Aliases for CTSW Gene
External Ids for CTSW Gene
Previous GeneCards Identifiers for CTSW Gene
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTSW Gene
CTSW (Cathepsin W) is a Protein Coding gene. Diseases associated with CTSW include autoimmune atrophic gastritis. Among its related pathways are Platelet activation, signaling and aggregation and Lysosome. GO annotations related to this gene include cysteine-type peptidase activity. An important paralog of this gene is CTSO.
UniProtKB/Swiss-Prot for CTSW Gene
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.