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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CTSO Gene

protein-coding   GIFtS: 55
GCID: GC04M156845

Cathepsin O


(Previous symbol: CTSO1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cathepsin O1 2
CTSO11 2 3
EC 3.4.22.423

External Ids:    HGNC: 25421   Entrez Gene: 15192   Ensembl: ENSG000002560437   OMIM: 6005505   UniProtKB: P432343   

Export aliases for CTSO gene to outside databases

Previous GC identifers: GC04M157734 GC04M157274 GC04M157422 GC04M157202 GC04M157064 GC04M152584


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CTSO Gene:
The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic
enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to
degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was
abolished by an inhibitor of cyteine proteinase. (provided by RefSeq, Jul 2008)

GeneCards Summary for CTSO Gene: 
CTSO (cathepsin O) is a protein-coding gene. Diseases associated with CTSO include pycnodysostosis, and among its related super-pathways are Immune System and Kinesins. GO annotations related to this gene include cysteine-type endopeptidase activity. An important paralog of this gene is TINAG.

UniProtKB/Swiss-Prot: CATO_HUMAN, P43234
Function: Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover

Gene Wiki entry for CTSO (Cathepsin O) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CTSO
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCTSO promoter sequence
   Search SABiosciences Chromatin IP Primers for CTSO

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTSO


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q32.1   Ensembl cytogenetic band:  4q32.1   HGNC cytogenetic band: 4q32.1

CTSO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTSO gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M156845:  view genomic region     (about GC identifiers)

Start:
156,845,270 bp from pter      End:
156,875,069 bp from pter
Size:
29,800 bases      Orientation:
minus strand

1 alternative location:
Chr4-,NW_003315914 88,741-118,513     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CATO_HUMAN, P43234 (See protein sequence)
Recommended Name: Cathepsin O precursor  
Size: 321 amino acids; 35958 Da
Subcellular location: Lysosome

Explore the universe of human proteins at neXtProt for CTSO: NX_P43234

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P43234

  • CTSO Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins: NP_001325.1  
    ENSEMBL proteins: 
     ENSP00000414904  
    Reactome Protein details: P43234
    Human Recombinant Protein Products for CTSO: 
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    Novus Biologicals CTSO Protein
    Novus Biologicals CTSO Lysate
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CTSO 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IEA--

    CTSO for ontologies           About GeneDecksing



    CTSO Antibody Products: 
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    Cloud-Clone Corp. CLIAs for CTSO


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CTS: Cathepsins

    4 InterPro protein domains:
     IPR013128 Peptidase_C1A
     IPR000169 Pept_cys_AS
     IPR025660 Pept_his_AS
     IPR000668 Peptidase_C1A_C

    Graphical View of Domain Structure for InterPro Entry P43234

    ProtoNet protein and cluster: P43234

    1 Blocks protein domain: IPB000668 Papain cysteine protease (C1) family signature

    UniProtKB/Swiss-Prot: CATO_HUMAN, P43234
    Similarity: Belongs to the peptidase C1 family


    CTSO for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CATO_HUMAN, P43234
    Function: Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover
    Catalytic activity: The recombinant human enzyme hydrolyzes synthetic endopeptidase substrates including
    Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec

         Genatlas biochemistry entry for CTSO:
    cathepsin O,lysosomal cysteine proteinase,papain superfamily,ubiquitously expressed

         Enzyme Number (IUBMB): EC 3.4.22.421

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004197cysteine-type endopeptidase activity TAS7929457
    GO:0008234cysteine-type peptidase activity ----
         
    CTSO for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CTSO 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CTSO 
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    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate CTSO:
    hsa-miR-578 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidCTSO 3' UTR sequence
    Inhib. RNA
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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CTSO About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Immune System
    Immune System0.56
    Adaptive Immune System0.56
    2MHC class II antigen presentation
    MHC class II antigen presentation0.32
    3Lysosome
    Lysosome

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3        Reactome Pathways for CTSO
        Adaptive Immune System
    Immune System
    MHC class II antigen presentation


    1         Kegg Pathway  (Kegg details for CTSO):
        Lysosome


    CTSO for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTSO

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--

    CTSO for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CTSO (CATO)

    Search CenterWatch for drugs/clinical trials and news about CTSO / CATO

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CTSO gene: 
    NM_001334.2  

    Unigene Cluster for CTSO:

    Cathepsin O
    Hs.75262  [show with all ESTs]
    Unigene Representative Sequence: NM_001334
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000433477(uc003ipg.3)
    miRNA
    Products:
         
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate CTSO:
    hsa-miR-578 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidCTSO 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CTSO
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CTSO
    Clone
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    OriGene clones in human, mouse for CTSO (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CTSO (NM_001334)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CTSO
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTSO
    Sirion Biotech Customized lentivirus for stable overexpression of CTSO 
                         Customized lentivirus expression plasmids for stable overexpression of CTSO 
    Primer
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    OriGene qPCR primer pairs and template standards for CTSO
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CTSO
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CTSO

    Additional mRNA sequence: 

    AK300112.1 AK308323.1 AK312354.1 BC049206.1 X77383.1 

    4 DOTS entries:

    DT.452446  DT.121218744  DT.100809660  DT.40191333 

    24/138 AceView cDNA sequences (see all 138):

    BX956104 AA885288 AI634956 AI247006 AI348405 BE219235 AI247114 AI889600 
    BX113588 AA922992 AA024431 AI570168 BM129303 AI523707 CK819570 AI708625 
    AI522027 AI192248 BM998065 AI635547 AW305190 AA024432 AA767784 BU735518 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CTSO expression in normal human tissues (normalized intensities)      CTSO embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATGCAGTA
    CTSO Expression
    About this image


    CTSO expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)
             Umbilical cord blood-derived endothelial progenitor cells
     
     Endothelium (Cardiovascular System)
             Umbilical cord blood-derived endothelial progenitor cells
     
     Bone (Muscoskeletal System)
             Human fetal bone marrow-derived mesenchymal stromal cells
     
     Neural Tube (Nervous System)
             Metencephalon

    Genevestigator expression for CTSO

    SOURCE GeneReport for Unigene cluster: Hs.75262

    UniProtKB/Swiss-Prot: CATO_HUMAN, P43234
    Tissue specificity: Expressed in all tissues examined. High levels seen in the ovary, kidney and placenta while
    low levels seen in thymus and skeletal muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTSO

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CTSO gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ctso1 , 5 cathepsin O1, 5 80.16(n)1
    76.82(a)1
      3 (35.97 cM)5
    2294451  NM_177662.21  NP_808330.11 
     819326015 
    chicken
    (Gallus gallus)
    Aves CTSO1 cathepsin O 74.06(n)
    72.54(a)
      422410  NM_001031129.1  NP_001026300.1 
    lizard
    (Anolis carolinensis)
    Reptilia CTSO6
    Uncharacterized protein
    67(a)
    1 ↔ 1
    5(129429266-129445037)
    zebrafish
    (Danio rerio)
    Actinopterygii ctso1 cathepsin O 60.79(n)
    57.55(a)
      567333  XM_690625.4  XP_695717.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG53676
    CG63476
    (see all 4)
    --
    25(a)
    24(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    2L(10354743-10356597)
    2R(9723926-9726869)
    worm
    (Caenorhabditis elegans)
    Secernentea R07E3.13 cysteine proteinase 33(a)   X(10374605-10376330)   --


    ENSEMBL Gene Tree for CTSO (if available)
    TreeFam Gene Tree for CTSO (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CTSO gene
    TINAG2  CTSF2  CTSW2  CTSV2  CTSK2  CTSB2  CTSS2  CTSH2  
    CTSC2  TINAGL12  CTSZ2  CTSL2  
    7 SIMAP similar genes for CTSO using alignment to 1 protein entry:     CATO_HUMAN:
    CTSS    CTSF    CTSK    CTSL2    CTSL1    CTSW
    CTSH

    CTSO for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/750 SNPs in CTSO are shown (see all 750)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1440353541,2
    --156844788(+) TAAATA/GCAGGG 1 -- ds50010--------
    rs1473741391,2
    --156844949(+) GGAGGC/TAGGTA 1 -- ds50010--------
    rs1484363391,2
    --156845034(+) TGATTC/GCATAA 1 -- ds50010--------
    rs780429191,2
    C--156845084(+) AAGGAA/CATTTT 1 -- ds50010--------
    rs1916809071,2
    --156845099(+) GGGGGA/TGGTGG 1 -- ds50010--------
    rs782421931,2
    F--156845144(+) AAACAC/GTGAGG 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1841466631,2
    C--156845253(+) AAGCCA/GTACAC 1 -- ds50010--------
    rs1491130911,2
    --156845414(+) CACAT-/AGAAA 
    GTCAGCGA
    AGAAA
    1 -- ut310--------
    rs1873256811,2
    --156845436(+) CAAACG/TAGACA 1 -- ut310--------
    rs1505121261,2
    --156845556(+) CTTTTC/TGGATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CTSO (156845270 - 156875069 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CTSO:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv999516CNV Insertion20482838
    nsv4564CNV Insertion18451855
    nsv262CNV Insertion15895083
    nsv437447CNV Loss16327808
    esv274871CNV Loss21479260
    nsv830121CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for CTSO

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600550    OMIM disorders: --

    2 diseases for CTSO:    About MalaCards
    pycnodysostosis    


    CTSO for disorders           About GeneDecksing

    Genetic Association Database (GAD): CTSO

    Export disorders for CTSO gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CTSO gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CTSO)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure and chromosomal localization of the human cathepsin O gene (CTSO). (PubMed id 9790772)1, 3, 9 Santamaria I....Lopez-Otin C. (1998)
    2. First genome-wide association scan on neurophysiologi cal endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic chi ldren. (PubMed id 19786962)1, 4 Roeske D....Schulte-KAPrne G. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues. (PubMed id 7929457)1, 2 Velasco G.... Lopez-Otin C. (1994)
    5. Molecular insight into propeptide-protein interactions in cathepsins L and O. (PubMed id 23009386)1 Reif M.M....Oostenbrink C. (2012)
    6. Proteomics strategy to identify substrates of LNX, a P DZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)1 Guo Z....Gao Y. (2012)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2. (PubMed id 7805878)1 Shi G.-P....Weiss S.J. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1519 HGNC: 2542 AceView: CTSO Ensembl:ENSG00000256043 euGenes: HUgn1519
    ECgene: CTSO Kegg: 1519 H-InvDB: CTSO

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CTSO Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CTSO gene:
    Search GeneIP for patents involving CTSO

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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