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Aliases for CTAGE8 Gene

Aliases for CTAGE8 Gene

  • CTAGE Family Member 8 2 3 5
  • CTAGE Family, Member 8 2
  • Protein CTAGE-8 4

External Ids for CTAGE8 Gene

Previous GeneCards Identifiers for CTAGE8 Gene

  • GC07U902615
  • GC07M143963

Summaries for CTAGE8 Gene

GeneCards Summary for CTAGE8 Gene

CTAGE8 (CTAGE Family Member 8) is a Protein Coding gene. An important paralog of this gene is CTAGE4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTAGE8 Gene

Genomics for CTAGE8 Gene

Regulatory Elements for CTAGE8 Gene

Enhancers for CTAGE8 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F144833 1.2 ENCODE 11.9 -565.7 -565747 3.2 HDGF ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 TPK1 CTAGE8 LOC154761 OR2A1 GC07M144690
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CTAGE8 on UCSC Golden Path with GeneCards custom track

Genomic Location for CTAGE8 Gene

Chromosome:
7
Start:
144,266,674 bp from pter
End:
144,269,784 bp from pter
Size:
3,111 bases
Orientation:
Minus strand

Genomic View for CTAGE8 Gene

Genes around CTAGE8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTAGE8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTAGE8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAGE8 Gene

Proteins for CTAGE8 Gene

  • Protein details for CTAGE8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG41-CTGE8_HUMAN
    Recommended name:
    cTAGE family member 8
    Protein Accession:
    P0CG41

    Protein attributes for CTAGE8 Gene

    Size:
    777 amino acids
    Molecular mass:
    88077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CTAGE8 Gene

Post-translational modifications for CTAGE8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAGE8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTAGE8 Gene

Domains & Families for CTAGE8 Gene

Gene Families for CTAGE8 Gene

Protein Domains for CTAGE8 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CTAGE8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CG41

UniProtKB/Swiss-Prot:

CTGE8_HUMAN :
  • Belongs to the cTAGE family.
Family:
  • Belongs to the cTAGE family.
genes like me logo Genes that share domains with CTAGE8: view

Function for CTAGE8 Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTAGE8 Gene

Localization for CTAGE8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAGE8 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CTAGE8 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for CTAGE8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CTAGE8: view

Pathways & Interactions for CTAGE8 Gene

SuperPathways for CTAGE8 Gene

No Data Available

Interacting Proteins for CTAGE8 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000417289%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000417289 for CTAGE8 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CTAGE8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CTAGE8 Gene

Transcripts for CTAGE8 Gene

mRNA/cDNA for CTAGE8 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTAGE8 Gene

CTAGE family, member 8:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CTAGE8 Gene

No ASD Table

Relevant External Links for CTAGE8 Gene

GeneLoc Exon Structure for
CTAGE8
ECgene alternative splicing isoforms for
CTAGE8

Expression for CTAGE8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CTAGE8 Gene

mRNA differential expression in normal tissues according to GTEx for CTAGE8 Gene

This gene is overexpressed in Testis (x6.7), Thyroid (x4.5), Skin - Sun Exposed (Lower leg) (x4.3), and Skin - Not Sun Exposed (Suprapubic) (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CTAGE8 Gene



Protein tissue co-expression partners for CTAGE8 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CTAGE8 Gene:

CTAGE8

SOURCE GeneReport for Unigene cluster for CTAGE8 Gene:

Hs.661442
genes like me logo Genes that share expression patterns with CTAGE8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CTAGE8 Gene

Orthologs for CTAGE8 Gene

This gene was present in the common ancestor of animals.

Orthologs for CTAGE8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC470576 34
  • 94.7 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 72 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Ctage5 35
  • 66 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 45 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 34 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 30 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 31 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ctage5 35
  • 35 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Tango1 35
  • 9 (a)
OneToMany
Species where no ortholog for CTAGE8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CTAGE8 Gene

ENSEMBL:
Gene Tree for CTAGE8 (if available)
TreeFam:
Gene Tree for CTAGE8 (if available)

Paralogs for CTAGE8 Gene

(7) SIMAP similar genes for CTAGE8 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for CTAGE8 Gene

genes like me logo Genes that share paralogs with CTAGE8: view

Variants for CTAGE8 Gene

Sequence variations from dbSNP and Humsavar for CTAGE8 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs113068796 -- 144,271,719(+) AATAT(A/G)ATAAT intron-variant, upstream-variant-2KB
rs1635873 -- 144,267,174(+) AATAA(A/G)GCCAG intron-variant, reference, missense
rs1635875 -- 144,269,785(+) ACATA(C/T)AAGAA intron-variant, upstream-variant-2KB
rs199675416 -- 144,267,335(+) CTGCT(A/G)GTCCA intron-variant, reference, missense
rs200189416 -- 144,267,033(+) ATCCC(C/T)TGGTG intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CTAGE8 Gene

Variant ID Type Subtype PubMed ID
dgv11668n54 CNV gain 21841781
dgv11669n54 CNV loss 21841781
dgv152e203 CNV gain+loss 21179565
dgv24n31 CNV gain 19718026
dgv253n111 CNV duplication 26073780
dgv254n111 CNV duplication 26073780
dgv255n111 CNV deletion 26073780
dgv3965e59 CNV duplication 20981092
dgv3972e59 CNV duplication 20981092
dgv6725n100 CNV gain 25217958
dgv6726n100 CNV gain 25217958
dgv6727n100 CNV loss 25217958
dgv6728n100 CNV gain+loss 25217958
dgv6729n100 CNV gain 25217958
dgv6730n100 CNV loss 25217958
dgv6731n100 CNV gain+loss 25217958
dgv6732n100 CNV gain+loss 25217958
dgv6733n100 CNV gain+loss 25217958
dgv6734n100 CNV gain+loss 25217958
dgv6735n100 CNV gain 25217958
dgv6736n100 CNV gain 25217958
dgv6737n100 CNV gain 25217958
dgv6738n100 CNV gain+loss 25217958
dgv6739n100 CNV gain+loss 25217958
dgv6740n100 CNV loss 25217958
dgv6741n100 CNV loss 25217958
dgv6742n100 CNV loss 25217958
dgv6743n100 CNV gain+loss 25217958
dgv6744n100 CNV loss 25217958
esv1003295 OTHER inversion 20482838
esv1682998 OTHER inversion 17803354
esv24292 CNV gain+loss 19812545
esv2759570 CNV gain+loss 17122850
esv3369041 CNV duplication 20981092
esv3379639 CNV duplication 20981092
esv3380478 CNV duplication 20981092
esv3432947 CNV duplication 20981092
esv3584873 CNV loss 24956385
esv3891225 CNV gain 25118596
esv8347 OTHER inversion 19470904
nsv1016831 CNV gain 25217958
nsv1032320 CNV gain 25217958
nsv1119234 CNV duplication 24896259
nsv1119235 CNV duplication 24896259
nsv1133019 OTHER inversion 24896259
nsv1141559 CNV duplication 24896259
nsv1148453 CNV duplication 26484159
nsv1153905 CNV duplication 26484159
nsv428188 CNV gain+loss 18775914
nsv433394 CNV gain 18776910
nsv469769 CNV gain+loss 16826518
nsv471646 CNV gain+loss 15918152
nsv508489 CNV deletion 20534489
nsv510970 OTHER inversion 20534489
nsv515041 CNV gain 21397061
nsv608699 CNV gain 21841781
nsv608829 CNV loss 21841781
nsv608831 CNV loss 21841781
nsv608840 CNV loss 21841781
nsv608845 CNV loss 21841781
nsv7411 OTHER inversion 18451855
nsv819701 CNV insertion 19587683
nsv821609 CNV duplication 20802225
nsv8227 CNV gain+loss 18304495
nsv824360 CNV gain 20364138
nsv831174 CNV loss 17160897
nsv831175 CNV loss 17160897
nsv831176 CNV loss 17160897
nsv970955 CNV duplication 23825009
nsv970956 CNV duplication 23825009
nsv981601 CNV duplication 23825009

Relevant External Links for CTAGE8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CTAGE8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CTAGE8 Gene

Disorders for CTAGE8 Gene

Relevant External Links for CTAGE8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CTAGE8

No disorders were found for CTAGE8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTAGE8 Gene

Publications for CTAGE8 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 64
  3. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3 64

Products for CTAGE8 Gene

Sources for CTAGE8 Gene

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