External Ids for CTF1 Gene
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
GeneCards Summary for CTF1 Gene
CTF1 (Cardiotrophin 1) is a Protein Coding gene. Diseases associated with CTF1 include neonatal stroke and acute myocardial infarction. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and NFAT and Cardiac Hypertrophy. GO annotations related to this gene include cytokine activity and leukemia inhibitory factor receptor binding.
UniProtKB/Swiss-Prot for CTF1 Gene
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor