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CTIF Gene

protein-coding   GIFtS: 45
GCID: GC18P046066

CBP80/20-Dependent Translation Initiation Factor

(Previous name: KIAA0427)
(Previous symbol: KIAA0427)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CBP80/20-Dependent Translation Initiation Factor1 2
KIAA04271 2 3 5
Gm6722

External Ids:    HGNC: 239251   Entrez Gene: 98112   Ensembl: ENSG000001340307   OMIM: 6131785   UniProtKB: O433103   

Export aliases for CTIF gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CTIF Gene:
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that
binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous
editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs
PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is
replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation
of the mRNAs resumes in the cytoplasm (Kim et al., 2009 (PubMed 19648179)).(supplied by OMIM, Dec 2009)

GeneCards Summary for CTIF Gene:
CTIF (CBP80/20-dependent translation initiation factor) is a protein-coding gene. GO annotations related to this gene include RNA binding. An important paralog of this gene is MIF4GD.

UniProtKB/Swiss-Prot: CTIF_HUMAN, O43310
Function: Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex
(CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its
interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome
via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is
replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the
pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated
mRNA decay (NMD)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CTIF
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCTIF promoter sequence
   Search Chromatin IP Primers for CTIF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CTIF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.1   Ensembl cytogenetic band:  18q21.1   HGNC cytogenetic band: 18q21.1

CTIF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTIF gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P046066:  view genomic region     (about GC identifiers)

Start:
46,065,417 bp from pter      End:
46,389,588 bp from pter
Size:
324,172 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CTIF_HUMAN, O43310 (See protein sequence)
Recommended Name: CBP80/20-dependent translation initiation factor  
Size: 598 amino acids; 67587 Da
Subunit: Interacts with NCBP1/CBP80; the interaction is direct. Associates with the eukaryotic translation
initiation factor 3 (eIF-3) complex
Sequence caution: Sequence=BAA24857.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAG53180.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: B3KTR8 Q8IVD5
Alternative splicing: 2 isoforms:  O43310-1   O43310-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CTIF: NX_O43310

Explore proteomics data for CTIF at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CTIF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001135869.1  NP_055587.1  

    ENSEMBL proteins: 
     ENSP00000256413   ENSP00000372459   ENSP00000467965   ENSP00000467425   ENSP00000465405  
     ENSP00000467957  

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    Novus Biologicals CTIF Protein
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    Cloud-Clone Corp. Proteins for CTIF

     
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    Search eBioscience for ELISAs for CTIF 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR003890 MIF4G-like_typ-3
     IPR016021 MIF4-like_typ_1/2/3
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry O43310

    ProtoNet protein and cluster: O43310

    1 Blocks protein domain: IPB003890 Initiation factor eIF-4 gamma

    UniProtKB/Swiss-Prot: CTIF_HUMAN, O43310
    Similarity: Belongs to the CTIF family
    Similarity: Contains 1 MIF4G domain


    Find genes that share domains with CTIF           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CTIF_HUMAN, O43310
    Function: Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex
    (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its
    interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome
    via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is
    replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the
    pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated
    mRNA decay (NMD)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0005488binding ----
    GO:0005515protein binding IPI19648179
         
    Find genes that share ontologies with CTIF           About GenesLikeMe


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target CTIF:
    hsa-mir-877-3p (MIRT037103)

    Block miRNA regulation of human, mouse, rat CTIF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CTIF (see all 91):
    hsa-miR-193a-3p hsa-miR-15a hsa-miR-4275 hsa-miR-629* hsa-miR-298 hsa-miR-637 hsa-miR-149 hsa-miR-3909
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat CTIF

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    GenScript: all cDNA clones in your preferred vector (see all 2): CTIF (NM_014772)
    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CTIF_HUMAN, O43310: Cytoplasm, perinuclear region

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0048471perinuclear region of cytoplasm IDA19648179

    Find genes that share ontologies with CTIF           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CTIF
    Interactions:

        Search GeneGlobe Interaction Network for CTIF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for CTIF (ENSP000003724594) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NR1D1ENSP000002466724STRING: ENSP00000246672
    NR1D2ENSP000003100064STRING: ENSP00000310006
    RARAENSP000002540664STRING: ENSP00000254066
    RARBENSP000003322964STRING: ENSP00000332296
    RARGENSP000003326954STRING: ENSP00000332695
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP19648179
    GO:0006446regulation of translational initiation IMP19648179

    Find genes that share ontologies with CTIF           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CTIF



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CTIF gene (2 alternative transcripts): 
    NM_001142397.1  NM_014772.2  

    Unigene Cluster for CTIF:

    CBP80/20-dependent translation initiation factor
    Hs.145230  [show with all ESTs]
    Unigene Representative Sequence: NM_001142397
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000256413(uc002ldc.3 uc002lde.4) ENST00000382998(uc002ldd.3)
    ENST00000591412 ENST00000591387 ENST00000587752 ENST00000588345 ENST00000589585
    ENST00000587769 ENST00000587860 ENST00000592658 ENST00000590422
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CTIF (see all 91):
    hsa-miR-193a-3p hsa-miR-15a hsa-miR-4275 hsa-miR-629* hsa-miR-298 hsa-miR-637 hsa-miR-149 hsa-miR-3909
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    Additional mRNA sequence: 

    AB007887.1 AK095970.1 BC042146.1 

    6 DOTS entries:

    DT.444649  DT.100817030  DT.100817032  DT.40197646  DT.121103640  DT.95272817 

    Selected AceView cDNA sequences (see all 127):

    CD360061 BQ717566 AB007887 BU688371 BQ940711 NM_014772 BM727339 BM695665 
    BC042146 BQ052055 AA364764 BU192650 CN484944 BQ054220 AW205899 CD723256 
    C00833 CA433069 BQ888225 T17404 CD644662 AI885414 CB163904 AL134283 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CTIF    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10
    SP1:                                                                              
    SP2:                                                                              
    SP3:                                                                              
    SP4:                                                                              
    SP5:                                                                              


    ECgene alternative splicing isoforms for CTIF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CTIF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGTGCCCCA
    CTIF Expression
    About this image

    CTIF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CTIF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.145230

    UniProtKB/Swiss-Prot: CTIF_HUMAN, O43310
    Tissue specificity: Widely expressed

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CTIF gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ctif1 , 5 CBP80/20-dependent translation initiation factor1, 5 89.06(n)1
    93.5(a)1
      18 (51.06 cM)5
    2690371  NM_201354.21  NP_958742.21 
     754312245 
    chicken
    (Gallus gallus)
    Aves CTIF1 CBP80/20-dependent translation initiation factor 81.53(n)
    87.31(a)
      770140  XM_003642898.2  XP_003642946.1 
    lizard
    (Anolis carolinensis)
    Reptilia CTIF6
    CBP80/20-dependent translation initiation factor
    78(a)
    1 ↔ 1
    2(626324-788267)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.150602 Xenopus laevis transcribed sequence with weak similarity more 82.76(n)    BJ090706.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ctif1 CBP80/20-dependent translation initiation factor 69.58(n)
    69.23(a)
      100537309  XM_003200812.2  XP_003200860.2 


    ENSEMBL Gene Tree for CTIF (if available)
    TreeFam Gene Tree for CTIF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CTIF gene
    MIF4GD2  

    Find genes that share paralogs with CTIF           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CTIF (see all 6933)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0357494
    A breast cancer sample4--see VAR_0357492 V L mis40--------
    VAR_0357504
    A breast cancer sample4--see VAR_0357502 M I mis40--------
    rs1876959991,2
    --46063497(+) CCAACA/GGGAAG 2 -- us2k10--------
    rs72358721,2
    C,F--46063727(+) CTGTTT/CTGTGT 2 -- us2k111Minor allele frequency- C:0.07NA WA CSA EA 372
    rs1913806561,2
    --46063742(+) AGCCCA/GGGAGA 2 -- us2k10--------
    rs1488910661,2
    --46063855(+) TTGCCC/TAGGCT 2 -- us2k10--------
    rs1838648091,2
    --46063951(+) TTGTAA/CCCTTT 2 -- us2k10--------
    rs1869389691,2
    --46063976(+) GCTTAA/TCCTTT 2 -- us2k10--------
    rs1917868891,2
    --46064018(+) TTGCCA/GGGCAC 2 -- us2k10--------
    rs1441030561,2
    C--46064031(+) TGGCTC/GAAGCC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CTIF (46065417 - 46315417 bp, first 250kb of CTIF)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CTIF (see all 41):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2717064CNV Deletion23290073
    esv2668418CNV Deletion23128226
    esv2717063CNV Deletion23290073
    esv5388CNV Deletion18987735
    esv2717069CNV Deletion23290073
    esv2253454CNV Deletion18987734
    esv1006969CNV Deletion20482838
    dgv495e201CNV Deletion23290073
    esv1745659CNV Deletion17803354
    esv2717070CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CTIF
    DNA2.0 Custom Variant and Variant Library Synthesis for CTIF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613178    OMIM disorders: --


    Find genes that share disorders with CTIF           About GenesLikeMe


    Export disorders for CTIF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CTIF gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with CTIF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A new MIF4G domain-containing protein, CTIF, directs nuclear cap- binding protein CBP80/20-dependent translation. (PubMed id 19648179)1, 2, 3 Kim K.M....Kim Y.K. (Genes Dev. 2009)
    2. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    6. Genome-wide meta-analysis identifies new susceptibility loci for migraine. (PubMed id 23793025)1 Anttila V.... . (Nat. Genet. 2013)
    7. Gene network analysis in a pediatric cohort identifies novel lung function genes. (PubMed id 24023788)1 Ong B.A....Hakonarson H. (PLoS ONE 2013)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2. (PubMed id 21840310)1 Choe J....Kim Y.K. (FEBS Lett. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9811 HGNC: 23925 AceView: KIAA0427 Ensembl:ENSG00000134030 euGenes: HUgn9811
    ECgene: CTIF H-InvDB: CTIF

    (According to HUGE)
    About This Section

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    HUGE: KIAA0427

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CTIF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CTIF gene:
    Search GeneIP for patents involving CTIF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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