Aliases for CTRB1 Gene
External Ids for CTRB1 Gene
Previous HGNC Symbols for CTRB1 Gene
Previous GeneCards Identifiers for CTRB1 Gene
This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2016]
GeneCards Summary for CTRB1 Gene
CTRB1 (Chymotrypsinogen B1) is a Protein Coding gene. Diseases associated with CTRB1 include Common Bile Duct Disease. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is CTRB2.