Aliases for CTAGE5 Gene
External Ids for CTAGE5 Gene
Previous HGNC Symbols for CTAGE5 Gene
Previous GeneCards Identifiers for CTAGE5 Gene
The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for CTAGE5 Gene
CTAGE5 (CTAGE Family Member 5, ER Export Factor) is a Protein Coding gene. Diseases associated with CTAGE5 include Cutaneous T Cell Lymphoma and Lymphoma. Among its related pathways are Vesicle-mediated transport and Transport to the Golgi and subsequent modification. GO annotations related to this gene include enzyme activator activity. An important paralog of this gene is ENSG00000258941.
UniProtKB/Swiss-Prot for CTAGE5 Gene
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.