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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CTNNBIP1 Gene

protein-coding   GIFtS: 57
GCID: GC01M009908

catenin, beta interacting protein 1

(Previous names: catenin, beta-interacting protein 1 )
 Explore 25 diseases affiliated with
CTNNBIP1 via
MalaCards
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 Human Malady Compendium 
Biological research products
for CTNNBIP1    

Aliases
for CTNNBIP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Catenin, Beta Interacting Protein 11 2     Catenin, Beta-Interacting Protein 11
ICAT1 2 3 5     Beta-Catenin-Interacting Protein 12
Inhibitor Of Beta-Catenin And Tcf-42 3     Beta-Catenin-Interacting Protein ICAT2
MGC150931     

External Ids:    HGNC: 169131   Entrez Gene: 569982   Ensembl: ENSG000001785857   OMIM: 6077585   UniProtKB: Q9NSA33   
ORGUL members:         
NONCODE:n337710    

Export aliases for CTNNBIP1 gene to outside databases

Previous GC identifers: GC01M009869 GC01M009752 GC01M009517 GC01M009617 GC01M009842 GC01M009064


Summaries
for CTNNBIP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CTNNBIP1:
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The
encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same
protein have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CNBP1_HUMAN, Q9NSA3
Function: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt
signaling pathway

Gene Wiki entry for CTNNBIP1


Genomic Views
for CTNNBIP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_021937.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTNNBIP1 gene promoter:
         E2F-4   E2F-3a   E2F-5   Sp1   p300   MyoD   E2F-2   E2F   E2F-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CTNNBIP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTNNBIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.22   Ensembl cytogenetic band:  1p36.22   HGNC cytogenetic band: 1pter-p36.31

CTNNBIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTNNBIP1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M009908:  view genomic region     (about GC identifiers)

Start:
 9,908,334 bp from pter      End:
 9,970,394 bp from pter
Size:
 62,061 bases      Orientation:
 minus strand

Proteins
for CTNNBIP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CNBP1_HUMAN, Q9NSA3 (See protein sequence)
Recommended Name: Beta-catenin-interacting protein 1  
Size: 81 amino acids; 9170 Da
Subunit: Binds CTNNB1
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
3 PDB 3D structures from and Proteopedia for CTNNBIP1:
1LUJ (3D)        1M1E (3D)        1T08 (3D)    
Secondary accessions: Q5T4V2

Explore the universe of human proteins at neXtProt for CTNNBIP1: NX_Q9NSA3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NSA3

    • CTNNBIP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001012329.1  NP_064633.1  

    ENSEMBL proteins: 
     ENSP00000366474   ENSP00000383696   ENSP00000366468   ENSP00000366466   ENSP00000444681  

    Human Recombinant Protein Products: 
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    Novus Biologicals CTNNBIP1 Proteins
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    ProSpec Recombinant Protein for CTNNBIP1
    Browse Proteins at Uscn

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA19569129
    GO:0005737cytoplasm IDA19569129
    GO:0005829cytosol IDA18287330
    GO:0030877beta-catenin destruction complex IDA16188939


    CTNNBIP1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CTNNBIP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CTNNBIP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009428 ICAT

    Graphical View of Domain Structure for InterPro Entry Q9NSA3

    ProtoNet protein and cluster: Q9NSA3

    UniProtKB/Swiss-Prot: CNBP1_HUMAN, Q9NSA3
    Similarity: Belongs to the CTNNBIP1 family


    Function
    for CTNNBIP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CNBP1_HUMAN, Q9NSA3
    Function: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt
    signaling pathway

    miRNA
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    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate CTNNBIP1 (see all 61):
    hsa-miR-4291 hsa-miR-3194-5p hsa-miR-328 hsa-miR-188-5p hsa-miR-15a hsa-miR-25 hsa-miR-29a hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CTNNBIP1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008013beta-catenin binding IPI12408825
    GO:0070016armadillo repeat domain binding IPI12408825


    CTNNBIP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CTNNBIP1:
     Decreased POU5F1-GFP protein e 

    Animal Models:
         Mouse knock-out Ctnnbip1tm1Taki for CTNNBIP1
         10 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ctnnbip1):
     cellular  craniofacial  digestive/alimentary  embryogenesis  mortality/aging 
     nervous system  renal/urinary system  respiratory system  skeleton  vision/eye 

    CTNNBIP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CTNNBIP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Wnt Signaling Pathway
    		Wnt signaling pathway0.30
    		Wnt Signaling Pathway NetPath0.22
    2Regulation of Wnt-mediated beta catenin signaling and target gene transcription
    		Regulation of Wnt-mediated beta catenin signaling and target gene transcription1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for CTNNBIP1 
        Wnt Signaling Pathway NetPath
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription


    1         Kegg Pathway  (Kegg details for CTNNBIP1):
        Wnt signaling pathway


    CTNNBIP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CTNNBIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/59 Interacting proteins for CTNNBIP1 (Q9NSA31, 2, 3 ENSP000003664664) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    JUPP149232, 3, ENSP000003111134MINT-68465 I2D: score=6 STRING: ENSP00000311113
    CTNNB1P352221, 2, 3, ENSP000003444564EBI-747082,EBI-491549 MINT-58679 I2D: score=9 STRING: ENSP00000344456
    BEND5Q7L4P63, ENSP000003608994I2D: score=4 STRING: ENSP00000360899
    CASP4P496623, ENSP000003885664I2D: score=2 STRING: ENSP00000388566
    CPVLQ9H3G53, ENSP000002653944I2D: score=2 STRING: ENSP00000265394
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0001658branching involved in ureteric bud morphogenesis IBA--
    GO:0002528regulation of vascular permeability involved in acute inflammatory response IMP18287330
    GO:0009952anterior/posterior pattern specification IBA--
    GO:0016055Wnt receptor signaling pathway IEA--


    CTNNBIP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CTNNBIP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CTNNBIP1
    Search CenterWatch for drugs/clinical trials and news about CTNNBIP1 / CNBP1 

    Transcripts
    for CTNNBIP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CTNNBIP1 gene (2 alternative transcripts): 
    NM_001012329.1  NM_020248.2  

    Unigene Cluster for CTNNBIP1:

    Catenin, beta interacting protein 1
    Hs.463759  [show with all ESTs]
    Unigene Representative Sequence: NM_020248
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377263(uc001aqk.1 uc001aql.1) ENST00000400904 ENST00000377258
    ENST00000377256 ENST00000537447

    miRNA
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    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate CTNNBIP1 (see all 61):
    hsa-miR-4291 hsa-miR-3194-5p hsa-miR-328 hsa-miR-188-5p hsa-miR-15a hsa-miR-25 hsa-miR-29a hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CTNNBIP1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CTNNBIP1 (see all 4)
    OriGene shRNA RFP: CTNNBIP1
    OriGene siRNA: CTNNBIP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CTNNBIP1
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CTNNBIP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CTNNBIP1

    Additional cDNA sequence: 

    AB021262.1 BC014300.1 BC146892.1 BC146896.1 

    12 DOTS entries:

    DT.446332  DT.101956912  DT.95196692  DT.91746023  DT.75103793  DT.95196641  DT.100684839  DT.100052211 
    DT.92044437  DT.95151207  DT.99973022  DT.97777665 

    24/244 AceView cDNA sequences (see all 244):

    AI284266 BQ024402 CR606136 BM021485 CD675305 BG676252 BC035794 BQ023951 
    BX097270 CD671708 BM052920 BM671879 BM722128 CN479209 CR625094 BM463223 
    BQ682197 BQ892669 Z43111 BQ879703 BU541435 BM710433 F13465 CB242070 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CTNNBIP1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                    -                                             
    SP2:                          -     -     -                           
    SP3:                                                                  
    SP4:              -     -     -     -     -                           


    ECgene alternative splicing isoforms for CTNNBIP1

    Expression
    for CTNNBIP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CTNNBIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGCGGAAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CTNNBIP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobulePeriportal HepatocytesLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CTNNBIP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CTNNBIP1

    SOURCE GeneReport for Unigene cluster: Hs.463759
        SABiosciences Expression via Pathway-Focused PCR Array including CTNNBIP1: 
              WNT Signaling Pathway in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTNNBIP1

    Orthologs
    for CTNNBIP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CTNNBIP1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ctnnbip11 , 5 catenin beta interacting protein 11, 5 93.83(n)1
    97.53(a)1    		   4 (79.66 cM)5
    670871  NM_001141930.11  NP_001135402.11 
     1495182365 
    chicken
    (Gallus gallus)    		 Aves CTNNBIP11 catenin, beta interacting protein 1 84.77(n)
    97.53(a)    		   771460  XM_001233909.2  XP_001233910.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CTNNBIP16
    		 --
    		 93(a)
    		 1 ↔ 1
    		 LGh(190227-229856)
    African clawed frog
    (Xenopus laevis)    		 Amphibia AB046868.12   -- 79.93(n)    AB046868.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii AB046866.12   -- 81.47(n)   58117  AB046866.1 


    ENSEMBL Gene Tree for CTNNBIP1 (if available)
    TreeFam Gene Tree for CTNNBIP1 (if available) 

    Paralogs
    for CTNNBIP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for CTNNBIP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/998 NCBI SNPs in CTNNBIP1 are shown (see all 998)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1871196161,2
    		--9907837(+) TTTCAC/GCTTCC 2 -- ds50010--------
    rs1914573211,2
    		--9907856(+) ACATAC/GAGCTA 2 -- ds50010--------
    rs12203961,2
    		C,F,A,H,--9908121(+) CCTTCT/CTAACG 2 -- ds500112Minor allele frequency- C:0.41NS EA NA WA CSA 785
    rs12203951,2
    		C,F,H,--9908269(+) GCCCAC/TGTGAT 2 -- ds500119Minor allele frequency- T:0.18NS EA NA WA CSA 2344
    rs1821724451,2
    		--9908332(+) ACACAA/CGAACC 2 -- ds50010--------
    rs1891234751,2
    		--9908456(+) TCATCA/GTTGTT 2 -- ut310--------
    rs151771,2
    		C,F,H,--9908482(+) GTGATC/TGTGAC 2 -- ut31 ese315Minor allele frequency- T:0.13EA NS WA 3382
    rs115555211,2
    		--9908496(+) GACAGC/GCTGGG 2 -- ut31 ese30--------
    rs9462731,2
    		C,F,H,--9908515(+) CACACG/ACTCAA 2 -- ut31 ese326Minor allele frequency- A:0.07NA EA MN NS WA CSA 2208
    rs143391,2
    		C,F,--9908588(+) GGCCTC/TGACAC 2 -- ut312Minor allele frequency- T:0.02MN WA 302

    HapMap Linkage Disequilibrium report for CTNNBIP1 (9908334 - 9970394 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CTNNBIP1: --

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    Disorders / Diseases
    for CTNNBIP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CTNNBIP1 for disorders           About GeneDecksing

    OMIM gene information: 607758    OMIM disorders: --

    20/25 diseases for CTNNBIP1 (see all 25):    About MalaCards
    actinic cheilitis    adenomatous polyposis coli    cheilitis    esophageal squamous cell carcinoma
    squamous cell carcinoma    desmoid tumor    acute lymphoblastic leukemia    lymphoblastic leukemia
    malignant glioma    wilms tumor    polyposis    endometrial carcinoma
    duodenitis    medulloblastoma    hepatocellular carcinoma    carcinoma
    laryngitis    esophagitis    gastric cancer    nasopharyngitis

    2 Novoseek disease relationships for CTNNBIP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 3.56 9 15492799 (2), 12417602 (1)
    cancer 0 3 15492799 (2), 12417602 (1)


    Export disorders for CTNNBIP1 gene to outside databases

    Publications
    for CTNNBIP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CTNNBIP1 gene, integrated from 9 sources (see all 73):
    (articles sorted by number of sources associating them with CTNNBIP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. (PubMed id 10898789)1, 2, 3, 9 Tago K.... Akiyama T. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. (PubMed id 12408825)1, 2 Daniels D.L. and Weis W.I. (2002)
    4. The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. (PubMed id 12408824)1, 2 Graham T.A.... Xu W. (2002)
    5. Mutation and expression of the beta-catenin-interacting protein ICAT in human colorectal tumors. (PubMed id 12417602)1, 9 Koyama T....Akiyama T. (2002)
    6. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    7. b-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesen chymal transition. (PubMed id 22081448)1 Giangreco A....Janes S.M. (2012)
    8. b-Catenin mutations in 2 nested stromal epithelial tum ors of the liver--a neoplasia with defective mesenchymal-epithelial transition. (PubMed id 22749188)1 Assmann G....Muller-Hocker J. (2012)
    9. R-Spondin potentiates Wnt/b-catenin signaling through orphan receptors LGR4 and LGR5. (PubMed id 22815884)1 Ruffner H....Cong F. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    External Searches for CTNNBIP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CTNNBIP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56998 HGNC: 16913 AceView: CTNNBIP1 Ensembl:ENSG00000178585 euGenes: HUgn56998
    ECgene: CTNNBIP1 Kegg: 56998 H-InvDB: CTNNBIP1

    Other Databases showing CTNNBIP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CTNNBIP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CTNNBIP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CTNNBIP1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for CTNNBIP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CTNNBIP1 gene:
    Search GeneIP for patents involving CTNNBIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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