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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CTRB2 Gene

protein-coding   GIFtS: 46
GCID: GC16M075237

Chymotrypsinogen B2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chymotrypsinogen B21 2
EC 3.4.21.13 8
Chymotrypsin B22
EC 3.4.218

External Ids:    HGNC: 25221   Entrez Gene: 4403872   Ensembl: ENSG000001689287   UniProtKB: Q6GPI13   

Export aliases for CTRB2 gene to outside databases

Previous GC identifers: GC00U990074 GC16M073796 GC16M060989


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CTRB2 Gene: 
CTRB2 (chymotrypsinogen B2) is a protein-coding gene. Diseases associated with CTRB2 include acute pancreatitis, and pancreatitis, and among its related super-pathways are Degradation of collagen and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is CTRL.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTRB2 gene promoter:
         NF-1   GATA-3   Tal-1beta   SREBP-1b   GATA-2   GATA-1   PPAR-gamma1   SREBP-1a   PPAR-gamma2   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCTRB2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CTRB2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTRB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.1   Ensembl cytogenetic band:  16q23.1   HGNC cytogenetic band: 16q22.3

CTRB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTRB2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M075237:  view genomic region     (about GC identifiers)

Start:
75,237,994 bp from pter      End:
75,241,083 bp from pter
Size:
3,090 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CTRB2_HUMAN, Q6GPI1 (See protein sequence)
Recommended Name: Chymotrypsinogen B2 precursor  
Size: 263 amino acids; 27923 Da
Subcellular location: Secreted, extracellular space
Secondary accessions: A8K707

Explore the universe of human proteins at neXtProt for CTRB2: NX_Q6GPI1

Explore proteomics data for CTRB2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6GPI1

  • 4/10 DME Specific Peptides for CTRB2 (Q6GPI1) (see all 10)
     SGGPLVC  GDSGGPL  FCGGSLI  WPWQVSL 

    CTRB2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CTRB2 Protein Expression
    REFSEQ proteins: NP_001020371.3  
    ENSEMBL proteins: 
     ENSP00000303963   ENSP00000454599   ENSP00000457279   ENSP00000455207  
    Reactome Protein details: Q6GPI1
    Human Recombinant Protein Products for CTRB2: 
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    OriGene Protein Over-expression Lysate for CTRB2
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CTRB2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--

    CTRB2 for ontologies           About GeneDecksing



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    Assay Products for CTRB2: 
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    Cloud-Clone Corp. ELISAs for CTRB2 
    Cloud-Clone Corp. CLIAs for CTRB2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR001314 Peptidase_S1A
     IPR001254 Peptidase_S1
     IPR018114 Peptidase_S1_AS
     IPR009003 Trypsin-like_Pept_dom

    Graphical View of Domain Structure for InterPro Entry Q6GPI1

    ProtoNet protein and cluster: Q6GPI1

    2 Blocks protein domains:
    IPB001254 Serine protease
    IPB001314 Chymotrypsin serine protease family (S1) signature


    UniProtKB/Swiss-Prot: CTRB2_HUMAN, Q6GPI1
    Similarity: Belongs to the peptidase S1 family
    Similarity: Contains 1 peptidase S1 domain


    CTRB2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CTRB2_HUMAN, Q6GPI1
    Catalytic activity: Preferential cleavage: Tyr- -Xaa, Trp- -Xaa, Phe- -Xaa, Leu- -Xaa

         Enzyme Numbers (IUBMB): EC 3.4.21.11 2 EC 3.4.212

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004252serine-type endopeptidase activity IEA--
         
    CTRB2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CTRB2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CTRB2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CTRB2 
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    miRNA
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    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: CTRB2 (NM_001025200)
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    Search LifeMap BioReagents cell lines for CTRB2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTRB2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CTRB2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Degradation of the extracellular matrix
    Degradation of the extracellular matrix0.79
    Activation of Matrix Metalloproteinases0.40
    2Metabolism of vitamins and cofactors
    Metabolism of water-soluble vitamins and cofactors1.00
    Metabolism of vitamins and cofactors1.00
    3Metabolism
    Metabolism0.40
    4Collagen biosynthesis and modifying enzymes
    Extracellular matrix organization0.39
    5Cobalamin (Cbl, vitamin B12) transport and metabolism
    Cobalamin (Cbl, vitamin B12) transport and metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/7        Reactome Pathways for CTRB2 (see all 7)
        Extracellular matrix organization
    Metabolism
    Cobalamin (Cbl, vitamin B12) transport and metabolism
    Metabolism of vitamins and cofactors
    Degradation of the extracellular matrix



    CTRB2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTRB2

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0006766vitamin metabolic process TAS--
    GO:0006767water-soluble vitamin metabolic process TAS--
    GO:0007586digestion IEA--
    GO:0009235cobalamin metabolic process TAS--

    CTRB2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CTRB2

    Search CenterWatch for drugs/clinical trials and news about CTRB2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CTRB2 gene: 
    NM_001025200.3  

    Unigene Cluster for CTRB2:

    Chymotrypsinogen B2
    Hs.632211  [show with all ESTs]
    Unigene Representative Sequence: BF676199
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000303037(uc002fdr.3) ENST00000562106 ENST00000567767 ENST00000562387
    ENST00000481611 ENST00000565656
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CTRB2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CTRB2
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CTRB2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CTRB2
    Clone
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    OriGene clones in human, mouse for CTRB2 (see all 5)
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    GenScript: all cDNA clones in your preferred vector: CTRB2 (NM_001025200)
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    Sirion Biotech Customized lentivirus for stable overexpression of CTRB2 
                         Customized lentivirus expression plasmids for stable overexpression of CTRB2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CTRB2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CTRB2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CTRB2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CTRB2

    Additional mRNA sequence: 

    AK131056.1 AK225933.1 AK291822.1 BC073145.1 

    13 DOTS entries:

    DT.92421819  DT.99939380  DT.120699689  DT.120699706  DT.450700  DT.100820255  DT.100820256  DT.100820257 
    DT.120699696  DT.40221398  DT.100820247  DT.100820254  DT.120699704 

    24/375 AceView cDNA sequences (see all 375):

    BQ776388 BU948857 BQ271426 BM505391 BU078137 AA366241 CA943664 BM090602 
    CA947063 CA941208 AA366236 BU784594 CA941501 BI712390 AA367430 BU072031 
    BM272082 BU950135 BM263839 AA366672 W52845 CA867847 CA866166 AA844977 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CTRB2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7
    SP1:                                                            
    SP2:                                                            
    SP3:                                            -     -         


    ECgene alternative splicing isoforms for CTRB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CTRB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTTCCTCT
    CTRB2 Expression
    About this image


    See CTRB2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CTRB2

    SOURCE GeneReport for Unigene cluster: Hs.632211
        SABiosciences Custom PCR Arrays for CTRB2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTRB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CTRB2 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ctrb11 chymotrypsinogen B1 83.9(n)
    85.17(a)
      66473  NM_025583.2  NP_079859.2 
    chicken
    (Gallus gallus)
    Aves LOC4312351 chymotrypsinogen 2-like 71.74(n)
    69.2(a)
      431235  XM_003641893.1  XP_003641941.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    67(a)
    1 → many
    GL343840.1(1393-8494)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1364611 zgc:136461 70.09(n)
    66.54(a)
      692313  NM_001045282.1  NP_001038747.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Jon99Cii6
    Jon99Ciii6
    (see all 33)
    Jonah 99Ciii
    (see all 33)
    29(a)
    29(a)
    (see all 33)
    many ↔ many
    many ↔ many
    (see all 33)
    3R(25749476-25750337)
    3R(25747938-25748774)


    ENSEMBL Gene Tree for CTRB2 (if available)
    TreeFam Gene Tree for CTRB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CTRB2 gene
    CTRL2  CTRC2  CELA2A2  CELA3B2  CELA12  CTRB12  CELA3A2  CELA2B2  
    OVCH22  OVCH12  
    18/113 SIMAP similar genes for CTRB2 using alignment to 4 protein entries:     CTRB2_HUMAN (see all proteins) (see all similar genes):
    CTRB1    CTRL    FLJ00366    PRSS1    TMPRSS5    TMPRSS3
    CELA1    CELA3B    TMPRSS15    TMPRSS9    serase-1B    CELA2A
    ELA2A    CELA2B    DF    ELA2B    KLKB1    OVCH1

    CTRB2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CTRB2
    PGOHUM00000262504


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/190 SNPs in CTRB2 are shown (see all 190)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs569746081,2
    C,F--75237592(+) AGGTGT/CGAGGG 1 -- int16Minor allele frequency- C:0.21NA CSA WA EA 363
    rs1501993461,2
    --75237655(+) TGGACA/TTGGGG 1 -- int10--------
    rs1114184021,2
    C--75237658(+) ACATGA/GGGGAC 1 -- int10--------
    rs1128994901,2
    F--75237800(+) CAGCAG/AGTAGG 1 -- int11Minor allele frequency- A:0.50CSA 4
    rs1387376961,2
    C--75237811(+) GCCTAA/CATTCT 1 -- int10--------
    rs116473801,2
    C,H--75237824(+) ACCCAA/G/TGGTGG 1 -- int10--------
    rs800536421,2
    F--75237838(+) CGTGAG/CCAGGC 1 -- int11Minor allele frequency- C:0.08WA 118
    rs116473881,2
    H--75237863(+) CCTCAG/TCTTCC 1 -- int10--------
    rs1161241881,2
    F--75237914(+) GGGAAC/TGGTAG 1 -- int11Minor allele frequency- T:0.04WA 118
    rs2005812851,2
    C--75238055(+) GCTGCA/GGGCTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CTRB2 (75237994 - 75241083 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for CTRB2 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv523405CNV Loss19592680
    dgv2912n71CNV Loss21882294
    nsv482197CNV Gain20164927
    nsv833282CNV Gain+Loss17160897
    nsv516504CNV Gain+Loss19592680
    esv2504659OTHER Inversion19546169
    dgv20n50OTHER Inversion21212237
    dgv51n16OTHER Inversion17901297
    esv1356452OTHER Inversion17803354
    dgv25n47OTHER Inversion21111241

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CTRB2
    DNA2.0 Custom Variant and Variant Library Synthesis for CTRB2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for CTRB2:    About MalaCards
    acute pancreatitis    pancreatitis


    CTRB2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CTRB2
    Human Genome Epidemiology (HuGE) Navigator: CTRB2 (1 document)

    Export disorders for CTRB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CTRB2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CTRB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic cloning and partial characterization of human chymotrypsinogen gene. (PubMed id 8186414)1, 3 Hou D.X....Soeda E. (1993)
    2. Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA. (PubMed id 2917002)1, 3 Tomita N.... Matsubara K. (1989)
    3. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. (PubMed id 19430480)4 Barrett J.C....Rich S.S. (2009)
    4. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
    5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 440387 HGNC: 2522 AceView: LOC440387 Ensembl:ENSG00000168928 euGenes: HUgn440387
    ECgene: CTRB2 H-InvDB: CTRB2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CTRB2 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Chymotrypsin

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CTRB2 gene:
    Search GeneIP for patents involving CTRB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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