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Aliases for CTXN2 Gene

Aliases for CTXN2 Gene

  • Cortexin 2 2 3
  • Cortexin-2 3

External Ids for CTXN2 Gene

Previous GeneCards Identifiers for CTXN2 Gene

  • GC15U900443
  • GC15P048483
  • GC15P025316

Summaries for CTXN2 Gene

GeneCards Summary for CTXN2 Gene

CTXN2 (Cortexin 2) is a Protein Coding gene. An important paralog of this gene is CTXN1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTXN2 Gene

Genomics for CTXN2 Gene

Regulatory Elements for CTXN2 Gene

Genomic Location for CTXN2 Gene

Start:
48,178,349 bp from pter
End:
48,203,756 bp from pter
Size:
25,408 bases
Orientation:
Plus strand

Genomic View for CTXN2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CTXN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTXN2 Gene

Proteins for CTXN2 Gene

  • Protein details for CTXN2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C2S0-CTXN2_HUMAN
    Recommended name:
    Cortexin-2
    Protein Accession:
    P0C2S0
    Secondary Accessions:

    Protein attributes for CTXN2 Gene

    Size:
    81 amino acids
    Molecular mass:
    8980 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CTXN2 Gene

Proteomics data for CTXN2 Gene at MOPED

Post-translational modifications for CTXN2 Gene

No Post-translational modifications

Other Protein References for CTXN2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTXN2 Gene

Domains for CTXN2 Gene

Protein Domains for CTXN2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CTXN2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C2S0

UniProtKB/Swiss-Prot:

CTXN2_HUMAN :
  • P0C2S0
Family:
  • Belongs to the cortexin family.
genes like me logo Genes that share domains with CTXN2: view

No data available for Gene Families for CTXN2 Gene

Function for CTXN2 Gene

Phenotypes for CTXN2 Gene

GenomeRNAi human phenotypes for CTXN2:
genes like me logo Genes that share phenotypes with CTXN2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CTXN2 Gene

Localization for CTXN2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTXN2 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CTXN2 Gene COMPARTMENTS Subcellular localization image for CTXN2 gene
Compartment Confidence
cytosol 2
extracellular 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CTXN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0031224 intrinsic component of membrane --
genes like me logo Genes that share ontologies with CTXN2: view

Pathways for CTXN2 Gene

SuperPathways for CTXN2 Gene

No Data Available

Interacting Proteins for CTXN2 Gene

Gene Ontology (GO) - Biological Process for CTXN2 Gene

None

No data available for Pathways by source for CTXN2 Gene

Transcripts for CTXN2 Gene

mRNA/cDNA for CTXN2 Gene

(5) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTXN2 Gene

Cortexin 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CTXN2 Gene

No ASD Table

Relevant External Links for CTXN2 Gene

GeneLoc Exon Structure for
CTXN2
ECgene alternative splicing isoforms for
CTXN2

Expression for CTXN2 Gene

mRNA expression in normal human tissues for CTXN2 Gene

mRNA differential expression in normal tissues according to GTEx for CTXN2 Gene

This gene is overexpressed in Brain - Hypothalamus (6.1), Brain - Frontal Cortex (BA9) (5.6), Brain - Cortex (5.3), and Brain - Anterior cingulate cortex (BA24) (4.7).

SOURCE GeneReport for Unigene cluster for CTXN2 Gene Hs.721408

genes like me logo Genes that share expressions with CTXN2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for CTXN2 Gene

Orthologs for CTXN2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CTXN2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CTXN2 35
  • 100 (n)
  • 100 (a)
CTXN2 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CTXN2 35
  • 96.3 (n)
  • 98.77 (a)
CTXN2 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CTXN2 35
  • 96.71 (n)
  • 100 (a)
CTXN2 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ctxn2 35
  • 86.83 (n)
  • 95.06 (a)
Ctxn2 16
Ctxn2 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CTXN2 36
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CTXN2 36
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ctxn2 35
  • 83.54 (n)
  • 95.06 (a)
chicken
(Gallus gallus)
Aves LOC100859495 35
  • 83.95 (n)
  • 90.12 (a)
zebrafish
(Danio rerio)
Actinopterygii ctxn2 35
  • 65 (n)
  • 65 (a)
Species with no ortholog for CTXN2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CTXN2 Gene

ENSEMBL:
Gene Tree for CTXN2 (if available)
TreeFam:
Gene Tree for CTXN2 (if available)

Paralogs for CTXN2 Gene

Paralogs for CTXN2 Gene

Selected SIMAP similar genes for CTXN2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CTXN2: view

Variants for CTXN2 Gene

Sequence variations from dbSNP and Humsavar for CTXN2 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1320050 -- 48,188,011(+) ATTTT(C/T)TGTAT intron-variant
rs1320051 -- 48,188,238(+) AAGAA(A/G)AGATA intron-variant
rs1320052 -- 48,203,311(+) CATAT(C/T)TGTTA utr-variant-3-prime
rs2413886 -- 48,186,023(+) TGCTC(G/T)TGTTT intron-variant
rs2413887 -- 48,193,729(+) GACTT(C/T)TGTTT intron-variant

Relevant External Links for CTXN2 Gene

HapMap Linkage Disequilibrium report
CTXN2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CTXN2 Gene

Disorders for CTXN2 Gene

(2) University of Copenhagen DISEASES for CTXN2 Gene

genes like me logo Genes that share disorders with CTXN2: view

No data available for UniProtKB/Swiss-Prot for CTXN2 Gene

Publications for CTXN2 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3 4
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for CTXN2 Gene

Sources for CTXN2 Gene

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