CTDSPL Gene
protein-coding GIFtS: 57
GCID: GC03P037878
|
|
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide...(Previous name: chromosome 3 open reading frame 8 )
(Previous symbol: C3orf8)
| |
Aliases
for CTDSPL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) SmallPhosphatase-Like1 2 | | NLI-Interacting Factor 12 3 | | C3orf81 2 3 | | EC 3.1.3.163 8 | | RBSP31 2 3 | | Chromosome 3 Open Reading Frame 81 | | SCP31 2 3 | | CTD Small Phosphatase-Like Protein2 | | HYA221 2 | | RB Protein Serine Phosphatase From Chromosome 32 | | PSR11 2 | | NIF13 | | Carboxy-Terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 32 3 | | NIFL3 | | Nuclear LIM Interactor-Interacting Factor 12 3 | | YA223 | | Small C-Terminal Domain Phosphatase 32 3 | | HYA221 2 | | Small CTD Phosphatase 32 3 | | Protein YA223 | | CTDSP-Like1 | | EC 3.1.38 | | NIF-Like Protein2 3 | | |
Export aliases for CTDSPL gene to outside databasesPrevious GC identifer: GC03P037863 |
Summaries
for CTDSPL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CTDSL_HUMAN, O15194Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation (Bysimilarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing innon-neuronal cells
Gene Wiki entry for CTDSPL
|
Genomic Views
for CTDSPL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CTDSPL gene promoter:
RP58 HTF Pax-2 Pax-2a Meis-1b Pax-2b FOXO4 c-Myb Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CTDSPL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTDSPL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.3 Ensembl cytogenetic band: 3p22.2 HGNC cytogenetic band: 3p21.3CTDSPL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P037878: view genomic region
(about GC identifiers)
Start:
|
37,903,451 bp from pter |
End:
|
38,025,960 bp from pter |
Size:
|
122,510 bases |
Orientation:
|
plus strand |
|
Proteins
for CTDSPL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CTDSL_HUMAN, O15194 (See
protein sequence)Recommended Name: CTD small phosphatase-like protein Size: 276 amino acids; 31129 Da
Cofactor: Binds 1 magnesium ion per monomer (By similarity)
Subunit: Monomer. Interacts with REST
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=BAA21667.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for CTDSPL:2HHL (3D)
Secondary accessions: Q3ZTU0 Q70KI4 Q7Z5Q2Alternative splicing: 2 isoforms: O15194-1 O15194-2 Explore the universe of human proteins at neXtProt for CTDSPL: NX_O15194
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15194
4/9 DME Specific Peptides for CTDSPL (O15194) (see all 9)
CTDSPL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001008393.1 NP_005799.2
ENSEMBL proteins: ENSP00000398288 ENSP00000273179 ENSP00000408183 ENSP00000404977 ENSP00000407443 ENSP00000409600
Human Recombinant Protein Products for CTDSPL:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CTDSPL for ontologies About GeneDecksing
CTDSPL Antibody Products:
Assay Products for CTDSPL: |
Protein
Domains /
Families
for CTDSPL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CTDSPL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15194ProtoNet protein and cluster: O15194 1 Blocks protein family: IPB004274 NLI interacting factor
UniProtKB/Swiss-Prot: CTDSL_HUMAN, O15194Similarity: Contains 1 FCP1 homology domain |
Function
for CTDSPL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CTDSL_HUMAN, O15194Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation (Bysimilarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing innon-neuronal cellsCatalytic activity: A phosphoprotein + H(2)O = a protein + phosphate Enzyme Numbers (IUBMB): EC 3.1.3.161 2 EC 3.1.32
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CTDSPL for ontologies About GeneDecksing
Phenotypes:
5 GenomeRNAi human phenotypes for CTDSPL:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CTDSPL (NM_005808) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CTDSPL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTDSPL |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTDSPL |
|
Pathways & Interactions
for CTDSPL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of cytoplasmic and nuclear SMAD2/3 signaling | | | 2 | Signaling by BMP | |
2  BioSystems Pathways for CTDSPL
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTDSPL
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for CTDSPL (O151943 ENSP000002731794) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
CTDSPL for ontologies About GeneDecksing
|
Drugs & Compounds
for CTDSPL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CTDSPL for compounds About GeneDecksing
 Browse Tocris compounds for CTDSPL
1 Novoseek chemical compound relationship for CTDSPL gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| atp |
9.91 |
1 |
9560416 (1) |
Search CenterWatch for drugs/clinical trials and news about CTDSPL / CTDSL
|
Transcripts
for CTDSPL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CTDSPL gene (2 alternative transcripts): NM_001008392.1 NM_005808.2 Unigene Cluster for CTDSPL: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like Hs.475963 [show with all ESTs]Unigene Representative Sequence: D881538 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000443503(uc003chh.3) ENST00000273179(uc003chg.3) ENST00000435525
ENST00000486978 ENST00000310189 ENST00000416688 ENST00000447745 ENST00000436654
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CTDSPL (NM_005808) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CTDSPL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTDSPL |
Additional cDNA sequence: AJ575644.1 AJ575645.1 AY279532.1 AY364238.1 D88153.1 13 DOTS entries: DT.40111211 DT.100795972 DT.95209056 DT.454957 DT.95209068 DT.95209057 DT.95209049 DT.100795971 DT.87078915 DT.91773812 DT.120860716 DT.95336707 DT.120860867 24/357 AceView cDNA sequences (see all 357): AI971825 AW297534 AI014464 AA421118 BQ026609 AI768308 Z44840 AA664401 BM478840 BP340299 AI800219 BU689808 BI712061 AI401817 BQ425314 AY279532 AI352325 BM449987 AA703367 BQ181940 BM746160 BI912471 AW275051 AI760260
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CTDSPL (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CTDSPL
|
Expression
for CTDSPL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CTDSPL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAAACTGCA
About this image
See CTDSPL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CTDSPL
SOURCE GeneReport for Unigene cluster: Hs.475963
UniProtKB/Swiss-Prot: CTDSL_HUMAN, O15194Tissue specificity: Expression is restricted to non-neuronal tissues
SABiosciences Custom PCR Arrays for CTDSPL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CTDSPL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CTDSPL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CTDSPL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CTDSPL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTDSPL |
Orthologs
for CTDSPL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for CTDSPL gene from 7/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CTDSPL1 |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide more |
81.7(n)
89.09(a) |
|
408252 NM_001001316.1 NP_001001316.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CTDSPL6 |
-- |
89(a) |
1 ↔ 1 |
6(1195264-1218650) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.189312 |
Xenopus laevis NIF (NIF) mRNA, complete cds |
81.32(n) |
|
AY280863.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
CK361160.12 |
-- |
78.76(n) |
|
CK361160.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG58306 |
-- |
46(a) |
1 → many |
3L(15985753-15997836) |
worm
(Caenorhabditis elegans) |
Secernentea |
scpl-16 |
SCP(Small C-terminal domain Phosphatase)-Like phos... |
28(a) |
possible ortholog |
I(10086381-10102001) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
PSR11 |
Psr1p |
52.99(n)
57.8(a) |
|
850650 NP_013091.1 |
ENSEMBL Gene Tree for CTDSPL (if available)
TreeFam Gene Tree for CTDSPL (if available) |
Paralogs
for CTDSPL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CTDSPL gene
- CTDSPL22 CTDSP12 CTDSP22
3 SIMAP similar genes for CTDSPL using alignment to 5 protein entries: CTDSL_HUMAN (see all proteins):CTDSP2 CTDSP1 CTDNEP1
CTDSPL for paralogs About GeneDecksing
|
Genomic Variants
for CTDSPL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CTDSPL (37903451 - 38025960 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 13 variations for CTDSPL
12 CNVs: 7408 53930 37912 32489 51094 79741 79740 63445 1365 31102 3425 91276
1 Indel: 10736 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CTDSPL |
|
Disorders
/ Diseases
for CTDSPL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CTDSPL for disorders About GeneDecksing
OMIM gene information: 608592
OMIM disorders: --
14  diseases for CTDSPL: About MalaCardsrenal cell carcinoma pandas azoospermia lung carcinoma
breast carcinoma lung cancer carcinoma prostate cancer
breast cancer sarcoma cervicitis prostatitis
immunodeficiency neuronitis
Human Genome Epidemiology (HuGE) Navigator: CTDSPL (3 documents)
Export disorders for CTDSPL gene to outside databases
|
Publications
for CTDSPL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CTDSPL gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with CTDSPL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line. (PubMed id 9179494)1, 2, 3 Ishikawa S.... Nakamura Y. (1997)
- An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies. (PubMed id 12543795)1, 3, 9 Protopopov A.... Zabarovsky E.R. (2003)
- RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies. (PubMed id 15051889)1, 2 Kashuba V.I....Zabarovsky E.R. (2004)
- A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5. (PubMed id 12721286)1, 2 Yeo M....Gill G.N. (2003)
- High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer. (PubMed id 19478941)1, 9 Kashuba V.I....Zabarovsky E.R. (2009)
- MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. (PubMed id 21643017)1 Zheng Y.S....Chen Y.Q. (2012)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Simultaneous down-regulation of tumor suppressor gene s RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer. (PubMed id 20193080)1 Senchenko V.N....Zabarovsky E.R. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- RBSP3 is frequently altered in premalignant cervical lesions: clinical and prognostic significance. (PubMed id 19885927)1 Mitra S....Panda C.K. (2010)
|
External Searches for CTDSPL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CTDSPL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CTDSPL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CTDSPL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CTDSPL gene:
Search GeneIP for patents involving CTDSPL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CTDSPL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CTDSPL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CTDSPL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CTDSPL | | | OriGene Protein Over-expression Lysate for CTDSPL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CTDSPL | | OriGene 3'-UTR Clone for CTDSPL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CTDSPL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CTDSPL | | OriGene Custom Protein Services for CTDSPL | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CTDSPL | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CTDSPL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTDSPL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CTDSPL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CTDSPL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CTDSPL |
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| | | | Search Tocris compounds for CTDSPL |
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 | | | CTDSPL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTDSPL |
|  |  |  |  | | | | ThermoFisher Antibodies for CTDSPL |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTDSPL |
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