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CTAGE5 Gene

protein-coding   GIFtS: 50
GCID: GC14P039734

CTAGE Family, Member 5

(Previous name: meningioma expressed antigen 6 (coiled-coil proline-rich))
(Previous symbols: MGEA, MGEA6)
  See CTAGE5-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CTAGE Family, Member 51 2     Protein CTAGE-52 3
MGEA61 2 3     MGEA112 3
MGEA1 2 5     CTAGE Family Member 52
MEA62 3 5     Cutaneous T-Cell Lymphoma-Associated Antigen 52
Meningioma Expressed Antigen 6 (Coiled-Coil Proline-Rich)1 2     MEA113
Meningioma-Expressed Antigen 6/112 3     

External Ids:    HGNC: 70571   Entrez Gene: 42532   Ensembl: ENSG000001505277   OMIM: 6021325   UniProtKB: O153203   

Export aliases for CTAGE5 gene to outside databases

Previous GC identifers: GC14P038804 GC14P019849


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CTAGE5 Gene:
The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several
other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript
variants encoding different isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for CTAGE5 Gene:
CTAGE5 (CTAGE family, member 5) is a protein-coding gene. Diseases associated with CTAGE5 include familial idiopathic basal ganglia calcification, and meningioma. GO annotations related to this gene include enzyme activator activity. An important paralog of this gene is CTAGE4.

UniProtKB/Swiss-Prot: CTGE5_HUMAN, O15320
Function: Tumor-associated antigen

Gene Wiki entry for CTAGE5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CTAGE5 gene promoter:
         Nkx3-1   Pbx1a   RREB-1   Nkx3-1 v1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CTAGE5 promoter sequence
   Search Chromatin IP Primers for CTAGE5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CTAGE5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q13.3   Ensembl cytogenetic band:  14q21.1   HGNC cytogenetic band: 14q21.1

CTAGE5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTAGE5 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P039734:  view genomic region     (about GC identifiers)

Start:
39,734,476 bp from pter      End:
39,856,156 bp from pter
Size:
121,681 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CTGE5_HUMAN, O15320 (See protein sequence)
Recommended Name: cTAGE family member 5  
Size: 804 amino acids; 90996 Da
Sequence caution: Sequence=AAB86589.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B3KRA6 B4DQS6 D3DSA6 G3XAC5 O00169 Q6MZN2 Q6P2R8 Q86TF6 Q8IX92 Q8IX93
Alternative splicing: 10 isoforms:  O15320-1   O15320-2   O15320-3   O15320-4   O15320-5   O15320-6   O15320-7   O15320-8   
O15320-9   O15320-10   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for CTAGE5: NX_O15320

Explore proteomics data for CTAGE5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CTAGE5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001234917.1  NP_001234918.1  NP_001234919.1  NP_005921.2  NP_976229.1  NP_976230.1  NP_976231.1  

    ENSEMBL proteins: 
     ENSP00000451164   ENSP00000452395   ENSP00000343897   ENSP00000450869   ENSP00000379468  
     ENSP00000280083   ENSP00000452562   ENSP00000343912   ENSP00000450449   ENSP00000339286  
     ENSP00000379462  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: O15320

    UniProtKB/Swiss-Prot: CTGE5_HUMAN, O15320
    Similarity: Belongs to the cTAGE family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CTGE5_HUMAN, O15320
    Function: Tumor-associated antigen

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008047enzyme activator activity TAS9356211
         
    Find genes that share ontologies with CTAGE5           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CTAGE5
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CTAGE5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CTAGE5

    miRNA
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    miRTarBase miRNAs that target CTAGE5:
    hsa-mir-155-5p (MIRT020581), hsa-mir-124-3p (MIRT022418)

    Block miRNA regulation of human, mouse, rat CTAGE5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CTAGE5 (see all 28):
    hsa-miR-100* hsa-miR-520d-5p hsa-miR-4251 hsa-miR-374a hsa-miR-885-5p hsa-miR-548a-3p hsa-miR-548g hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidCTAGE5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CTAGE5

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTAGE5

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAGE5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1
    nucleus1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CTAGE5
    Interactions:

        Search GeneGlobe Interaction Network for CTAGE5

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for CTAGE5 (O153201, 2, 3 ENSP000002800834) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005191, 2, 3, ENSP000003614234EBI-1050253,EBI-375543 MINT-8110191 I2D: score=3 STRING: ENSP00000361423
    ALBP027683, ENSP000002958974I2D: score=1 STRING: ENSP00000295897
    TRAF6Q9Y4K33I2D: score=1 
    GRB2ENSP000003390074STRING: ENSP00000339007
    JUNBENSP000003033154STRING: ENSP00000303315
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043085positive regulation of catalytic activity TAS9356211

    Find genes that share ontologies with CTAGE5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CTAGE5 (CTGE5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CTAGE5 gene (8 alternative transcripts): 
    NM_001247988.1  NM_001247989.1  NM_001247990.1  NM_005930.3  NM_203354.2  NM_203355.2  NM_203356.2  NM_203357.1  

    Unigene Cluster for CTAGE5:

    CTAGE family, member 5
    Hs.540038  [show with all ESTs]
    Unigene Representative Sequence: AF338234
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554392 ENST00000555716 ENST00000341749(uc010tqe.1) ENST00000557038
    ENST00000396165 ENST00000556990 ENST00000280083 ENST00000556148 ENST00000348007
    ENST00000553352(uc001wvj.4) ENST00000556593 ENST00000553383 ENST00000341502
    ENST00000396158(uc001wve.1 uc001wuy.4 uc001wuz.4 uc001wvc.4 uc001wva.4 uc001wvb.4 uc001wvf.4 uc001wvg.4 uc001wvi.4 uc001wvh.4 uc010amz.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CTAGE5 (see all 28):
    hsa-miR-100* hsa-miR-520d-5p hsa-miR-4251 hsa-miR-374a hsa-miR-885-5p hsa-miR-548a-3p hsa-miR-548g hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidCTAGE5 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CTAGE5
    Predesigned siRNA for gene silencing in human, mouse, rat CTAGE5
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): CTAGE5 (NM_203355)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CTAGE5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTAGE5
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CTAGE5
      QuantiTect SYBR Green Assays in human, mouse, rat CTAGE5
      QuantiFast Probe-based Assays in human, mouse, rat CTAGE5

    Additional mRNA sequence: 

    AB209528.1 AF338233.1 AF338234.1 AK055791.1 AK091252.1 AK298935.1 AK315254.1 AL832233.1 
    AL833415.1 BC029513.1 BC039017.1 BC051363.1 BC064355.1 BX640994.1 BX648014.1 L06522.1 
    U73682.1 U94780.1 

    21 DOTS entries:

    DT.97796772  DT.101984773  DT.75192188  DT.100812173  DT.100726957  DT.92031420  DT.99984468  DT.215437 
    DT.100863231  DT.100812169  DT.100806581  DT.91759744  DT.95085749  DT.100812166  DT.120783394  DT.95203482 
    DT.97836415  DT.120783396  DT.121333158  DT.95072090  DT.95083993 

    Selected AceView cDNA sequences (see all 175):

    BX390661 CR621236 AA121563 CR622313 BU751886 NM_203354 AK055791 AI800255 
    NM_203356 BC051363 CR610706 AA593770 CR594736 AW016379 AI610195 W88942 
    AI025505 CA419154 AI144313 AA069799 NM_203355 NM_203357 NM_005930 AI739291 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CTAGE5    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b
    SP1:                                -                                                                                                                           
    SP2:                                                                                                                                                            
    SP3:                                -                                                                                   -                                       
    SP4:                          -     -                                                                                   -                                       
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for CTAGE5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CTAGE5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTGGAGCTT
    CTAGE5 Expression
    About this image

    CTAGE5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CTAGE5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.540038

    UniProtKB/Swiss-Prot: CTGE5_HUMAN, O15320
    Tissue specificity: Isoform 5A is expressed only in testis (at the protein level). Other isoforms are expressed in
    several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform
    5B are expressed in cutaneous T-cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and
    melanoma. Isoform 5B, but not isoform 5A, is expressed in head and neck squamous cell carcinoma

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAGE5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CTAGE5 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ctage51 , 5 CTAGE family, member 51, 5 83.31(n)1
    78.43(a)1
      12 (26.01 cM)5
    2176151  NM_146034.31  NP_666146.31 
     591297205 
    chicken
    (Gallus gallus)
    Aves MIA21 melanoma inhibitory activity 2 70.56(n)
    63.77(a)
      423339  XM_004941776.1  XP_004941833.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    36(a)
    1 → many
    1(23887867-23944107)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.40852 Transcribed sequence with weak similarity to protein more 71.08(n)    AL900010.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc560472 hypothetical protein MGC56047 70.55(n)   393281  BC050489.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tango16
    Transport and Golgi organization 1
    10(a)
    1 → many
    2L(6649388-6654574)


    ENSEMBL Gene Tree for CTAGE5 (if available)
    TreeFam Gene Tree for CTAGE5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CTAGE5 gene
    CTAGE42  MIA22  CTAGE62  MIA32  CTAGE92  CTAGE12  ENSG000002589412  CTAGE82  
    11 SIMAP similar genes for CTAGE5 using alignment to 6 protein entries:     CTGE5_HUMAN (see all proteins):
    MIA2    CTAGE1    CTAGE3P    CTAGE15    CTAGE4    CTAGE8
    CTAGE9    CTAGE6    MIA3    MIA    OTOR

    Find genes that share paralogs with CTAGE5           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for CTAGE5 (see all 12)
    PGOHUM00000242800 PGOHUM00000239494 PGOHUM00000248439 PGOHUM00000244808 PGOHUM00000247440


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CTAGE5 (see all 2190)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs714356291,2
    C--19850960(+) CTGCA-/T/TT  
            
    TTTTT
    7 -- int11NA 2
    rs355034671,2
    C--19858200(+) AAAAA-/A/AT  
            
    TTTTT
    7 -- int11NA 2
    rs1811447291,2
    --19860822(+) TATATA/TTATAT 7 -- int10--------
    rs1856372581,2
    --19860824(+) TATATA/GTATAT 7 -- int10--------
    rs50298201,2
    C,A--19860838(+) TATATA/TTATAT 7 -- int10--------
    rs1457617871,2
    --19860854(+) TTTAAA/GGAGAT 7 -- int10--------
    rs1926461661,2
    --19868738(+) CCGGAC/TGGGGT 7 -- int10--------
    rs128805191,2
    --19868756(+) cgggcA/G/Tggggc 7 -- int10--------
    rs1899658981,2
    --19868762(+) GGGGCA/TGACCC 7 -- int10--------
    rs1814407071,2
    --19868770(+) ACCCCC/TCACCT 7 -- int10--------

    HapMap Linkage Disequilibrium report for CTAGE5 (39734476 - 39856156 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CTAGE5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1110364CNV Deletion17803354
    esv2748622CNV Deletion23290073
    nsv84573CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602132    OMIM disorders: --

    UniProtKB/Swiss-Prot: CTGE5_HUMAN, O15320
  • Note=Autoantibodies against CTAGE5 are present in several cancer types, including benign meningioma and
    cutaneous T-cell lymphoma (CTCL)

  • 2 diseases for CTAGE5:    
    About MalaCards
    familial idiopathic basal ganglia calcification    meningioma


    Find genes that share disorders with CTAGE5           About GenesLikeMe

    Genetic Association Database (GAD): CTAGE5

    Export disorders for CTAGE5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CTAGE5 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with CTAGE5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning and chromosomal mapping of a predicted coiled-coil proline-rich protein immunogenic in meningioma patients. (PubMed id 9356211)1, 2, 3 Heckel D.... Meese E. (Hum. Mol. Genet. 1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing. (PubMed id 12839582)1, 2 Usener D.... Eichmueller S. (J. Invest. Dermatol. 2003)
    5. Serological detection of cutaneous T-cell lymphoma-associated antigens. (PubMed id 11149944)1, 3 Eichmueller S....Schadendorf D. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    6. MGEA6 is tumor-specific overexpressed and frequently recognized by patient-serum antibodies. (PubMed id 11803467)1, 9 Comtesse N....Meese E. (Oncogene 2002)
    7. Analysis of the CTAGE5 P521A variation with the risk of familial idiopathic basal ganglia calcification in an Iranian population. (PubMed id 23054591)1 Saliminejad K....Khorram Khorshid H.R. (J. Mol. Neurosci. 2013)
    8. cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites. (PubMed id 21525241)1 Saito K....Katada T. (Mol. Biol. Cell 2011)
    9. Population and computational analysis of the MGEA6 P521A variation as a risk factor for familial idiopathic basal ganglia calcification (Fahr's disease). (PubMed id 20838928)1 Lemos R.R....Oliveira J.R. (J. Mol. Neurosci. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4253 HGNC: 7057 AceView: CTAGE5 Ensembl:ENSG00000150527 euGenes: HUgn4253
    ECgene: CTAGE5 H-InvDB: CTAGE5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CTAGE5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CTAGE5 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CTAGE5 gene:
    Search GeneIP for patents involving CTAGE5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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