Aliases for CTSV Gene
External Ids for CTSV Gene
Previous HGNC Symbols for CTSV Gene
Previous GeneCards Identifiers for CTSV Gene
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]
GeneCards Summary for CTSV Gene
CTSV (Cathepsin V) is a Protein Coding gene. Diseases associated with CTSV include osteoarthritis and atherosclerosis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Endochondral Ossification. GO annotations related to this gene include protein complex binding and cysteine-type endopeptidase activity. An important paralog of this gene is CTSW.
UniProtKB/Swiss-Prot for CTSV Gene
Cysteine protease. May have an important role in corneal physiology.