Aliases for CTU1 Gene
External Ids for CTU1 Gene
Previous HGNC Symbols for CTU1 Gene
Previous GeneCards Identifiers for CTU1 Gene
GeneCards Summary for CTU1 Gene
CTU1 (Cytosolic Thiouridylase Subunit 1) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA modification in the nucleus and cytosol. GO annotations related to this gene include tRNA binding and nucleotidyltransferase activity.
UniProtKB/Swiss-Prot for CTU1 Gene
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.