Aliases for CTNNA3 Gene
External Ids for CTNNA3 Gene
Previous GeneCards Identifiers for CTNNA3 Gene
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
GeneCards Summary for CTNNA3 Gene
CTNNA3 (Catenin Alpha 3) is a Protein Coding gene. Diseases associated with CTNNA3 include arrhythmogenic right ventricular dysplasia, familial, 13 and familial isolated arrhythmogenic ventricular dysplasia, right dominant form. Among its related pathways are Adherens junction and Hypertrophic cardiomyopathy (HCM). GO annotations related to this gene include structural molecule activity and beta-catenin binding. An important paralog of this gene is CTNNA2.
UniProtKB/Swiss-Prot for CTNNA3 Gene
May be involved in formation of stretch-resistant cell-cell adhesion complexes.