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Aliases for CTDP1 Gene

Aliases for CTDP1 Gene

  • CTD Phosphatase Subunit 1 2 3 5
  • CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 2 3
  • FCP1 3 4
  • RNA Polymerase II Subunit A C-Terminal Domain Phosphatase 3
  • Transcription Factor IIF-Associating CTD Phosphatase 1 3
  • CTD Of POLR2A, Phosphatase Of, Subunit 1 3
  • TFIIF-Associating CTD Phosphatase 1 3
  • TFIIF-Associating CTD Phosphatase 4
  • Serine Phosphatase FCP1a 3
  • EC 4
  • CCFDN 3

External Ids for CTDP1 Gene

Previous GeneCards Identifiers for CTDP1 Gene

  • GC18P076954
  • GC18P077494
  • GC18P077174
  • GC18P075538
  • GC18P075540
  • GC18P074064

Summaries for CTDP1 Gene

Entrez Gene Summary for CTDP1 Gene

  • This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

GeneCards Summary for CTDP1 Gene

CTDP1 (CTD Phosphatase Subunit 1) is a Protein Coding gene. Diseases associated with CTDP1 include Congenital Cataracts, Facial Dysmorphism, And Neuropathy and Neuropathy, Hereditary Motor And Sensory, Russe Type. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and HIV Life Cycle. GO annotations related to this gene include phosphoprotein phosphatase activity and CTD phosphatase activity.

UniProtKB/Swiss-Prot for CTDP1 Gene

  • Processively dephosphorylates Ser-2 and Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.

Gene Wiki entry for CTDP1 Gene

Additional gene information for CTDP1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTDP1 Gene

Genomics for CTDP1 Gene

Regulatory Elements for CTDP1 Gene

Enhancers for CTDP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18H079677 1.4 ENCODE dbSUPER 44.7 +0.1 99 4.8 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 CTDP1 ENSG00000266901 ENSG00000265101 ENSG00000266273 ENSG00000266586 ATP9B LOC105376875
GH18H079682 1 FANTOM5 ENCODE 58.4 +3.2 3246 0.3 CTCF MAX GABPA POLR2A EED IKZF1 MLLT1 ATF7 RUNX3 MYC CTDP1 PQLC1 NFATC1 ADNP2 LOC105376875 ENSG00000266901
GH18H079397 1.8 FANTOM5 Ensembl ENCODE dbSUPER 7.2 -277.3 -277281 9.7 HDGF PKNOX1 RB1 SIN3A BATF GLIS2 ATF7 ETV6 RUNX3 CREM NFATC1 ATP9B ADNP2 RBFA PARD6G CTDP1 ENSG00000267287 KCNG2 ENSG00000279637
GH18H079624 1.4 FANTOM5 Ensembl ENCODE 7.5 -54.6 -54639 1.7 PKNOX1 ATF1 MAX RELA POLR2A FOXK2 EED PRDM10 ETV6 ATF7 CTDP1 ENSG00000267287 PQLC1 TXNL4A NFATC1 ADNP2 PIR59230 ENSG00000274828
GH18H079686 0.4 ENCODE 24.7 +4.6 4592 0.4 RUNX3 CTDP1 LOC105376875 ENSG00000266901
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CTDP1 on UCSC Golden Path with GeneCards custom track

Promoters for CTDP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for CTDP1 Gene

Genomic Locations for CTDP1 Gene
76,823 bases
Plus strand

Genomic View for CTDP1 Gene

Genes around CTDP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTDP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTDP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTDP1 Gene

Proteins for CTDP1 Gene

  • Protein details for CTDP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA polymerase II subunit A C-terminal domain phosphatase
    Protein Accession:
    Secondary Accessions:
    • A8MY97
    • Q7Z644
    • Q96BZ1
    • Q9Y6F5

    Protein attributes for CTDP1 Gene

    961 amino acids
    Molecular mass:
    104399 Da
    Quaternary structure:
    • Homodimer. Interacts with GTF2F1. Interacts with WDR77, SNRPB and SNRNP70.
    • Sequence=AAC64549.1; Type=Miscellaneous discrepancy; Note=Cloning artifact.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CTDP1 Gene

    Alternative splice isoforms for CTDP1 Gene


neXtProt entry for CTDP1 Gene

Post-translational modifications for CTDP1 Gene

  • Phosphorylated. In the presence of TFIIF, the phosphorylated form has an increased CTD phosphatase activity. The phosphorylation is required for the physical interaction with GTF2F1.
  • Ubiquitination at isoforms=4653
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CTDP1 Gene

Domains & Families for CTDP1 Gene

Gene Families for CTDP1 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Protein Domains for CTDP1 Gene

Suggested Antigen Peptide Sequences for CTDP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CTDP1: view

No data available for UniProtKB/Swiss-Prot for CTDP1 Gene

Function for CTDP1 Gene

Molecular function for CTDP1 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
UniProtKB/Swiss-Prot Function:
Processively dephosphorylates Ser-2 and Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.

Enzyme Numbers (IUBMB) for CTDP1 Gene

Phenotypes From GWAS Catalog for CTDP1 Gene

Gene Ontology (GO) - Molecular Function for CTDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001096 TFIIF-class transcription factor binding IPI 12732728
GO:0004721 phosphoprotein phosphatase activity IEA,TAS --
GO:0005515 protein binding IPI 9765293
GO:0008420 CTD phosphatase activity IDA 9765293
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with CTDP1: view
genes like me logo Genes that share phenotypes with CTDP1: view

Human Phenotype Ontology for CTDP1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

miRNA for CTDP1 Gene

Clone Products

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for CTDP1 Gene

Localization for CTDP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTDP1 Gene

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CTDP1 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (3)
  • Actin filaments (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CTDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IDA 22692537
GO:0005634 nucleus IDA,IEA 15723517
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IEA --
GO:0005813 centrosome IDA 22692537
genes like me logo Genes that share ontologies with CTDP1: view

Pathways & Interactions for CTDP1 Gene

genes like me logo Genes that share pathways with CTDP1: view

Gene Ontology (GO) - Biological Process for CTDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006366 transcription from RNA polymerase II promoter TAS --
GO:0006368 transcription elongation from RNA polymerase II promoter TAS --
GO:0006470 protein dephosphorylation IDA,IEA 9765293
GO:0007049 cell cycle IEA --
GO:0010458 exit from mitosis IMP 22692537
genes like me logo Genes that share ontologies with CTDP1: view

No data available for SIGNOR curated interactions for CTDP1 Gene

Drugs & Compounds for CTDP1 Gene

(5) Drugs for CTDP1 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
calcium Nutra 0

(1) Additional Compounds for CTDP1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • NFB Orthophosphate
  • O-Phosphoric acid
  • Ortho-phosphate
  • Orthophosphate (PO43-)
  • Orthophosphate(3-)
genes like me logo Genes that share compounds with CTDP1: view

Transcripts for CTDP1 Gene

Unigene Clusters for CTDP1 Gene

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CTDP1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b · 14c · 14d
SP3: - - -
SP4: -
SP5: -
SP7: - - - -
SP8: - - -

Relevant External Links for CTDP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CTDP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CTDP1 Gene

mRNA differential expression in normal tissues according to GTEx for CTDP1 Gene

This gene is overexpressed in Whole Blood (x5.7).

Protein differential expression in normal tissues from HIPED for CTDP1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (24.0), Plasma (13.0), and Lymph node (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CTDP1 Gene

Protein tissue co-expression partners for CTDP1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CTDP1 Gene:


SOURCE GeneReport for Unigene cluster for CTDP1 Gene:


mRNA Expression by UniProt/SwissProt for CTDP1 Gene:

Tissue specificity: Ubiquitously expressed.

Evidence on tissue expression from TISSUES for CTDP1 Gene

  • Intestine(4.1)
  • Liver(4.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CTDP1 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Head and neck:
  • brain
  • cerebellum
  • cheek
  • chin
  • cranial nerve
  • eye
  • eyelid
  • face
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • pituitary gland
  • skull
  • tooth
  • breast
  • chest wall
  • clavicle
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
  • adrenal gland
  • kidney
  • liver
  • ovary
  • pelvis
  • penis
  • prostate
  • testicle
  • uterus
  • vagina
  • vulva
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • vertebrae
genes like me logo Genes that share expression patterns with CTDP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for CTDP1 Gene

Orthologs for CTDP1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CTDP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CTDP1 33 34
  • 98.75 (n)
(Canis familiaris)
Mammalia CTDP1 33 34
  • 79.81 (n)
(Rattus norvegicus)
Mammalia Ctdp1 33
  • 78.9 (n)
(Mus musculus)
Mammalia Ctdp1 33 16 34
  • 78.66 (n)
(Bos Taurus)
Mammalia CTDP1 33
  • 78.22 (n)
(Monodelphis domestica)
Mammalia CTDP1 34
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia CTDP1 34
  • 68 (a)
(Gallus gallus)
Aves CTDP1 33 34
  • 66.47 (n)
(Anolis carolinensis)
Reptilia CTDP1 34
  • 64 (a)
(Danio rerio)
Actinopterygii ctdp1 33 34
  • 63.53 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG12252 35
  • 35 (a)
Fcp1 34
  • 29 (a)
(Caenorhabditis elegans)
Secernentea F36F2.6 35
  • 39 (a)
fcp-1 34
  • 30 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FCP1 34 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.467 34
  • 45 (a)
Species where no ortholog for CTDP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for CTDP1 Gene

Gene Tree for CTDP1 (if available)
Gene Tree for CTDP1 (if available)

Paralogs for CTDP1 Gene

No data available for Paralogs for CTDP1 Gene

Variants for CTDP1 Gene

Sequence variations from dbSNP and Humsavar for CTDP1 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs113994102 Pathogenic 79,710,825(+) ACAGG(C/T)ATGAG intron-variant
rs146831211 Uncertain significance 79,704,814(+) CACAC(A/G)CGCCT reference, synonymous-codon
rs777623040 Uncertain significance 79,715,421(+) GAAGA(C/T)GCGGG reference, missense
rs11549119 Benign 79,715,455(+) GGAGC(A/G/T)AAGAT reference, synonymous-codon
rs17855830 Benign 79,680,128(+) AGTCC(G/T)CCGGG upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CTDP1 Gene

Variant ID Type Subtype PubMed ID
nsv954102 CNV deletion 24416366
nsv953928 CNV deletion 24416366
nsv828346 CNV gain 20364138
nsv577909 CNV loss 21841781
nsv525694 CNV loss 19592680
nsv519406 CNV gain 19592680
nsv509709 CNV insertion 20534489
nsv477644 CNV novel sequence insertion 20440878
nsv470437 CNV loss 18288195
nsv458316 CNV loss 19166990
nsv428359 CNV gain 18775914
nsv2382 CNV deletion 18451855
nsv1146834 CNV deletion 26484159
nsv1143890 CNV deletion 24896259
nsv1138641 CNV deletion 24896259
nsv1135064 CNV deletion 24896259
nsv1132883 CNV insertion 24896259
nsv1130380 CNV deletion 24896259
nsv1118795 CNV deletion 24896259
nsv1072825 CNV deletion 25765185
nsv1072284 CNV deletion 25765185
nsv1066888 CNV gain 25217958
nsv1065902 CNV gain 25217958
nsv1064506 CNV gain 25217958
nsv1061450 CNV gain 25217958
esv996423 CNV deletion 20482838
esv988016 CNV deletion 20482838
esv8210 CNV loss 19470904
esv3643316 CNV loss 21293372
esv3643315 CNV gain 21293372
esv3643314 CNV loss 21293372
esv3643313 CNV gain 21293372
esv3643312 CNV loss 21293372
esv3583194 CNV loss 25503493
esv3397129 CNV duplication 20981092
esv3377806 CNV duplication 20981092
esv3310462 CNV novel sequence insertion 20981092
esv3107123 CNV deletion 24192839
esv2926 CNV loss 18987735
esv28962 CNV loss 19812545
esv2741776 CNV deletion 23290073
esv2717689 CNV deletion 23290073
esv2717688 CNV deletion 23290073
esv2717687 CNV deletion 23290073
esv2717686 CNV deletion 23290073
esv2717685 CNV deletion 23290073
esv2717683 CNV deletion 23290073
esv2717682 CNV deletion 23290073
esv2717681 CNV deletion 23290073
esv2717680 CNV deletion 23290073
esv2717679 CNV deletion 23290073
esv2671018 CNV deletion 23128226
esv2656662 CNV deletion 23128226
esv25884 CNV loss 19812545
esv2564978 CNV deletion 19546169
esv2531346 CNV insertion 19546169
esv2447548 CNV deletion 19546169
esv2134672 CNV deletion 18987734
esv1626049 CNV deletion 17803354
esv1394695 CNV deletion 17803354
esv1368125 CNV insertion 17803354
esv1046194 CNV insertion 17803354
esv1011198 CNV insertion 20482838
esv1003318 CNV deletion 20482838
dgv6118n54 CNV loss 21841781
dgv6117n54 CNV loss 21841781
dgv212e215 CNV deletion 23714750
dgv1661n106 CNV deletion 24896259

Variation tolerance for CTDP1 Gene

Residual Variation Intolerance Score: 33.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.07; 75.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CTDP1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CTDP1 Gene

Disorders for CTDP1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for CTDP1 Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
congenital cataracts, facial dysmorphism, and neuropathy
  • ccfdn
neuropathy, hereditary motor and sensory, russe type
  • charcot-marie-tooth disease type 4g
charcot-marie-tooth disease, type 4d
  • charcot-marie-tooth disease type 4d
  • peripheral neuropathy
  • aids, slow progression to
- elite association - COSMIC cancer census association via MalaCards
Search CTDP1 in MalaCards View complete list of genes associated with diseases


  • Congenital cataracts, facial dysmorphism, and neuropathy (CCFDN) [MIM:604168]: An autosomal recessive developmental disorder characterized by a complex clinical phenotype with seemingly unrelated features involving multiple organs and systems. Developmental abnormalities include congenital cataracts and microcorneae, hypomyelination of the peripheral nervous system, impaired physical growth, delayed early motor and intellectual development, facial dysmorphism and hypogonadism. Central nervous system involvement, with cerebral and spinal cord atrophy, may be the result of disrupted development with superimposed degenerative changes. Affected individuals are prone to severe rhabdomyolysis after viral infections and to serious complications related to general anesthesia (such as pulmonary edema and epileptic seizures). {ECO:0000269 PubMed:14517542}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for CTDP1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CTDP1: view

No data available for Genatlas for CTDP1 Gene

Publications for CTDP1 Gene

  1. The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP. (PMID: 12560496) Licciardo P … Majello B (Nucleic acids research 2003) 3 4 22 60
  2. The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation. (PMID: 12591939) Friedl EM … Reinberg D (Proceedings of the National Academy of Sciences of the United States of America 2003) 3 4 22 60
  3. Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF. (PMID: 12591941) Kamada K … Burley SK (Proceedings of the National Academy of Sciences of the United States of America 2003) 3 4 22 60
  4. FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO. (PMID: 9765293) Archambault J … Greenblatt J (The Journal of biological chemistry 1998) 2 3 4 60
  5. Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit. (PMID: 22692537) Visconti R … Grieco D (Nature communications 2012) 3 4 60

Products for CTDP1 Gene

Sources for CTDP1 Gene

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