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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CWC25 Gene

protein-coding   GIFtS: 40
GCID: GC17M036957

CWC25 Spliceosome-Associated Protein Homolog (S. Cerevisiae)

(Previous name: coiled-coil domain containing 49)
(Previous symbol: CCDC49)
  Search for CWC25
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CWC25 Spliceosome-Associated Protein Homolog (S. Cerevisiae)1 2
CCDC491 2 3
Coiled-Coil Domain-Containing Protein 492 3
Coiled-Coil Domain Containing 491
Pre-MRNA-Splicing Factor CWC25 Homolog2
Spliceosome-Associated Protein Homolog CWC253

External Ids:    HGNC: 259891   Entrez Gene: 548832   Ensembl: ENSG000001082967   UniProtKB: Q9NXE83   

Export aliases for CWC25 gene to outside databases

Previous GC identifer: GC17M032753


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CWC25 Gene:
This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing.
Alternatively spliced transcripts have been described for this gene. (provided by RefSeq, Nov 2012)

GeneCards Summary for CWC25 Gene: 
CWC25 (CWC25 spliceosome-associated protein homolog (S. cerevisiae)) is a protein-coding gene.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CWC25
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCWC25 promoter sequence
   Search SABiosciences Chromatin IP Primers for CWC25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CWC25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

CWC25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CWC25 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M036957:  view genomic region     (about GC identifiers)

Start:
36,957,340 bp from pter      End:
36,981,734 bp from pter
Size:
24,395 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CWC25_HUMAN, Q9NXE8 (See protein sequence)
Recommended Name: Pre-mRNA-splicing factor CWC25 homolog  
Size: 425 amino acids; 49647 Da
Secondary accessions: A0JLM3 Q68DK5
Alternative splicing: 2 isoforms:  Q9NXE8-1   Q9NXE8-2   

Explore the universe of human proteins at neXtProt for CWC25: NX_Q9NXE8

Explore proteomics data for CWC25 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NXE8

  • CWC25 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CWC25 Protein Expression
    REFSEQ proteins: NP_060218.1  
    ENSEMBL proteins: 
     ENSP00000225428   ENSP00000464110   ENSP00000466979   ENSP00000465072   ENSP00000464431  
     ENSP00000463646   ENSP00000438566  

    Human Recombinant Protein Products for CWC25: 
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    Novus Biologicals CWC25 Protein
    Novus Biologicals CWC25 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
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    Browse Proteins at Cloud-Clone Corp. 


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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR019339 CIR_N_dom
     IPR022209 CWC25

    Graphical View of Domain Structure for InterPro Entry Q9NXE8

    ProtoNet protein and cluster: Q9NXE8

    UniProtKB/Swiss-Prot: CWC25_HUMAN, Q9NXE8
    Similarity: Belongs to the CWC25 family


    CWC25 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CWC25 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CWC25

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CWC25 
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    miRNA
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    hsa-miR-142-5p hsa-miR-4291 hsa-miR-4311 hsa-miR-875-3p hsa-miR-876-3p hsa-miR-340 hsa-miR-583 hsa-miR-1276
    SwitchGear 3'UTR luciferase reporter plasmidCWC25 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CWC25


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CWC25

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/12 Interacting proteins for CWC25 (Q9NXE82, 3 ENSP000002254284) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-66772 I2D: score=5 STRING: ENSP00000311695
    RPL27AP467763, ENSP000003460154I2D: score=4 STRING: ENSP00000346015
    ELOVL6Q9H5J43I2D: score=4 
    GTPBP4Q9BZE43I2D: score=4 
    LRPAP1P305333I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CWC25

    Search CenterWatch for drugs/clinical trials and news about CWC25

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CWC25 gene: 
    NM_017748.4  

    Unigene Cluster for CWC25:

    CWC25 spliceosome-associated protein homolog (S. cerevisiae)
    Hs.406223  [show with all ESTs]
    Unigene Representative Sequence: NR_073428
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225428(uc002hqu.3 uc010wdv.2) ENST00000585298 ENST00000578906(uc010wdw.1)
    ENST00000584007 ENST00000581092 ENST00000582713(uc010wdx.1) ENST00000583435
    ENST00000536127
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CWC25
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CWC25 (see all 13):
    hsa-miR-142-5p hsa-miR-4291 hsa-miR-4311 hsa-miR-875-3p hsa-miR-876-3p hsa-miR-340 hsa-miR-583 hsa-miR-1276
    SwitchGear 3'UTR luciferase reporter plasmidCWC25 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for CWC25
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    Clone
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    OriGene clones in human, mouse for CWC25 (see all 7)
    OriGene ORF clones in mouse, rat for CWC25
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    GenScript: all cDNA clones in your preferred vector: CWC25 (NM_017748)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CWC25
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CWC25
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CWC25

    Additional mRNA sequence: 

    AK000298.1 AK225373.1 AK296115.1 AK302983.1 AK316077.1 BC003085.1 BC008833.2 CR749362.1 
    NR_073428.1 

    9 DOTS entries:

    DT.412954  DT.120918033  DT.75125453  DT.95269752  DT.100785533  DT.120918020  DT.95269753  DT.120917950 
    DT.65286329 

    24/148 AceView cDNA sequences (see all 148):

    AA928647 CB140934 BM672132 C01349 AI239971 AW473745 BP348701 BC003085 
    AL543506 BM919997 AI452549 BM974688 BF435431 AI564637 AI434661 BM504000 
    AA933683 AI524355 AA969252 AI201047 BC008833 NM_017748 AW182365 BG236139 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CWC25 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13
    SP1:                          -                                   -     -     -                       -                           
    SP2:                                                                                                                              
    SP3:                                                              -           -                       -                           
    SP4:                          -           -     -     -     -     -     -     -     -     -           -                           
    SP5:                                                                          -                       -                           


    ECgene alternative splicing isoforms for CWC25

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CWC25 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CWC25 Expression
    About this image


    See CWC25 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CWC25

    SOURCE GeneReport for Unigene cluster: Hs.406223
        SABiosciences Custom PCR Arrays for CWC25
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CWC25

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CWC25 gene from 10/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cwc251 , 5 CWC25 spliceosome-associated protein homolog (S. cerevisiae) less1, 5 86.62(n)1
    90.62(a)1
      11 (61.09 cM)5
    674801  NM_026186.41  NP_080462.21 
     977454815 
    chicken
    (Gallus gallus)
    Aves CWC251 CWC25 spliceosome-associated protein homolog (S. cerevisiae) less 73.69(n)
    77(a)
      420000  XM_418121.3  XP_418121.1 
    lizard
    (Anolis carolinensis)
    Reptilia CWC256
    Uncharacterized protein
    70(a)
    1 ↔ 1
    6(63147557-63157529)
    African clawed frog
    (Xenopus laevis)
    Amphibia AF549897-prov2 conserved hypothetical protein 79.4(n)    AF549897.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.55342 Danio rerio mRNA similar to RIKEN cDNA 1300013D05 gene (cDNA clone MGC55552 IMAGE2642768), complete cds less 74.39(n)    BC045380.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cwc251 CG2843-PA 46.19(n)
    38.03(a)
      33460  NM_134861.1  NP_608705.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F52C9.71 Protein F52C9.7 42.73(n)
    32.89(a)
      175730  NM_065733.3  NP_498134.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CWC256
    Splicing factor required for the first step of pre...
    26(a)
    1 ↔ 1
    XIV(186346-186885)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G442001 pre-mRNA splicing factor domain-containing protein 43.13(n)
    33.76(a)
      819028  NM_129984.2  NP_566014.1 
    rice
    (Oryza sativa)
    Liliopsida Os08g05002001 hypothetical protein 44.53(n)
    33.6(a)
      4345946  NM_001068689.1  NP_001062154.1 


    ENSEMBL Gene Tree for CWC25 (if available)
    TreeFam Gene Tree for CWC25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/516 SNPs in CWC25 are shown (see all 516)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs581313681,2
    C--32778074(+) TATTT-/ATTT/ 
    ATTTATTT
    CGAGA
    2 -- us2k11NA 2
    rs1889356661,2
    --32778915(+) AGATAC/GCGCCA 2 -- us2k10--------
    rs1925349661,2
    --36958222(+) CAGGGC/TCACTT 2 -- ut31 nc-transcript-variant0--------
    rs1836477891,2
    --36958279(+) TATAAA/GGAGAA 2 -- ut31 nc-transcript-variant0--------
    rs1882565871,2
    C--36958326(+) AACCAA/GTAAGA 2 -- ut31 nc-transcript-variant0--------
    rs2008279411,2
    C--36958425(+) CTCCAG/TGGAGG 3 M L mis11Minor allele frequency- T:0.00EU 593
    rs2010528041,2
    --36958455(+) CTTCAC/TGCGGC 3 M V mis10--------
    rs1460964351,2
    C--36958571(+) ACACAA/GCCTCT 2 -- int10--------
    rs1810810321,2
    --36958696(+) AAAAAA/GGCTTC 2 -- int10--------
    rs2002303211,2
    --36958719(+) TCTTA-/CTTAAA 2 -- int10--------

    HapMap Linkage Disequilibrium report for CWC25 (36957340 - 36981734 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for CWC25:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2715898CNV Deletion23290073
    esv1005760CNV Deletion20482838
    esv2668927CNV Deletion23128226
    nsv908199CNV Loss21882294
    nsv512485CNV Loss21212237
    nsv833439CNV Loss17160897
    nsv827983CNV Loss20364138
    nsv833438CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CWC25
    DNA2.0 Custom Variant and Variant Library Synthesis for CWC25

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CWC25 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with CWC25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The evolutionarily conserved core design of the catal ytic activation step of the yeast spliceosome. (PubMed id 19941820)1, 3 Fabrizio P....LA1hrmann R. (2009)
    2. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    4. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    5. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    6. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54883 HGNC: 25989 AceView: FLJ20291 Ensembl:ENSG00000108296 euGenes: HUgn54883
    ECgene: CWC25 H-InvDB: CWC25

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CWC25 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CWC25 gene:
    Search GeneIP for patents involving CWC25

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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