Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CTAGE8 Gene

Aliases for CTAGE8 Gene

  • CTAGE Family Member 8 2 3 5
  • CTAGE Family, Member 8 2
  • Protein CTAGE-8 4

External Ids for CTAGE8 Gene

Previous GeneCards Identifiers for CTAGE8 Gene

  • GC07U902615
  • GC07M143963

Summaries for CTAGE8 Gene

GeneCards Summary for CTAGE8 Gene

CTAGE8 (CTAGE Family Member 8) is a Protein Coding gene. An important paralog of this gene is CTAGE4.

Additional gene information for CTAGE8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTAGE8 Gene

Genomics for CTAGE8 Gene

Regulatory Elements for CTAGE8 Gene

Enhancers for CTAGE8 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H144833 1.1 ENCODE 11.7 -565.7 -565747 3.2 HDGF ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF766 CBX5 TPK1 CTAGE8 LOC154761 OR2A1 GC07M144690
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CTAGE8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CTAGE8 Gene

Genomic Locations for CTAGE8 Gene
3,111 bases
Minus strand

Genomic View for CTAGE8 Gene

Genes around CTAGE8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTAGE8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTAGE8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAGE8 Gene

Proteins for CTAGE8 Gene

  • Protein details for CTAGE8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    cTAGE family member 8
    Protein Accession:

    Protein attributes for CTAGE8 Gene

    777 amino acids
    Molecular mass:
    88077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CTAGE8 Gene

Post-translational modifications for CTAGE8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAGE8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTAGE8 Gene

Domains & Families for CTAGE8 Gene

Gene Families for CTAGE8 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CTAGE8 Gene


Suggested Antigen Peptide Sequences for CTAGE8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the cTAGE family.
  • Belongs to the cTAGE family.
genes like me logo Genes that share domains with CTAGE8: view

Function for CTAGE8 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTAGE8 Gene

Localization for CTAGE8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAGE8 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CTAGE8 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for CTAGE8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CTAGE8: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CTAGE8 Gene

Pathways & Interactions for CTAGE8 Gene

SuperPathways for CTAGE8 Gene

No Data Available

Interacting Proteins for CTAGE8 Gene

Gene Ontology (GO) - Biological Process for CTAGE8 Gene


No data available for Pathways by source and SIGNOR curated interactions for CTAGE8 Gene

Drugs & Compounds for CTAGE8 Gene

No Compound Related Data Available

Transcripts for CTAGE8 Gene

mRNA/cDNA for CTAGE8 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTAGE8 Gene

CTAGE family, member 8:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CTAGE8 Gene

No ASD Table

Relevant External Links for CTAGE8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CTAGE8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CTAGE8 Gene

mRNA differential expression in normal tissues according to GTEx for CTAGE8 Gene

This gene is overexpressed in Testis (x6.7), Thyroid (x4.5), Skin - Sun Exposed (Lower leg) (x4.3), and Skin - Not Sun Exposed (Suprapubic) (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CTAGE8 Gene

Protein tissue co-expression partners for CTAGE8 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CTAGE8 Gene:


SOURCE GeneReport for Unigene cluster for CTAGE8 Gene:


Evidence on tissue expression from TISSUES for CTAGE8 Gene

  • Liver(2.2)
genes like me logo Genes that share expression patterns with CTAGE8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CTAGE8 Gene

Orthologs for CTAGE8 Gene

This gene was present in the common ancestor of animals.

Orthologs for CTAGE8 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC470576 33
  • 94.7 (n)
(Bos Taurus)
Mammalia -- 34
  • 72 (a)
(Mus musculus)
Mammalia Ctage5 34
  • 66 (a)
(Canis familiaris)
Mammalia -- 34
  • 45 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 33 (a)
(Gallus gallus)
Aves -- 34
  • 30 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 31 (a)
(Danio rerio)
Actinopterygii ctage5 34
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta Tango1 34
  • 9 (a)
Species where no ortholog for CTAGE8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CTAGE8 Gene

Gene Tree for CTAGE8 (if available)
Gene Tree for CTAGE8 (if available)

Paralogs for CTAGE8 Gene

Paralogs for CTAGE8 Gene

(7) SIMAP similar genes for CTAGE8 Gene using alignment to 1 proteins: Pseudogenes for CTAGE8 Gene

genes like me logo Genes that share paralogs with CTAGE8: view

Variants for CTAGE8 Gene

Sequence variations from dbSNP and Humsavar for CTAGE8 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1006678756 -- 144,271,363(+) GGGGA(A/G)CTCCC intron-variant, upstream-variant-2KB
rs1007037239 -- 144,270,471(+) CTTTT(C/T)TGTAT intron-variant, upstream-variant-2KB
rs1011375967 -- 144,270,623(+) TGTTA(C/T)GGTAA intron-variant, upstream-variant-2KB
rs1011428469 -- 144,271,461(+) CATGT(C/G)GAACT intron-variant, upstream-variant-2KB
rs1018140529 -- 144,270,515(+) TGGAT(A/T)ATATG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CTAGE8 Gene

Variant ID Type Subtype PubMed ID
nsv981601 CNV duplication 23825009
nsv970956 CNV duplication 23825009
nsv970955 CNV duplication 23825009
nsv831176 CNV loss 17160897
nsv831175 CNV loss 17160897
nsv831174 CNV loss 17160897
nsv824360 CNV gain 20364138
nsv8227 CNV gain+loss 18304495
nsv821609 CNV duplication 20802225
nsv819701 CNV insertion 19587683
nsv7411 OTHER inversion 18451855
nsv608845 CNV loss 21841781
nsv608840 CNV loss 21841781
nsv608831 CNV loss 21841781
nsv608829 CNV loss 21841781
nsv608699 CNV gain 21841781
nsv515041 CNV gain 21397061
nsv510970 OTHER inversion 20534489
nsv508489 CNV deletion 20534489
nsv471646 CNV gain+loss 15918152
nsv469769 CNV gain+loss 16826518
nsv433394 CNV gain 18776910
nsv428188 CNV gain+loss 18775914
nsv1153905 CNV duplication 26484159
nsv1148453 CNV duplication 26484159
nsv1141559 CNV duplication 24896259
nsv1133019 OTHER inversion 24896259
nsv1119235 CNV duplication 24896259
nsv1119234 CNV duplication 24896259
nsv1032320 CNV gain 25217958
nsv1016831 CNV gain 25217958
esv8347 OTHER inversion 19470904
esv3891225 CNV gain 25118596
esv3584873 CNV loss 24956385
esv3432947 CNV duplication 20981092
esv3380478 CNV duplication 20981092
esv3379639 CNV duplication 20981092
esv3369041 CNV duplication 20981092
esv2759570 CNV gain+loss 17122850
esv24292 CNV gain+loss 19812545
esv1682998 OTHER inversion 17803354
esv1003295 OTHER inversion 20482838
dgv6744n100 CNV loss 25217958
dgv6743n100 CNV gain+loss 25217958
dgv6742n100 CNV loss 25217958
dgv6741n100 CNV loss 25217958
dgv6740n100 CNV loss 25217958
dgv6739n100 CNV gain+loss 25217958
dgv6738n100 CNV gain+loss 25217958
dgv6737n100 CNV gain 25217958
dgv6736n100 CNV gain 25217958
dgv6735n100 CNV gain 25217958
dgv6734n100 CNV gain+loss 25217958
dgv6733n100 CNV gain+loss 25217958
dgv6732n100 CNV gain+loss 25217958
dgv6731n100 CNV gain+loss 25217958
dgv6730n100 CNV loss 25217958
dgv6729n100 CNV gain 25217958
dgv6728n100 CNV gain+loss 25217958
dgv6727n100 CNV loss 25217958
dgv6726n100 CNV gain 25217958
dgv6725n100 CNV gain 25217958
dgv3972e59 CNV duplication 20981092
dgv3965e59 CNV duplication 20981092
dgv255n111 CNV deletion 26073780
dgv254n111 CNV duplication 26073780
dgv253n111 CNV duplication 26073780
dgv24n31 CNV gain 19718026
dgv152e203 CNV gain+loss 21179565
dgv11669n54 CNV loss 21841781
dgv11668n54 CNV gain 21841781

Relevant External Links for CTAGE8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CTAGE8 Gene

Disorders for CTAGE8 Gene

Relevant External Links for CTAGE8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CTAGE8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTAGE8 Gene

Publications for CTAGE8 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 3 4 60
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 60
  4. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 60

Products for CTAGE8 Gene

Sources for CTAGE8 Gene

Loading form....