidemiology (HuGE) Navigator
CWF19L2
genes like me logo Genes that share disorders with CWF19L2: view

No data available for UniProtKB/Swiss-Prot for CWF19L2 Gene

Publications for CWF19L2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients. (PMID: 18398821) Nordgard S.H. … Kristensen V.N. (Genes Chromosomes Cancer 2008) 3 48
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M. … Tokunaga K. (Hum. Genet. 2010) 3 48
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for CWF19L2 Gene

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