CUL5 Gene
protein-coding GIFtS: 64
GCID: GC11P107913
|
|
cullin 5
| |
Aliases
for CUL5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cullin 51 2 | | CUL-52 3 | | VACM-11 2 3 | | Cullin-51 | | VACM12 3 5 | | Cullin-5 (Vasopressin-Activated Calcium-Mobilizing Receptor-1)2 | | Vasopressin-Activated Calcium-Mobilizing Receptor 12 3 | | Vasopressin-Activated Calcium-Mobilizing Receptor-12 |
Export aliases for CUL5 gene to outside databasesPrevious GC identifers: GC11P110074 GC11P109236 GC11P107417 GC11P107384 GC11P103804 |
Summaries
for CUL5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CUL5_HUMAN, Q93034Function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligasecomplexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffoldprotein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Thefunctional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognitioncomponent. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor
Gene Wiki entry for CUL5
|
Genomic Views
for CUL5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CUL5 gene promoter:
ER-alpha AhR C/EBPalpha Arnt YY1 CHOP-10 N-Myc Zic1 ARP-1 ZID
Other transcription factors
Search SABiosciences Chromatin IP Primers for CUL5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CUL5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q22.3 Ensembl cytogenetic band: 11q22.3 HGNC cytogenetic band: 11q22.3CUL5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P107913: view genomic region
(about GC identifiers)
Start:
|
107,879,408 bp from pter |
End:
|
107,978,503 bp from pter |
Size:
|
99,096 bases |
Orientation:
|
plus strand |
|
Proteins
for CUL5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CUL5_HUMAN, Q93034 (See
protein sequence)Recommended Name: Cullin-5 Size: 780 amino acids; 90955 Da
Subunit: Component of multiple ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes formed ofCUL5, Elongin BC (TCEB1 and TCEB2), RBX2 and a variable SOCS box domain-containing protein as substrate-specificrecognition component. Component of the probable ECS(LRRC41) complex with the substrate recognition component LRRC41.Component of the probable ECS(SOCS1) complex with the substrate recognition component SOCS1. Component of the probableECS(WSB1) complex with the substrate recognition subunit WSB1. Component of the probable ECS(SOCS3) complex with thesubstrate recognition component SOCS3. Component of the probable ECS(SPSB1) complex with the substrate recognitioncomponent SPSB1. Component of the probable ECS(SPSB2) complex with the substrate recognition component SPSB2.Component of the probable ECS(SPSB4) complex with the substrate recognition component SPSB4. Component of the probableECS(RAB40C) complex with the substrate recognition subunit RAB40C. May also form complexes containing CUL5, elongin BCcomplex (TCEB1 and TCEB2), RBX1 and TCEB3. May also form complexes containing CUL5, Elongin BC (TCEB1 and TCEB2), RBX1and VHL. The substrate recognition component can also be a viral protein such as HIV Vif, or human adenovirus 5 E1Blarge T-antigen and E4-orf6. Interacts with RNF7/RBX2, LRRC41, SOCS3, SPSB1, SPSB2, SPSB4 and RAB40C. Interacts withASB1, ASB2, ASB6, ASB7 and ASB12
2 PDB 3D structures from  and Proteopedia  for CUL5:3DPL (3D)
3DQV (3D)
Secondary accessions: A8K960 O14766 Q9BZC6Explore the universe of human proteins at neXtProt for CUL5: NX_Q93034
Post-translational modifications:
Neddylated. Deneddylated via its interaction with the COP9 signalosome (CSN) complex (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q93034
CUL5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003469.2
ENSEMBL proteins: ENSP00000376808 ENSP00000436494 ENSP00000435376 ENSP00000431221 Reactome Protein details: Q93034
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
CUL5 for ontologies About GeneDecksing
CUL5 Antibody Products:
Assay Products for CUL5: |
Protein
Domains /
Families
for CUL5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CUL5 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q93034ProtoNet protein and cluster: Q93034 1 Blocks protein family: IPB001373 Cullin
UniProtKB/Swiss-Prot: CUL5_HUMAN, Q93034Similarity: Belongs to the cullin family |
Function
for CUL5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CUL5_HUMAN, Q93034Function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligasecomplexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffoldprotein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Thefunctional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognitioncomponent. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor Genatlas biochemistry entry for CUL5:cullin 5,widely expressed,C elegans,cullin Cdc53 (CUL) family member,negative regulator of cell cycle
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CUL5 (NM_003478) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CUL5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CUL5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CUL5 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CUL5 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CUL5:
|
Pathways & Interactions
for CUL5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | | | 3 | HIV Infection | | | 4 | Ubiquitinated Orc1 is degraded by the proteasome | | | 5 | Disease | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CUL5
5/12 
Reactome Pathways for CUL5 (see all 12)
1 
Kegg Pathway (Kegg details for CUL5):
UniProtKB/Swiss-Prot: CUL5_HUMAN, Q93034Pathway: Protein modification; protein ubiquitination
CUL5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CUL5
5/133 Interacting proteins for CUL5 (Q930341, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 133)
About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
CUL5 for ontologies About GeneDecksing
|
Drugs & Compounds
for CUL5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CUL5 for compounds About GeneDecksing
 Browse Tocris compounds for CUL5
1 HMDB Compound for CUL5 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Vasopressin | 3-(Phenylalanine)-8-lysine oxytocin (see all 8) | 11000-17-2 | -- |
2 Novoseek chemical compound relationships for CUL5 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| acetylene |
49.2 |
3 |
16636053 (3) |
| calcium |
0 |
4 |
17186378 (1), 15762197 (1) |
Search CenterWatch for drugs/clinical trials and news about CUL5
|
Transcripts
for CUL5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CUL5 gene: NM_003478.3 Unigene Cluster for CUL5: Cullin 5 Hs.744123 [show with all ESTs]Unigene Representative Sequence: NM_0034786 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393094(uc001pju.3 uc001pjv.3) ENST00000532064 ENST00000526303
ENST00000531427 ENST00000532782 ENST00000531843
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CUL5 (NM_003478) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CUL5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CUL5 |
Additional cDNA sequence: AF017061.1 AF327710.1 AK125294.1 AK292575.1 BC017838.1 BC037203.1 BC063306.1 X81882.1 10 DOTS entries: DT.441965 DT.442301 DT.97789810 DT.100748383 DT.120707136 DT.120707137 DT.120707182 DT.97823023 DT.100680560 DT.40131194 24/165 AceView cDNA sequences (see all 165): AL599947 AW303561 AA788673 AI619822 AW268641 AI478539 AA151127 AA765994 AI292184 BX499523 AA972127 BX097158 CA391812 AA804245 AA256943 AI376842 AK125294 CB053708 AA403250 BU784350 AI674090 AI688961 BE674758 BM472371
GeneLoc Exon Structure
|
Expression
for CUL5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CUL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAGCTTTCC
About this image
See CUL5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CUL5
SOURCE GeneReport for Unigene cluster: Hs.744123
SABiosciences Expression via Pathway-Focused PCR Arrays including CUL5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CUL5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CUL5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CUL5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CUL5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CUL5 |
Orthologs
for CUL5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CUL5 gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CUL51 |
cullin 5 |
87.37(n)
99.48(a) |
|
418969 XM_417163.3 XP_417163.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CUL56 |
-- |
99(a) |
1 ↔ 1 |
GL343659.1(210936-237686) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.145002 |
Xenopus laevis transcribed sequence with strong similarity more |
80.17(n) |
|
BJ042671.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufi20h122 |
Danio rerio Vasopressin-activated calcium-mobilizing more |
78.76(n) |
|
BC057475.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG14013
Cul-51 |
vasopressin activated calcium mobilizing
receptor3
Cullin-51 |
67(a)3
59.58(n)1
67.19(a)1 |
|
98F63
434341 NM_143408.21 NP_651665.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
cul-51 , 3 |
Cullin family3
Protein CUL-51 |
49(a)3
56.2(n)1
52.98(a)1 |
|
V(10182152-10185480)3
1794131 NM_073215.31 NP_505616.21 |
ENSEMBL Gene Tree for CUL5 (if available)
TreeFam Gene Tree for CUL5 (if available) |
Paralogs
for CUL5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CUL5 gene
- CUL12 CUL32 CUL22 CUL4B2 CUL4A2
2 SIMAP similar genes for CUL5 using alignment to 5 protein entries: CUL5_HUMAN (see all proteins):CUL1 CUL2
CUL5 for paralogs About GeneDecksing
|
Genomic Variants
for CUL5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CUL5 (107879408 - 107978503 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CUL5
1 CNV: 8697
Human Gene Mutation Database (HGMD): CUL5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CUL5 |
|
Disorders
/ Diseases
for CUL5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CUL5 for disorders About GeneDecksing
OMIM gene information: 601741
OMIM disorders: --
11  diseases for CUL5: About MalaCardsataxia telangiectasia rabies lung adenocarcinoma ataxia
adenocarcinoma breast cancer immunodeficiency thyroiditis
malaria leukemia neuronitis
1 Novoseek disease relationship for CUL5 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
5 |
12878869 (1), 19147357 (1) |
Human Genome Epidemiology (HuGE) Navigator: CUL5 (1 document)
Export disorders for CUL5 gene to outside databases
|
Publications
for CUL5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CUL5 gene, integrated from 9 sources (see all 131):
(articles sorted by number of sources associating them with CUL5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23. (PubMed id 9037604)1, 2, 3, 9 Byrd P.J....Taylor A.M.R. (1997)
- Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. (PubMed id 12186903)1, 2, 9 Harada J.N.... Berk A.J. (2002)
- Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation. (PubMed id 15574592)1, 2, 9 Mehle A.... Gabuzda D. (2004)
- ASB proteins interact with cullin5 and Rbx2 to form E3 ubiquitin ligase complexes. (PubMed id 16325183)1, 2 Kohroki J.... Masuho Y. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Muf1, a novel elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. (PubMed id 11384984)1, 2 Kamura T.... Conaway J.W. (2001)
- ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. (PubMed id 10230407)1, 2 Ohta T.... Xiong Y. (1999)
- Covalent modification of all members of human cullin family proteins by NEDD8. (PubMed id 10597293)1, 2 Hori T.... Tanaka K. (1999)
- cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. (PubMed id 8681378)1, 3 Kipreos E.T.... Hedgecock E.M. (1996)
|
External Searches for CUL5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CUL5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CUL5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CUL5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CUL5 gene:
Search GeneIP for patents involving CUL5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CUL5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for CUL5 | | OriGene shRNA RFP for CUL5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CUL5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CUL5 | | | OriGene Protein Over-expression Lysate for CUL5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CUL5 | | OriGene 3'-UTR Clone for CUL5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CUL5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CUL5 | | OriGene Custom Protein Services for CUL5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CUL5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CUL5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CUL5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CUL5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CUL5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CUL5 |
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| | | | Search Tocris compounds for CUL5 |
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 | | | CUL5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CUL5 |
|  |  |  | | | | ThermoFisher Antibodies for CUL5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CUL5 |
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