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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CTC1 Gene

protein-coding GIFtS: 44
GCID: GC17M008161

CTS telomere maintenance complex component 1

(Previous names: tmp494178, chromosome 17 open reading frame 68 )
(Previous symbol: C17orf68)

Explore 6 diseases affiliated with
CTC1 via

MalaCards

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CTS Telomere Maintenance Complex Component 1¹ ²		AAF-132²
C17orf68¹ ² ³ ⁵		CRMCC²
AAF132¹ ² ⁵		Alpha Accessory Factor 132²
Tmp494178¹		Conserved Telomere Capping Protein 1²
HBV DNAPTP1-Transactivated Protein B² ³		CST Complex Subunit CTC1²
FLJ22170¹		Conserved Telomere Maintenance Component 1³
Chromosome 17 Open Reading Frame 68¹

External Ids:	HGNC: 26169¹	Entrez Gene: 80169²	Ensembl: ENSG00000178971⁷	OMIM: 613129⁵	UniProtKB: Q2NKJ3³

Export aliases for CTC1 gene to outside databases

Previous GC identifers: GC17M008139 GC17M008145 GC17M008149 GC17M008154

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CTC1:

This gene encodes a component of the CST complex. This complex plays an essential role in protecting telomeres from

degradation. This protein also forms a heterodimer with the CST complex subunit STN1 to form the enzyme alpha

accessory factor. This enzyme regulates DNA replication. Mutations in this gene are the cause of cerebroretinal

microangiopathy with calcifications and cysts. Alternate splicing results in both coding and non-coding variants.

(provided by RefSeq, Mar 2012)

UniProtKB/Swiss-Prot: CTC1_HUMAN, Q2NKJ3

Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect

telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent

manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST

complex has probably a more general role in DNA metabolism at non-telomeric sites

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010718.16

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for CTC1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for CTC1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTC1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1

CTC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTC1 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M008161: view genomic region (about GC identifiers)

Start:	8,128,139 bp from pter	End:	8,151,413 bp from pter
Size:	23,275 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CTC1_HUMAN, Q2NKJ3 (See protein sequence)

Recommended Name: CST complex subunit CTC1

Size: 1217 amino acids; 134609 Da

Subunit: Component of the CST complex, composed of TEN1/C17orf106, CTC1/C17orf68 and STN1/OBFC1. Interacts with

STN1/OBFC1; the interaction is direct

Subcellular location: Nucleus. Chromosome, telomere. Note=A transmembrane region is predicted by sequence analysis

tools (ESKW, MEMSAT and Phobius); however, given the telomeric localization of the protein, the relevance of the

transmembrane region is unsure in vivo

Sequence caution: Sequence=BAB15247.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=CAD38600.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: B3KR66 C9JEX5 Q1PCD1 Q2TBE3 Q8N3S6 Q9H6L0

Alternative splicing: 2 isoforms: Q2NKJ3-1 Q2NKJ3-2 (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for CTC1: NX_Q2NKJ3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q2NKJ3

CTC1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_079375.3

ENSEMBL proteins:

ENSP00000396018 ENSP00000313759 ENSP00000462720 ENSP00000462607 ENSP00000463230

Human Recombinant Protein Products:

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	Uscn Proteins for CTC1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000784	nuclear chromosome, telomeric region	IDA	19854130
GO:0005634	nucleus	ISS	--
GO:0070188	Stn1-Ten1 complex	ISS	--

CTC1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CTC1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q2NKJ3

UniProtKB/Swiss-Prot: CTC1_HUMAN, Q2NKJ3

Similarity: Belongs to the CTC1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CTC1_HUMAN, Q2NKJ3

Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect

telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent

manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST

complex has probably a more general role in DNA metabolism at non-telomeric sites

miRNA Products:		OriGene 3'-UTR Clone: CTC1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CTC1
		8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate CTC1 (see all 23):
		hsa-miR-4305 hsa-miR-29c hsa-miR-29a hsa-miR-3167 hsa-miR-124 hsa-miR-1538 hsa-miR-506 hsa-miR-362-5p

		SwitchGear 3'UTR luciferase reporter plasmid: CTC1 3' UTR sequence

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Gene Editing
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In Situ Assay
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003697	single-stranded DNA binding	ISS	--
GO:0005515	protein binding	IPI	19854130

CTC1 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for CTC1:

Synthetic lethal with Ras

Animal Models:
8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Ctc1):

cellular	growth/size	hematopoietic system	homeostasis/metabolism	immune system
integument	mortality/aging	no phenotypic analysis

CTC1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CTC1

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for CTC1 (ENSP00000313759⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
OBFC1	ENSP00000224950⁴	STRING: ENSP00000224950
POT1	ENSP00000350249⁴	STRING: ENSP00000350249
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000723	telomere maintenance	IMP	19854131
GO:0045740	positive regulation of DNA replication	ISS	--

CTC1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CTC1
Search CenterWatch for drugs/clinical trials and news about CTC1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CTC1 gene:

NM_025099.5

Unigene Cluster for CTC1:

CTS telomere maintenance complex component 1

Hs.156055 [show with all ESTs]

Unigene Representative Sequence: NM_025099

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000449476(uc002gkq.4 uc010cnv.3) ENST00000315684 ENST00000581729

ENST00000580299 ENST00000578441 ENST00000578537 ENST00000578240 ENST00000584439

ENST00000581967 ENST00000583254 ENST00000579066 ENST00000581671 ENST00000584842

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		hsa-miR-4305 hsa-miR-29c hsa-miR-29a hsa-miR-3167 hsa-miR-124 hsa-miR-1538 hsa-miR-506 hsa-miR-362-5p

		SwitchGear 3'UTR luciferase reporter plasmid: CTC1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CTC1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CTC1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Additional cDNA sequence:

AK025823.1 AK091077.1 AK225375.1 AK310636.1 BC026057.2 BC110373.1 BC111783.1 DQ451688.1

FJ790670.1 NR_046431.1

14 DOTS entries:

DT.407380 DT.425872 DT.100747230 DT.91894781 DT.92022394 DT.70102685 DT.91823027 DT.91680858

DT.92420329 DT.100716690 DT.100737391 DT.121005355 DT.121005392 DT.92420328

24/91 AceView cDNA sequences (see all 91):

BC026057 Z38218 AK025823 BM984769 CA426505 Z41923 AA971066 AA328784

AW665083 CK819040 BF001705 BF915066 BX444395 AA626584 AW613988 BG911027

BM127022 BM552583 BX452628 AI243332 BG686442 BG822205 AI917726 AI336988

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for CTC1 (see all 10) About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12a	·	12b	^	13a	·	13b	·	13c	^	14	^	15	^	16a	·	16b	^	17a	·
SP1:									-												-												-														-
SP2:									-				-								-												-														-
SP3:																																													-		-
SP4:
SP5:

ExUns:	17b	·	17c	^	18	^	19a	·	19b	^	20	^	21	^	22	^	23	^	24a	·	24b	·	24c	·	24d
SP1:			-
SP2:			-								-
SP3:			-
SP4:			-						-		-
SP5:

ECgene alternative splicing isoforms for CTC1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CTC1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGGCCGGG

About this image
See CTC1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CTC1

SOURCE GeneReport for Unigene cluster: Hs.156055

SABiosciences Custom PCR Arrays for CTC1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CTC1 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CTC1 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ctc1^{1 , 5}	RIKEN cDNA 1500010J02 gene⁵ CTS telomere maintenance complex component 1¹	76.94(n)¹ 69.42(a)¹		11 (42.29 cM)⁵ 68964¹ NM_001013256.2¹ NP_001013274.2¹ 69015911⁵
chicken (Gallus gallus)	Aves	CTC1¹	CTS telomere maintenance complex component 1	49.33(n) 39.4(a)		418324 XM_416547.3 XP_416547.3
lizard (Anolis carolinensis)	Reptilia	CTC1⁶	--	35(a)	1 ↔ 1	GL343473.1(552406-567627)
zebrafish (Danio rerio)	Actinopterygii	zgc:153125¹	zgc:153125	44.48(n) 32.48(a)		777638 NM_001077745.1 NP_001071213.1

ENSEMBL Gene Tree for CTC1 (if available)
TreeFam Gene Tree for CTC1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs199473676^1,2	C	pathogenic	8031327(-)	`GGACGG/TGAGAA`	3	G V	mis¹		0	--	--	--	--
rs8072663^1,2	C,F,A,H,	--	8023824(+)	`tccccC/Gctcca`	2	--	nc-transcript-variantut3¹		4		NS EA	408
rs8072826^1,2	A	--	8023893(+)	`caccaC/Tgcctg`	2	--	nc-transcript-variantut3¹		0	--	--	--	--
rs8072837^1,2	A	--	8023911(+)	`ttttgC/Tatttt`	2	--	nc-transcript-variantut3¹		0	--	--	--	--
rs8073526^1,2	A	--	8024004(+)	`cgcccA/Gccttg`	2	--	nc-transcript-variantut3¹		0	--	--	--	--
rs73975813^1,2	C,	--	8024231(+)	`CGTGGT/GCTCGG`	2	--	nc-transcript-variantut3¹		2		WA	120
rs115803038^1,2	C,F,	--	8024848(+)	`AGGTGG/AGCAGC`	2	--	nc-transcript-variantut3¹		1		WA	118
rs75503577^1,2	C,F,	--	8024993(+)	`GGCGAT/CCTCAT`	2	--	nc-transcript-variantut3¹		3		CSA NA	124
rs57270818^1,2	C,F,	--	8025074(+)	`GATATA/GAAAAC`	2	--	ut3¹ nc-transcript-variant		1		WA	118
rs11650309^1,2	C,F,H,	--	8025120(+)	`ACGCTG/CTTTCA`	2	--	nc-transcript-variantut3¹		24		NA NS EA WA	2900

HapMap Linkage Disequilibrium report for CTC1 (8128139 - 8151413 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CTC1: --
Human Gene Mutation Database (HGMD): CTC1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CTC1

DNA2.0 Custom Variant and Variant Library Synthesis for CTC1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CTC1 for disorders About GeneDecksing

OMIM gene information: 613129 OMIM disorders: --

UniProtKB/Swiss-Prot: CTC1_HUMAN, Q2NKJ3

Defects in CTC1 are the cause of cerebroretinal microangiopathy with calcifications and cysts (CRMCC)

[MIM:612199]. An autosomal recessive pleiomorphic disorder characterized primarily by intracranial calcifications,

leukodystrophy, and brain cysts. Affected individuals manifest a phenotype consistent with Coats plus syndrome or

Labrune syndrome. Coats plus syndrome patients have retinal telangiectasia and exudates as well as extraneurologic

manifestations, including osteopenia with poor bone healing and a high risk of gastrointestinal bleeding and portal

hypertension caused by vasculature ectasias in the stomach, small intestine, and liver. Some individuals with Coats

syndrome also have hair, skin, and nail changes, as well as anemia. Patients with Labrune syndrome do not have

extraneurologic manifestations

6 diseases for CTC1: About MalaCards

retinal telangiectasia portal hypertension leukodystrophy anemia

hypertension retinitis

Export disorders for CTC1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CTC1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with CTC1)

Utopia: connect your pdf to the dynamic
world of online information

RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to si ngle-stranded DNA and protects telomeres independently of the Pot1 pathway. (PubMed id 19854130)^{1, 2, 3} Miyake Y....Ishikawa F. (2009)
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes. (PubMed id 19854131)^{1, 2, 3} Surovtseva Y.V....Shippen D.E. (2009)
Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts. (PubMed id 22387016)^{1, 2} Polvi A.... Lehesjoki A.E. (2012)
Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus. (PubMed id 22267198)^{1, 2} Anderson B.H.... Crow Y.J. (2012)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The human CST complex is a terminator of telomerase ac tivity. (PubMed id 22763445)¹ Chen L.Y....Lingner J. (2012)
CTC1 Mutations in a patient with dyskeratosis congenit a. (PubMed id 22532422)¹ Keller R.B....Agarwal S. (2012)
Genomic determinants of motor and cognitive outcomes i n Parkinson's disease. (PubMed id 22658654)¹ Chung S.J....Maraganore D.M. (2012)
Human CST promotes telomere duplex replication and gen eral replication restart after fork stalling. (PubMed id 22863775)¹ Stewart J.A....Price C.M. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 80169	HGNC: 26169	AceView: FLJ22170	Ensembl:ENSG00000178971	euGenes: HUgn80169
ECgene: CTC1	H-InvDB: CTC1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CTC1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CTC1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CTC1 gene:
Search GeneIP for patents involving CTC1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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CTS telomere maintenance complex component 1

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