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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CTTNBP2 Gene

protein-coding   GIFtS: 55
GCID: GC07M117350

Cortactin Binding Protein 2

(Previous name: cortactin binding protein 2)
(Previous symbols: CORTBP2, C7orf8)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cortactin Binding Protein 21 2     Orf42
CORTBP21 2 3 5     Cortactin-Binding Protein 22
C7orf81 2 3     CortBP23
KIAA17583 5     

External Ids:    HGNC: 156791   Entrez Gene: 839922   Ensembl: ENSG000000770637   OMIM: 6097725   UniProtKB: Q8WZ743   

Export aliases for CTTNBP2 gene to outside databases

Previous GC identifers: GC07M116906 GC07M116944 GC07M117137 GC07M111716


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CTTNBP2 Gene:
This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat
interacts with a central regulator of the actin cytoskeleton. (provided by RefSeq, Jul 2008)

GeneCards Summary for CTTNBP2 Gene: 
CTTNBP2 (cortactin binding protein 2) is a protein-coding gene. Diseases associated with CTTNBP2 include cerebral cavernous malformations 3, and cavernous malformation. GO annotations related to this gene include SH3 domain binding. An important paralog of this gene is CTTNBP2NL.

UniProtKB/Swiss-Prot: CTTB2_HUMAN, Q8WZ74
Function: Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls
dendritic spinogenesis and dendritic spine maintenance (By similarity)

Gene Wiki entry for CTTNBP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTTNBP2 gene promoter:
         E2F-4   E2F-3a   HFH-3   RFX1   E2F-5   Nkx2-5   E2F-2   FOXI1   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CTTNBP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CTTNBP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTTNBP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31   Ensembl cytogenetic band:  7q31.31   HGNC cytogenetic band: 7q31

CTTNBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTTNBP2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M117350:  view genomic region     (about GC identifiers)

Start:
117,350,705 bp from pter      End:
117,514,193 bp from pter
Size:
163,489 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 116,746,141-116,908,979     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CTTB2_HUMAN, Q8WZ74 (See protein sequence)
Recommended Name: Cortactin-binding protein 2  
Size: 1663 amino acids; 181051 Da
Subunit: Interacts with CTTN/cortactin SH3 domain (By similarity). Interacts with STRN, STRN4/zinedin and
MOB4/phocein; this interaction may regulate dendritic spine distribution of STRN and STRN4 in hippocampal neurons
(By similarity). Activation of glutamate receptors weakens the interaction with STRN and STRN4 (By similarity)
Subcellular location: Cytoplasm, cell cortex (By similarity). Cell projection, dendritic spine (By similarity).
Note=Remains associated with dendritic spines even after glutamate stimulation (By similarity)
Secondary accessions: O43389 Q7LG11 Q9C0A5

Explore the universe of human proteins at neXtProt for CTTNBP2: NX_Q8WZ74

Explore proteomics data for CTTNBP2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WZ74

  • CTTNBP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CTTNBP2 Protein Expression
    REFSEQ proteins: NP_219499.1  
    ENSEMBL proteins: 
     ENSP00000160373   ENSP00000389576   ENSP00000397678   ENSP00000389491   ENSP00000395925  
     ENSP00000406142   ENSP00000396014   ENSP00000405831   ENSP00000393373  

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    Cloud-Clone Corp. Proteins for CTTNBP2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005938cell cortex IEA--
    GO:0008021synaptic vesicle IEA--
    GO:0043197dendritic spine IEA--

    CTTNBP2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR019131 Cortactin-binding_p2_N
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q8WZ74

    ProtoNet protein and cluster: Q8WZ74

    1 Blocks protein domain: IPB001064 Beta and gamma crystallin

    UniProtKB/Swiss-Prot: CTTB2_HUMAN, Q8WZ74
    Similarity: Contains 6 ANK repeats


    CTTNBP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CTTB2_HUMAN, Q8WZ74
    Function: Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls
    dendritic spinogenesis and dendritic spine maintenance (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0017124SH3 domain binding IEA--
         
    CTTNBP2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CTTNBP2:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTTNBP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/25 Interacting proteins for CTTNBP2 (Q8WZ743 ENSP000001603734) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCT8P509903, ENSP000002867884I2D: score=2 STRING: ENSP00000286788
    CTTNBP2NLQ9P2B43, ENSP000002712774I2D: score=2 STRING: ENSP00000271277
    PPP2CBP627143, ENSP000002211384I2D: score=2 STRING: ENSP00000221138
    PPP2R1AP301533, ENSP000003248044I2D: score=2 STRING: ENSP00000324804
    STK24Q9Y6E03, ENSP000003657304I2D: score=2 STRING: ENSP00000365730
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007420brain development IEA--

    CTTNBP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CTTNBP2 (CTTB2)

    Search CenterWatch for drugs/clinical trials and news about CTTNBP2 / CTTB2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CTTNBP2 gene: 
    NM_033427.2  

    Unigene Cluster for CTTNBP2:

    Cortactin binding protein 2
    Hs.592285  [show with all ESTs]
    Unigene Representative Sequence: NM_033427
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000160373(uc003vjf.3) ENST00000446636 ENST00000441556 ENST00000445366
    ENST00000435233 ENST00000482124 ENST00000416239 ENST00000467088 ENST00000434890
    ENST00000487820 ENST00000454375 ENST00000412853
    miRNA
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    hsa-miR-92a hsa-miR-137 hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-135b hsa-miR-363 hsa-miR-101
    SwitchGear 3'UTR luciferase reporter plasmidCTTNBP2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB051545.1 AF377960.1 AK091548.1 AK096565.1 AK308081.1 BC019644.1 BC106000.1 

    6 DOTS entries:

    DT.452364  DT.40292735  DT.100640891  DT.121054004  DT.40204792  DT.92060230 

    24/50 AceView cDNA sequences (see all 50):

    Z41481 AA323075 AL137685 Z43352 F08491 AL713390 CD678319 BM686003 
    BX952377 AK096565 CB269603 CD677746 BC019644 BM663650 AF377960 F02895 
    BG165144 Z43555 Z39427 R73966 AI274589 CD635151 AA780250 BX493843 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CTTNBP2 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^
    SP1:              -     -                                                           -                             -                 -                           
    SP2:                                                                                                              -                                             
    SP3:                                                                                                              -                 -     -                     
    SP4:                                                                                                                                                            
    SP5:                    -                                                                                                                                       

    ExUns: 20 ^ 21a · 21b ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:                    -                                 
    SP5:                                                      


    ECgene alternative splicing isoforms for CTTNBP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CTTNBP2 expression in normal human tissues (normalized intensities)      CTTNBP2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CTTNBP2 Expression
    About this image


    CTTNBP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Thalamus
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Endothelium (Cardiovascular System)
             Endothelial progenitor cells ( Derivation and purification of endothelial precursor...

    See CTTNBP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CTTNBP2

    SOURCE GeneReport for Unigene cluster: Hs.592285

    UniProtKB/Swiss-Prot: CTTB2_HUMAN, Q8WZ74
    Tissue specificity: Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal
    muscle and placenta

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CTTNBP2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cttnbp21 , 5 cortactin binding protein 21, 5 86.87(n)1
    85.97(a)1
      6 (8.12 cM)5
    307851  NM_080285.11  NP_525024.11 
     183664785 
    chicken
    (Gallus gallus)
    Aves CTTNBP21 cortactin binding protein 2 77.12(n)
    74.07(a)
      417766  NM_001098539.1  NP_001092009.1 
    lizard
    (Anolis carolinensis)
    Reptilia CTTNBP26
    Uncharacterized protein
    68(a)
    1 ↔ 1
    5(61655815-61723515)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.238842 Xenopus laevis transcribed sequence with weak similarity to protein refNP_219499.1 (H.sapiens) cortactin-binding protein 2 [Homo sapiens] less 76.03(n)    CD301000.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cttnbp21 cortactin binding protein 2 58.68(n)
    52.12(a)
      555837  XM_678481.3  XP_683573.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG109156
    --
    22(a)
    1 → many
    2R(14048225-14051714)


    ENSEMBL Gene Tree for CTTNBP2 (if available)
    TreeFam Gene Tree for CTTNBP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CTTNBP2 gene
    CTTNBP2NL2  FILIP12  FILIP1L2  LUZP12  
    3 SIMAP similar genes for CTTNBP2 using alignment to 14 protein entries:     CTTB2_HUMAN (see all proteins):
    CTTNBP2NL    PPP1R12A    DKFZp547A023

    CTTNBP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3085 SNPs in CTTNBP2 are shown (see all 3085)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1460388411,2
    Cuntested1116770561(+) CTCATA/C/GAAAGT 2 H Y mis10--------
    rs1483782981,2
    --116745680(+) AAAAAC/TCACAT 1 -- ds50010--------
    rs1495932111,2
    C--116745717(+) TATGA-/TTTTTG 1 -- ds50010--------
    rs1415032721,2
    C--116745834(+) ACTTCA/GTTGTA 1 -- ds50010--------
    rs1813439431,2
    --116745846(+) ATAACC/GATTCT 1 -- ds50010--------
    rs1862534591,2
    --116746011(+) GGGTTA/GAGTCT 1 -- ds50010--------
    rs1911756221,2
    --116746069(+) GAGCAC/TTGATA 1 -- ds50010--------
    rs1116722131,2
    F--116746098(+) TGTTAC/TAGAGA 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1462860601,2
    C--116746192(+) ATTGT-/GTAA  
            
    GTAAT
    1 -- ut310--------
    rs1859805161,2
    --116746192(+) ATTGTA/GTAAGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CTTNBP2 (117350705 - 117514193 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for CTTNBP2 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2735065CNV Deletion23290073
    esv1000466CNV Deletion20482838
    esv2735066CNV Deletion23290073
    esv270367CNV Insertion20981092
    esv274057CNV Insertion20981092
    nsv5918CNV Insertion18451855
    esv272004CNV Insertion20981092
    esv2533512CNV Insertion19546169
    esv1717444CNV Insertion17803354
    nsv464695CNV Loss19166990


    Human Gene Mutation Database (HGMD): CTTNBP2
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609772    OMIM disorders: --

    4 diseases for CTTNBP2:    About MalaCards
    cerebral cavernous malformations 3    cavernous malformation    cerebral cavernous malformation    cerebritis

    1 disease from the University of Copenhagen DISEASES database for CTTNBP2:
    Weaver syndrome

    CTTNBP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CTTNBP2
    Human Genome Epidemiology (HuGE) Navigator: CTTNBP2 (1 document)

    Export disorders for CTTNBP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CTTNBP2 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with CTTNBP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the human cortactin-binding protein-2 gene from the autism candidate region at 7q31. (PubMed id 11707066)1, 2, 3, 9 Cheung J....Scherer S.W. (2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    5. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
    6. A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein. (PubMed id 18782753)1, 9 Goudreault M....Gingras A.C. (2009)
    7. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    8. HectD1 E3 ligase modifies adenomatous polyposis coli ( APC) with polyubiquitin to promote the APC-axin interaction. (PubMed id 23277359)1 Tran H....Polakis P. (2013)
    9. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83992 HGNC: 15679 AceView: CTTNBP2 Ensembl:ENSG00000077063 euGenes: HUgn83992
    ECgene: CTTNBP2 H-InvDB: CTTNBP2

    (According to HUGE)
    About This Section
    HUGE: KIAA1758

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CTTNBP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CTTNBP2 gene:
    Search GeneIP for patents involving CTTNBP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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