Aliases for CTSH Gene
External Ids for CTSH Gene
Previous Symbols for CTSH Gene
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq, Mar 2010]
GeneCards Summary for CTSH Gene
CTSH (Cathepsin H) is a Protein Coding gene. Diseases associated with CTSH include thyroid crisis and narcolepsy. Among its related pathways are Class I MHC mediated antigen processing and presentation and Lysosome. GO annotations related to this gene include serine-type endopeptidase activity and cysteine-type peptidase activity. An important paralog of this gene is CTSW.
UniProtKB/Swiss-Prot for CTSH Gene
Important for the overall degradation of proteins in lysosomes