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CUEDC1 Gene

protein-coding   GIFtS: 50
GCID: GC17M055940

CUE Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CUE Domain Containing 11 2
CUE Domain-Containing Protein 12

External Ids:    HGNC: 313501   Entrez Gene: 4040932   Ensembl: ENSG000001808917   UniProtKB: Q9NWM33   

Export aliases for CUEDC1 gene to outside databases

Previous GC identifers: GC17M056415 GC17M053295 GC17M051300


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CUEDC1 Gene:
CUEDC1 (CUE domain containing 1) is a protein-coding gene. Diseases associated with CUEDC1 include multiple sclerosis, and tonsillitis.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CUEDC1 gene promoter:
         AML1a   GATA-3   Tal-1   Lmo2   E47   HEN1   c-Rel   Sox9   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CUEDC1 promoter sequence
   Search Chromatin IP Primers for CUEDC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CUEDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.2   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q23.2

CUEDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CUEDC1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M055940:  view genomic region     (about GC identifiers)

Start:
55,938,604 bp from pter      End:
56,032,684 bp from pter
Size:
94,081 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CUED1_HUMAN, Q9NWM3 (See protein sequence)
Recommended Name: CUE domain-containing protein 1  
Size: 386 amino acids; 42258 Da
1 PDB 3D structure from and Proteopedia for CUEDC1:
2DHY (3D)    
Secondary accessions: D3DTZ2 Q9NWD0
Alternative splicing: 2 isoforms:  Q9NWM3-1   Q9NWM3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CUEDC1: NX_Q9NWM3

Explore proteomics data for CUEDC1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys228, Lys318, Lys342
  • Modification sites at PhosphoSitePlus

  • See CUEDC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001258804.1  
    ENSEMBL proteins: 
     ENSP00000462717   ENSP00000384712   ENSP00000462045   ENSP00000462177   ENSP00000353373  
     ENSP00000463666   ENSP00000462789  

    CUEDC1 Human Recombinant Protein Products:

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    Novus Biologicals CUEDC1 Proteins
    Novus Biologicals CUEDC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CUEDC1

    CUEDC1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals CUEDC1 Antibodies
    Search for Antibodies for CUEDC1 at Abcam
    Cloud-Clone Corp. Antibodies for CUEDC1
    Search ThermoFisher Antibodies for CUEDC1
    LSBio Antibodies in human, mouse, rat for CUEDC1

    CUEDC1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for CUEDC1
    Cloud-Clone Corp. CLIAs for CUEDC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR003892 CUE
     IPR009060 UBA-like

    Graphical View of Domain Structure for InterPro Entry Q9NWM3

    ProtoNet protein and cluster: Q9NWM3

    1 Blocks protein domain: IPB003892 Ubiquitin system component Cue

    UniProtKB/Swiss-Prot: CUED1_HUMAN, Q9NWM3
    Similarity: Contains 1 CUE domain


    CUEDC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CUEDC1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CUEDC1:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CUEDC1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CUEDC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CUEDC1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CUEDC1

    miRNA
    Products:
        
    miRTarBase miRNAs that target CUEDC1:
    hsa-mir-9-5p (MIRT021437), hsa-mir-335-5p (MIRT018044)

    Block miRNA regulation of human, mouse, rat CUEDC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CUEDC1 (see all 18):
    hsa-miR-4318 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-449a hsa-miR-378b hsa-miR-1184 hsa-miR-378
    SwitchGear 3'UTR luciferase reporter plasmidCUEDC1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CUEDC1
    Predesigned siRNA for gene silencing in human, mouse, rat CUEDC1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CUEDC1

    Clone
    Products:
         
    OriGene clones in human, mouse for CUEDC1 (see all 7)
    OriGene ORF clones in mouse, rat for CUEDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CUEDC1 (NM_017949)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CUEDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CUEDC1

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CUEDC1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CUEDC1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CUEDC1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    cytoskeleton1
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CUEDC1
    Interactions:

        Search GeneGlobe Interaction Network for CUEDC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for CUEDC1 (Q9NWM32, 3 ENSP000003533734) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF2Q9HAU42, 3, ENSP000002624354MINT-61792 I2D: score=3 STRING: ENSP00000262435
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    KBTBD7Q8WVZ93I2D: score=1 
    TOM1ENSP000004136974STRING: ENSP00000413697
    TOM1L2ENSP000003688184STRING: ENSP00000368818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CUEDC1 (CUED1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CUEDC1 gene: 
    NM_001271875.1  

    Unigene Cluster for CUEDC1:

    CUE domain containing 1
    Hs.46679  [show with all ESTs]
    Unigene Representative Sequence: NR_073495
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000577830(uc002ive.1) ENST00000584746 ENST00000407144 ENST00000577422
    ENST00000582951 ENST00000581391 ENST00000577497 ENST00000578357 ENST00000581898
    ENST00000585294 ENST00000360238(uc002ivd.1) ENST00000577840 ENST00000577589

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CUEDC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CUEDC1 (see all 18):
    hsa-miR-4318 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-449a hsa-miR-378b hsa-miR-1184 hsa-miR-378
    SwitchGear 3'UTR luciferase reporter plasmidCUEDC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CUEDC1
    Predesigned siRNA for gene silencing in human, mouse, rat CUEDC1
    Clone
    Products:
         
    OriGene clones in human, mouse for CUEDC1 (see all 7)
    OriGene ORF clones in mouse, rat for CUEDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CUEDC1 (NM_017949)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CUEDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CUEDC1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CUEDC1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CUEDC1
      QuantiTect SYBR Green Assays in human, mouse, rat CUEDC1
      QuantiFast Probe-based Assays in human, mouse, rat CUEDC1

    Additional mRNA sequence: 

    AK000746.1 AK000977.1 BC056882.1 NR_073495.1 

    17 DOTS entries:

    DT.100091  DT.91939610  DT.100817511  DT.411821  DT.100817512  DT.95272725  DT.91717862  DT.100817513 
    DT.95272723  DT.97820894  DT.120901230  DT.97776374  DT.100029697  DT.100711604  DT.100817515  DT.91717858 
    DT.40228699 

    Selected AceView cDNA sequences (see all 180):

    BU686119 CB241425 BU509455 AI871822 BQ019864 BM709335 BM671784 BM994938 
    BU631252 BU732837 BM726395 AA293162 BX092396 BQ934581 CA428549 BQ960630 
    BC056882 AI281783 AA707921 BE870865 BU685215 AI524442 CR627470 BQ689077 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CUEDC1 (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b · 14c
    SP1:                                                                                                  -           -           -           -               
    SP2:                                                                                -                 -           -           -           -               
    SP3:        -     -     -     -     -     -     -     -                                               -                                                   
    SP4:                                      -     -                                                                                                         
    SP5:                                                                                                              -           -           -               


    ECgene alternative splicing isoforms for CUEDC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CUEDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGACTTAGAA
    CUEDC1 Expression
    About this image


    CUEDC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Eye (Sensory Organs)
             Retina
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    CUEDC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CUEDC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.46679
        Custom PCR Arrays for CUEDC1
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat CUEDC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CUEDC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CUEDC1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cuedc11 , 5 CUE domain containing 11, 5 85.35(n)1
    88.45(a)1
      11 (52.40 cM)5
    1038411  NM_198013.31  NP_932130.21 
     880980585 
    chicken
    (Gallus gallus)
    Aves CUEDC11 CUE domain containing 1 77.01(n)
    81.79(a)
      417665  XM_003642434.2  XP_003642482.2 
    lizard
    (Anolis carolinensis)
    Reptilia CUEDC16
    CUE domain containing 1
    84(a)
    1 ↔ 1
    GL344733.1(110-13166)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cuedc11 CUE domain containing 1 67.25(n)
    72.59(a)
      548971  NM_001016217.2  NP_001016217.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cuedc1b1 CUE domain containing 1b 68.13(n)
    71.93(a)
      556847  NM_001089373.1  NP_001082842.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120241 CG12024 54.7(n)
    42.31(a)
      38243  NM_139413.4  NP_647670.3 


    ENSEMBL Gene Tree for CUEDC1 (if available)
    TreeFam Gene Tree for CUEDC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CUEDC1 gene
    1 SIMAP similar gene for CUEDC1 using alignment to 6 protein entries:     CUED1_HUMAN (see all proteins):
    DKFZp547L163

    CUEDC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CUEDC1 (see all 1911)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1472257101,2
    C,Funtested155951072(+) AGCGCG/ATCGAT 3 /D syn11Minor allele frequency- A:0.00NA 4552
    rs1858499831,2
    C--55938169(+) GGTGTA/GCCACT 2 -- int10--------
    rs3737236821,2
    C--55938187(+) CCCCCC/GGGGTC 2 -- int10--------
    rs1910516581,2
    --55938208(+) GTGGGC/GCCAGA 2 -- int10--------
    rs1467259511,2
    --55938264(+) TGTTGC/TCAGGG 2 -- int10--------
    rs570535581,2
    C,F--55938286(+) TGAGGT/CCACTG 2 -- int14Minor allele frequency- C:0.21WA CSA 124
    rs1405693001,2
    --55938413(+) ACTTCA/GACCTT 2 -- int10--------
    rs1500161561,2
    --55938743(+) CAGCGA/CTAGAC 2 -- ut31 nc-transcript-variant0--------
    rs1451775731,2
    --55938884(+) CTGGGA/GACAAA 2 -- ut31 nc-transcript-variant0--------
    rs1491480341,2
    --55938888(+) GGACAA/TACCCT 2 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for CUEDC1 (55938604 - 56032684 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CUEDC1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv828066CNV Loss20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CUEDC1
    DNA2.0 Custom Variant and Variant Library Synthesis for CUEDC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    7 diseases for CUEDC1:    
    About MalaCards
    multiple sclerosis    tonsillitis    retinitis    thyroiditis
    cerebritis    endotheliitis    prostatitis


    CUEDC1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CUEDC1

    Export disorders for CUEDC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CUEDC1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with CUEDC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. (PubMed id 20802204)1, 4 Baranzini S.E....Pelletier D. (Brain 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Expanding the substantial interactome of NEMO using protein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (PLoS ONE 2010)
    8. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
    9. Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 404093 HGNC: 31350 AceView: CUEDC1 Ensembl:ENSG00000180891 euGenes: HUgn404093
    ECgene: CUEDC1 H-InvDB: CUEDC1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CUEDC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CUEDC1 gene:
    Search GeneIP for patents involving CUEDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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