Aliases for CUX2 Gene
External Ids for CUX2 Gene
Previous HGNC Symbols for CUX2 Gene
Previous GeneCards Identifiers for CUX2 Gene
This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. [provided by RefSeq, Jan 2013]
GeneCards Summary for CUX2 Gene
CUX2 (Cut Like Homeobox 2) is a Protein Coding gene. Diseases associated with CUX2 include Fiedler's Myocarditis and Heterotopia, Periventricular. GO annotations related to this gene include sequence-specific DNA binding and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is CUX1.
UniProtKB/Swiss-Prot for CUX2 Gene
May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner (By similarity).