CWC27 Gene

Aliases
for CWC27 gene

Previous GC identifer: GC05P061019

Summaries
for CWC27 gene

Genomic Views
for CWC27 gene

RefSeq DNA sequence:

NC_000005.9  NC_018916.1  NT_006713.15  

SwitchGear Promoter luciferase reporter plasmid: CWC27 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CWC27

CWC27 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P064064:  view genomic region     (about GC identifiers)

Proteins
for CWC27 gene

1 PDB 3D structure from and Proteopedia for CWC27:

2HQ6 (3D)    

Explore the universe of human proteins at neXtProt for CWC27: NX_Q6UX04

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: CWC27 OriGene Custom Protein Services for CWC27
	GenScript Custom Purified and Recombinant Proteins Services for CWC27
	Novus Biologicals CWC27 Protein Novus Biologicals CWC27 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CWC27

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	Browse OriGene Antibodies OriGene Custom Antibody Services for CWC27
	GenScript Custom Superior Antibodies Services for CWC27
	Novus Biologicals CWC27 Antibodies
	Search for Antibodies for CWC27 at Abcam
	Uscn Antibodies for CWC27
	Search ThermoFisher Antibodies for CWC27

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CWC27
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CWC27

Protein Domains /
Families
for CWC27 gene

ProtoNet protein and cluster: Q6UX04

Function
for CWC27 gene

Enzyme Number (IUBMB): EC 5.2.1.8¹

miRNA Products:		OriGene 3'-UTR Clone: CWC27 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CWC27
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate CWC27:
		hsa-miR-1323 hsa-miR-3942-5p hsa-miR-377 hsa-miR-205* hsa-miR-548o hsa-miR-548aa
		SwitchGear 3'UTR luciferase reporter plasmid: CWC27 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CWC27 (see all 4) OriGene shRNA RFP: CWC27 OriGene siRNA: CWC27
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CWC27

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for CWC27

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CWC27 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CWC27 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CWC27 (NM_005869)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CWC27
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CWC27

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CWC27
		Search LifeMap BioReagents cell lines for CWC27

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CWC27

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

Pathways & Interactions
for CWC27 gene

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for CWC27 gene

Transcripts
for CWC27 gene

Expression
for CWC27 gene

CWC27 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTTTTTCC

Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Definitive endoderm-like cells (A scalable, suspensi...)
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CWC27 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CWC27
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CWC27
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CWC27

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CWC27

Orthologs
for CWC27 gene

Paralogs
for CWC27 gene

Paralogs for CWC27 gene

PPIL4²  PPWD1²  PPIL3²  PPIH²  PPIB²  PPIC²  PPIL1²  PPIL2²  

15 SIMAP similar genes for CWC27 using alignment to 2 protein entries:     CWC27_HUMAN (see all proteins):

PPIA    PPIL1    PPIL3    PPIF    PPIAL4A    PPIAL4B

PPIAL4C    PPIAL4G    PPIC    NKTR    PPID    PPIH

PPIL2    PPIB    PPIG

CWC27 for paralogs           About GeneDecksing

Genomic Variants
for CWC27 gene

10/3867 NCBI SNPs in CWC27 are shown (see all 3867)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1809620461,2		--	64062829(+)	ATTCTA/GACATA	2	--	us2k1 int1		0	--	--	--	--
rs1379773941,2		--	64062857(+)	AGTCAA/GTATTA	2	--	us2k1 int1		0	--	--	--	--
rs14235321,2	C,F,H,	--	64062958(-)	AAATAT/CGTGAA	2	--	us2k1 int1		11		NS EA NA WA	1560
rs1431057161,2		--	64063116(+)	GCTAAA/GGTCTT	2	--	us2k1 int1		0	--	--	--	--
rs1863753401,2		--	64063484(+)	GTTCAC/TAGTAA	2	--	int1 us2k1		0	--	--	--	--
rs1913255581,2		--	64063551(+)	AAGTGC/TGCTGG	2	--	int1 us2k1		0	--	--	--	--
rs1815341931,2		--	64063644(+)	CTGGTC/TTGAGG	2	--	us2k1 int1		0	--	--	--	--
rs1482517581,2		--	64063649(+)	TTGAGA/GAGATG	2	--	us2k1 int1		0	--	--	--	--
rs168931321,2	C,F,H,	--	64063722(+)	TTATTC/TTGCAG	2	--	int1 us2k1		12		NA NS EA WA CSA	802
rs1418128371,2		--	64063803(+)	TCAACA/GAAGCT	2	--	int1 us2k1		0	--	--	--	--

HapMap Linkage Disequilibrium report for CWC27 (64064755 - 64314590 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for CWC27
     1 CNV: 99161
     4 Indels: 46909 99162 62381 12695

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CWC27

DNA2.0 Custom Variant and Variant Library Synthesis for CWC27

Disorders / Diseases
for CWC27 gene

Publications
for CWC27 gene

PubMed articles for CWC27 gene, integrated from 9 sources (see all 13): (articles sorted by number of sources associating them with CWC27)

Utopia: connect your pdf to the dynamic world of online information

1. Characterization of human colon cancer antigens recognized by autologous antibodies. (PubMed id 9610721)^{1, 2, 3} Scanlan M.J....Old L.J. (1998)
2. The evolutionarily conserved core design of the catal ytic activation step of the yeast spliceosome. (PubMed id 19941820)^{1, 3} Fabrizio P....LA1hrmann R. (2009)
3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
4. A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
5. Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
8. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)² Liu T.... Smith R.D. (2005)
9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
10. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)¹ Jurica M.S.... Moore M.J. (2002)

External Searches for CWC27 gene

Genome Databases showing CWC27 gene

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Products
for CWC27 gene