Aliases for CTSZ Gene
External Ids for CTSZ Gene
Previous GeneCards Identifiers for CTSZ Gene
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008]
GeneCards Summary for CTSZ Gene
CTSZ (Cathepsin Z) is a Protein Coding gene. Diseases associated with CTSZ include Dacryoadenitis. Among its related pathways are Peptide hormone metabolism and Clathrin derived vesicle budding. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity. An important paralog of this gene is CTSC.
UniProtKB/Swiss-Prot for CTSZ Gene
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.