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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CTAGE15 Gene

protein-coding   GIFtS: 27
GCID: GC07P143301

CTAGE Family, Member 15

(Previous names: CTAGE family, member 15, pseudogene)
(Previous symbol: CTAGE15P)
  Search for CTAGE15
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CTAGE Family, Member 151 2     CTAGE6-like2
CTAGE15P1 2 3     cTAGE-152
CTAGE Family, Member 15, Pseudogene1 2     CTAGE Family Member 152
Protein CTAGE-152 3     

External Ids:    HGNC: 372951   Entrez Gene: 4412942   Ensembl: ENSG000001762277   UniProtKB: A4D2H03   

Export aliases for CTAGE15 gene to outside databases

Previous GC identifer: GC07P143294


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CTAGE15 Gene: 
CTAGE15 (CTAGE family, member 15) is a protein-coding gene. An important paralog of this gene is CTAGE6P.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CTAGE15
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CTAGE15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q35   Ensembl cytogenetic band:  7q35   HGNC cytogenetic band: 7q35

CTAGE15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTAGE15 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P143301:  view genomic region     (about GC identifiers)

Start:
143,268,819 bp from pter      End:
143,271,478 bp from pter
Size:
2,660 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 142,686,245-142,688,599     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CTGEF_HUMAN, A4D2H0 (See protein sequence)
Recommended Name: cTAGE family member 15  
Size: 777 amino acids; 87868 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: A6H8Z8

Explore the universe of human proteins at neXtProt for CTAGE15: NX_A4D2H0

CTAGE15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

REFSEQ proteins: NP_001008747.1  
Human Recombinant Protein Products for CTAGE15: 
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Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral to membrane IEA--

CTAGE15 for ontologies           About GeneDecksing



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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: A4D2H0

UniProtKB/Swiss-Prot: CTGEF_HUMAN, A4D2H0
Similarity: Belongs to the cTAGE family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Animal Models:
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTAGE15

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CTAGE15 (CTGEF)

Search CenterWatch for drugs/clinical trials and news about CTAGE15 / CTGEF

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CTAGE15 gene: 
NM_001008747.2  

Unigene Cluster for CTAGE15:

CTAGE family, member 15
Hs.450233  [show with all ESTs]
Unigene Representative Sequence: BC146818
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000447022(uc011kth.2)
miRNA
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Additional mRNA sequence: BC146818.1 

3 DOTS entries:

DT.121041512  DT.40284638  DT.121037337 

2 AceView cDNA sequences:

BG719803 BI461930 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CTAGE15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
CTAGE15 Expression
About this image


Genevestigator expression for CTAGE15

SOURCE GeneReport for Unigene cluster: Hs.450233
    SABiosciences Custom PCR Arrays for CTAGE15
Primer
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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAGE15

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and chimp.

Orthologs for CTAGE15 gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chimpanzee
(Pan troglodytes)
Mammalia LOC4705761 putative protein cTAGE-6-like 94.44(n)
89.15(a)
  470576  XM_003309297.2  XP_003309345.1 


ENSEMBL Gene Tree for CTAGE15 (if available)
TreeFam Gene Tree for CTAGE15 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CTAGE15 gene
CTAGE6P  CTAGE4  CTAGE9  
6 SIMAP similar genes for CTAGE15 using alignment to 1 protein entry:     CTGEF_HUMAN:
CTAGE6    CTAGE8    CTAGE4    CTAGE9    CTAGE5    CTAGE1

CTAGE15 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/30 SNPs in CTAGE15 are shown (see all 30)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1999790001,2
C--143268346(+) AGAAGA/GGTGTA 1 -- us2k10--------
rs29497111,2
C,F--143268422(+) taccaA/Gtacag 1 -- us2k14Minor allele frequency- G:0.31NA 130
rs29497121,2
C--143268433(+) GGCAGG/ACCAAA 1 -- us2k11Minor allele frequency- A:0.50NA 2
rs2010103091,2
F--143269952(+) ACAAAA/TCAAAG 2 T S mis11Minor allele frequency- T:0.02EU 167
rs1855079631,2
--143270107(+) CTCTAC/TAGGAA 2 Y syn10--------
rs2018374291,2
F--143270163(+) TTCTAG/AAGTGG 2 /K /R mis11Minor allele frequency- A:0.01EU 519
rs726115761,2
C,F--143270172(+) GGAAGG/AAAAGC 2 /E /G mis12Minor allele frequency- A:0.44CSA EU 484
rs3698138071,2
----143268922(+) GAGCCC/TGTGCT 2 P syn10--------
rs3729934521,2
----143268569(+) TTAATC/TATGAA 1 -- us2k10--------
rs1471691171,2
----143268504(+) GTATGC/TATATC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for CTAGE15 (143268819 - 143271478 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for CTAGE15: --
SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CTAGE15 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CTAGE15)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
  4. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 441294 HGNC: 37295 AceView: LOC441294 Ensembl:ENSG00000176227 euGenes: HUgn441294
ECgene: CTAGE15 H-InvDB: CTAGE15

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for CTAGE15 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for CTAGE15 gene:
Search GeneIP for patents involving CTAGE15

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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About This Section

 
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