Aliases for CTNNBL1 Gene
External Ids for CTNNBL1 Gene
Previous HGNC Symbols for CTNNBL1 Gene
Previous GeneCards Identifiers for CTNNBL1 Gene
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
GeneCards Summary for CTNNBL1 Gene
CTNNBL1 (Catenin Beta Like 1) is a Protein Coding gene. Diseases associated with CTNNBL1 include Auditory Agnosia and Periodic Limb Movement Disorder. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. GO annotations related to this gene include binding and enzyme binding.
UniProtKB/Swiss-Prot for CTNNBL1 Gene
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.