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CTCFL Gene

protein-coding GIFtS: 51

GC20M055505

CCCTC-binding factor (zinc finger protein)-like
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BORIS ^¹, ², ³, ⁵
CT27 ^¹, ², ³
CTCF-T ^²
MGC163358 ^²
OTTHUMP00000174287 ^²
dJ579F20.2 ^¹, ²

Descriptions
BORIS-like protein ^²
Brother of the regulator of imprinted sites ^², ³
CCCTC-binding factor ^³
CCCTC-binding factor (zinc finger protein)-like ^²
CCCTC-binding factor-like protein ^²
CTCF paralog ^³
CTCF-like protein ^³
Cancer/testis antigen 27 ^², ³
Zinc finger protein CTCF-T ^³

External Ids
HGNC: 16234¹
Entrez Gene: 140690²
UniProtKB: Q8NI51³
Ensembl: ENSG00000124092⁷

Search outside databases for aliases for CTCFL gene

Previous GC identifers: GC20M055800 GC20M056710 GC20M056757

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CTCFL:

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes

different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive

insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to

be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily

in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed

in a mutually exclusive pattern that correlates with resetting of methylation marks during male

germ cell differentiation. [provided by RefSeq]

UniProtKB/Swiss-Prot: CTCFL_HUMAN, Q8NI51

Function: Testis-specific DNA binding protein responsible for insulator function, nuclear

architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin

modifiers. Plays a key role in gene imprinting in male germline, by participating in the

establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly

binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate

histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases

at these sites (By similarity). Seems to act as tumor suppressor

Gene Wiki entry for CTCFL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CTCFL gene

Entrez Gene cytogenetic band: 20q13.31 Ensembl cytogenetic band: 20q13.31 HGNC cytogenetic band: 20q13.31

CTCFL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M055505: (about GC identifiers)

Start:	55,505,630 bp from pter
End:	55,534,041 bp from pter
Size:	28,412 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000020.9 NT_011362.9

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CTCFL_HUMAN, Q8NI51 (See protein sequence)

Recommended Name: Transcriptional repressor CTCFL

Size: 663 amino acids; 75717 Da

Subunit: Interacts with histones and PRMT7

Subcellular location: Cytoplasm. Nucleus

Developmental stage: Is up-regulated in primary spermatocytes (expression overlapping with the

genome-wide erasure of methylation) to become silenced on activation of CTCF in post-meiotic

germline cells (expression corresponding to DNA remethylation)

Secondary accessions: Q5JUG4 Q9BZ30 Q9NQJ3

REFSEQ proteins: NP_542185.2

ENSEMBL proteins:

ENSP00000360239 ENSP00000243914

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (BORIS)
	Human Recombinant Proteins from Abnova (CTCFL)

OriGene Purified Recombinant Human Protein: CTCFL

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for CTCFL:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for CTCFL
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (BORIS), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibody for CTCFL

Assays for CTCFL:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8NI51

ProtoNet protein and cluster: Q8NI51

UniProtKB/Swiss-Prot: CTCFL_HUMAN, Q8NI51

Similarity: Belongs to the CTCF zinc-finger protein family

Similarity: Contains 11 C2H2-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CTCFL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CTCFL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_080618

Applied Biosystems Silencer® siRNAs for CTCFL

Sigma-Aldrich siRNA for CTCFL

Sigma-Aldrich shRNA for CTCFL

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_080618
Myc/DDK tagged cDNA clone in CMV expression vector: NM_080618
untagged cDNA clones in CMV expression vector (see all 3): NM_080618

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_080618

UniProtKB/Swiss-Prot: CTCFL_HUMAN, Q8NI51

Function: Testis-specific DNA binding protein responsible for insulator function, nuclear

architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin

modifiers. Plays a key role in gene imprinting in male germline, by participating in the

establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly

binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate

histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases

at these sites (By similarity). Seems to act as tumor suppressor

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for CTCFL

2 Interacting proteins for CTCFL (ENSP00000243914³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CREBZF	ENSP00000260058³	STRING (score=.779)
BRCA1	ENSP00000350283³	STRING (score=.7)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0045786	negative regulation of cell cycle	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CTCFL

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CTCFL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CTCFL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_080618

Sigma-Aldrich siRNA for CTCFL

Sigma-Aldrich shRNA for CTCFL

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_080618

REFSEQ mRNAs for CTCFL gene:

NM_080618.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_080618

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_080618
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_080618
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_080618

Additional cDNA sequence:

AF336042.1 AK128070.1 AK313990.1 AY071919.1 BC060763.1 BC130486.1 DQ294738.1 DQ778108.1

DQ778109.1 DQ778110.1 DQ778111.1 DQ778112.1 DQ778113.1 DQ778114.1 DQ778115.1 DQ778116.1

DQ778117.1 DQ778118.1 DQ778119.1 DQ778120.1 DQ778121.2 DQ778122.1 DQ778123.1 DQ778124.1

DQ778125.1 DQ778126.1 DQ778127.1 DQ778128.1 DQ778129.1 DQ778130.1 DQ778131.1

5 DOTS entries:

DT.101979256 DT.99957215 DT.303300 DT.100696089 DT.97768285

24/27 AceView cDNA sequences (see all 27 ):

AI024580 NM_080618 AY071919 BX094837 BX282332 BG527694 AL732020 BC060763

AL844306 AI024578 AK128070 AF336042 BG687495 BU170289 AL844477 BU629814

BG722482 AL049118 AL844304 AL844280 BQ429595 AL844410 BF209606 AW243377

highest scoring ESTs for CTCFL:

AF336042 AI024580 AK128070 AY071919 BC060763 AI024578 AL049118 AL844280 AL844304 AL844306

Unigene Cluster for CTCFL:

CCCTC-binding factor (zinc finger protein)-like

Hs.131543 [show with all ESTs]

Unigene Representative Sequence: DQ778119

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CTCFL

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b
SP1:
SP2:			-
SP3:

About this scheme

ECgene alternative splicing isoforms for CTCFL

2 Ensembl transcripts including schematic representations:

ENST00000371196 ENST00000243914

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CTCFL expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CTCFL

¹ / ² / ³

2 probe-sets matching CTCFL gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
66993_at²^{, 3}	U95-C	1	1.00	1.00	1.00	1.00	AI024580	0.80	1.00	0.91	1
1552368_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGCCCCTGTG

SOURCE GeneReport for Unigene cluster: Hs.131543
UniProtKB/Swiss-Prot: CTCFL_HUMAN, Q8NI51
Tissue specificity: Testis specific. Specifically expressed in primary spermatocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CTCFL gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CTCFL¹	--	CCCTC-binding factor (zinc finger protein)-like	81.67(n) 76.79(a)	477271 XM_534463.2 XP_534463.2
chimpanzee (Pan troglodytes)	CTCFL¹	--	CCCTC-binding factor (zinc finger protein)-like	98.64(n) 97.74(a)	458360 XM_514743.2 XP_514743.2
mouse (Mus musculus)	Ctcfl^{1, 5}	2⁵	CCCTC-binding factor (zinc finger protein)-like^{1, 5}	68.64(n)¹ 60.9(a)¹	664799¹ NM_001081387.1¹ NP_001074856.1¹ AL837509⁵ AL928599⁵ (see all 9)
sea squirt (Ciona intestinalis)	Cin.2315²	--	Ciona intestinalis cDNA, clonecitb042m20, full insert more	69.97(n)	AK116486.1

About this table Species with no ortholog for CTCFL

ENSEMBL Gene Tree for CTCFL

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CTCFL gene

CTCF² HINFP² ZFP64²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/219 NCBI SNPs in CTCFL are shown (see all 219 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 75)

AB	SNP ID	Valid	Chr 20 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs6070128^1,2	A,C,F,H	55532520(+)	`ACGCTC/GGGCCT`	1	E/Q	mis¹ ese³		8	EU EA WA	832
	rs6025606^1,2	A,C,F,H	55532139(+)	`TCCAGC/TAGTTT`	1	T/A	mis¹ ese³		8	EU EA WA	836
	rs8122634^1,2	C,F,H	55506388(+)	`TCTAGT/CATTTC`	1	--	ut3¹ ese³		7	EU EA WA NA	562
	rs6070122^1,2	C,F,H	55517169(+)	`CTTCTG/CTCGGA`	1	E/Q	mis¹ ese³		8	EU EA WA	836
	rs6092491^1,2	C,F,H	55521202(+)	`AGTTGC/TGCATA`	1	R/H	mis¹ ese³		4	EU EA WA	406
	rs7273099^1,2	F,H	55533848(+)	`AGGAGG/AGGAGG`	1	--	ng3¹ trp³		4	EU EA WA	418
	rs11699556^1,2	C,H	55506620(+)	`GACTAT/CTTTGA`	1	--	ut3¹		4	EU EA WA	420
	rs6025592^1,2	H	55505451(+)	`ggtcaG/Aatact`	1	--	ng5¹		4	EU EA WA	420
	rs2149285^1,2	H	55506318(+)	`CAAAAA/TTCTAA`	1	--	ut3¹ ese³		4	EU EA WA	416
	rs6070120^1,2	H	55506699(+)	`TTTGAG/AGTGTT`	1	--	ut3¹ ese³		4	EU EA WA	420

About this table

HapMap Linkage Disequilibrium images for CTCFL (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 607022

4 Novoseek disease relationships for CTCFL gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
testicular cancer	51.07	1	17363524 (1)
cancer	21.49	17	12191639 (3), 18095639 (2), 17363524 (2), 17962299 (2) (see all 6)
cancer lung	15.13	9	16140944 (5), 17260018 (3)
tumors	0.00	6	17062669 (2), 18095639 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/23 PubMed articles for CTCFL gene (see all 23 ):

The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. (PubMed id 12191639)^{1, 3, 4} Klenova E.M.... Lobanenkov V.V. (2002)
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. (PubMed id 12011441)^{1, 3, 4} Loukinov D.I.... Lobanenkov V.V. (2002)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{3, 4} Deloukas P....Rogers J. (2001)
BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours. (PubMed id 18195709)^{1, 3} D'Arcy V....Klenova E. (2008)
The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis. (PubMed id 17062669)^{1, 3} D'Arcy V....Klenova E. (2006)
DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. (PubMed id 18095639)^{1, 3} Woloszynska-Read A....Karpf A.R. (2007)
Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. (PubMed id 16140944)^{1, 3} Hong J.A....Schrump D.S. (2005)
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region. (PubMed id 18632606)^{1, 3} Nguyen P....Gius D. (2008)
Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors. (PubMed id 17962299)^{1, 3} Renaud S....Lobanenkov V. (2007)
Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression. (PubMed id 17363524)^{1, 3} Risinger J.I....Barrett J.C. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 140690	HGNC: 16234	AceView: CTCFL	Ensembl:ENSG00000124092	euGenes: HUgn140690
ECgene: CTCFL	H-InvDB: CTCFL

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for CTCFL
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CTCFL:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CTCFL-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CTCFL		Antibodies for CTCFL
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CTCFL		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CTCFL)
	Search for Antibodies
	Chimera RNAi (CTCFL)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (BORIS)
	Antibodies (BORIS)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for CTCFL

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CTCFL

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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CTCFL Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for CTCFL

Summaries
for CTCFL

Genomic Location
for CTCFL

Proteins
for CTCFL

Protein Domains/
Families
for CTCFL

Gene Function
for CTCFL

Pathways & Interactions
for CTCFL

Drugs & Compounds
for CTCFL

Transcripts
for CTCFL

Expression
for CTCFL

Orthologs
for CTCFL

Paralogs
for CTCFL

SNPs/Variants
for CTCFL

Disorders & Mutations
for CTCFL

Medical News
for CTCFL

Publications
for CTCFL

Search for CTCFL

Genome Databases showing CTCFL

Other Databases showing CTCFL

Specialized Databases showing CTCFL

Licensable Technologies
for CTCFL

Services
for CTCFL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CTCFL Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor CTCFL

Summariesfor CTCFL

Genomic Locationfor CTCFL

Proteinsfor CTCFL

Protein Domains/Familiesfor CTCFL

Gene Functionfor CTCFL

Pathways & Interactionsfor CTCFL

Drugs & Compoundsfor CTCFL

Transcriptsfor CTCFL

Expression for CTCFL

Orthologsfor CTCFL

Paralogsfor CTCFL

SNPs/Variantsfor CTCFL

Disorders & Mutationsfor CTCFL

Medical Newsfor CTCFL

Publicationsfor CTCFL

Search for CTCFL

Genome Databases showing CTCFL

Other Databases showing CTCFL

Specialized Databases showing CTCFL

Licensable Technologiesfor CTCFL

Servicesfor CTCFL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CTCFL

Summaries
for CTCFL

Genomic Location
for CTCFL

Proteins
for CTCFL

Protein Domains/
Families
for CTCFL

Gene Function
for CTCFL

Pathways & Interactions
for CTCFL

Drugs & Compounds
for CTCFL

Transcripts
for CTCFL

Expression
for CTCFL

Orthologs
for CTCFL

Paralogs
for CTCFL

SNPs/Variants
for CTCFL

Disorders & Mutations
for CTCFL

Medical News
for CTCFL

Publications
for CTCFL

Licensable Technologies
for CTCFL

Services
for CTCFL