Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CTAG2 Gene

protein-coding   GIFtS: 50
GCID: GC0XM153880

Cancer/Testis Antigen 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cancer/Testis Antigen 21 2     CAMEL2 5
CTL-Recognized Antigen On Melanoma1 2     LAGE13 5
LAGE-1a Protein1 2     Cancer/Testis Antigen Family 61
Autoimmunogenic Cancer/Testis Antigen NY-ESO-22 3     Member 2a1
Cancer/Testis Antigen 6.22 3     Member 2b1
L Antigen Family Member 12 3     CT6.2a2
CT22 3     CT6.2b2
CT6.22 3     LAGE2B2
ESO22 3     Cancer/Testis Antigen Family 6, Member 2a2
LAGE-12 3     Cancer/Testis Antigen Family 6, Member 2b2

External Ids:    HGNC: 24921   Entrez Gene: 308482   Ensembl: ENSG000001268907   OMIM: 3003965   UniProtKB: O756383   

Export aliases for CTAG2 gene to outside databases

Previous GC identifers: GC0XM147943 GC0XM150260 GC0XM151465 GC0XM152347 GC0XM153443 GC0XM153533 GC0XM142426


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CTAG2 Gene:
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens.
This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and
prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame
product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor
antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple
transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for CTAG2 Gene:
CTAG2 (cancer/testis antigen 2) is a protein-coding gene. Diseases associated with CTAG2 include testicular germ cell tumor, and melanoma. An important paralog of this gene is CTAG1A.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011681.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the CTAG2 gene promoter:
         Sp1   ATF-2   c-Jun   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCTAG2 promoter sequence
   Search Chromatin IP Primers for CTAG2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CTAG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

CTAG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTAG2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM153880:  view genomic region     (about GC identifiers)

Start:
153,880,246 bp from pter      End:
153,881,853 bp from pter
Size:
1,608 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CTAG2_HUMAN, O75638 (See protein sequence)
Recommended Name: Cancer/testis antigen 2  
Size: 210 amino acids; 21061 Da
Secondary accessions: O75637 Q0VIL6 Q14CD6 Q2Z1N4 Q9BU80 Q9UJ89 Q9Y479
Alternative splicing: 2 isoforms:  O75638-1   O75638-2   

Explore the universe of human proteins at neXtProt for CTAG2: NX_O75638

Explore proteomics data for CTAG2 at MOPED


See CTAG2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_066274.2  NP_758965.2  

ENSEMBL proteins: 
 ENSP00000247306   ENSP00000358598  

CTAG2 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for CTAG2
OriGene Protein Over-expression Lysate for CTAG2
OriGene MassSpec for CTAG2
OriGene Custom Protein Services for CTAG2
GenScript Custom Purified and Recombinant Proteins Services for CTAG2
Novus Biologicals CTAG2 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for CTAG2

CTAG2 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for CTAG2
Novus Biologicals CTAG2 Antibody
Abcam antibodies for CTAG2
Cloud-Clone Corp. Antibodies for CTAG2
Search ThermoFisher Antibodies for CTAG2
LSBio Antibodies in human, mouse, rat for CTAG2

CTAG2 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for CTAG2
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CTAG2
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for CTAG2
Cloud-Clone Corp. CLIAs for CTAG2


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
1 InterPro protein domain:
 IPR015419 EKC/KEOPS_Pcc1

Graphical View of Domain Structure for InterPro Entry O75638

ProtoNet protein and cluster: O75638

UniProtKB/Swiss-Prot: CTAG2_HUMAN, O75638
Similarity: Belongs to the CTAG/PCC1 family


CTAG2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
CTAG2 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CTAG2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CTAG2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CTAG2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CTAG2

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat CTAG2 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate CTAG2
SwitchGear 3'UTR luciferase reporter plasmidCTAG2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CTAG2
Predesigned siRNA for gene silencing in human, mouse, rat CTAG2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CTAG2

Clone
Products:
     
OriGene clones in human, mouse for CTAG2 (see all 9)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): CTAG2 (NM_172377)
Sino Biological Human cDNA Clone for CTAG2
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CTAG2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTAG2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CTAG2
Browse ESI BIO Cell Lines and PureStem Progenitors for CTAG2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAG2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytoskeleton4
cytosol2
extracellular2
nucleus1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005813centrosome IDA--

CTAG2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus




    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CTAG2
Interactions:

    Search GeneGlobe Interaction Network for CTAG2

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CTAG2 (ENSP000002473064) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
UBCENSP000003448184STRING: ENSP00000344818
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

CTAG2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CTAG2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for CTAG2 gene (2 alternative transcripts): 
NM_020994.4  NM_172377.4  

Unigene Cluster for CTAG2:

Cancer/testis antigen 2
Hs.87225  [show with all ESTs]
Unigene Representative Sequence: AJ223040
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000247306(uc004fmh.2 uc004fmi.2) ENST00000369585
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CTAG2 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate CTAG2
SwitchGear 3'UTR luciferase reporter plasmidCTAG2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CTAG2
Predesigned siRNA for gene silencing in human, mouse, rat CTAG2
Clone
Products:
     
OriGene clones in human, mouse for CTAG2 (see all 9)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): CTAG2 (NM_172377)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CTAG2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTAG2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CTAG2
OriGene qSTAR qPCR primer pairs in human, mouse for CTAG2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CTAG2
  QuantiTect SYBR Green Assays in human, mouse, rat CTAG2
  QuantiFast Probe-based Assays in human, mouse, rat CTAG2

Additional mRNA sequence: 

AJ012833.1 AJ012834.1 AJ012835.1 AJ223040.1 AJ223041.1 AY679088.1 AY679089.1 BC002833.2 
BC113998.1 BC128045.1 

2 DOTS entries:

DT.100018675  DT.121283813 

Selected AceView cDNA sequences (see all 28):

AJ012833 AJ223040 AJ223041 BM684237 AJ012835 BU629220 BX279602 AJ012834 
BM719406 NM_172377 NM_020994 BI861547 BG575764 BC002833 BI856831 BM797218 
CA424840 BE274123 BE410697 BE390259 BE276194 BE410952 BE391232 BE387918 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for CTAG2    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3
SP1:                        
SP2:                        


ECgene alternative splicing isoforms for CTAG2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

CTAG2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
CTAG2 Expression
About this image

CTAG2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CTAG2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.87225

UniProtKB/Swiss-Prot: CTAG2_HUMAN, O75638
Tissue specificity: Testis and very low level in placenta and in some uterus samples. Observed in 25-50% of tumor
samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers

    Custom PCR Arrays for CTAG2
Primer
Products:
OriGene qPCR primer pairs and template standards for CTAG2
OriGene qSTAR qPCR primer pairs in human, mouse for CTAG2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CTAG2
QuantiTect SYBR Green Assays in human, mouse, rat CTAG2
QuantiFast Probe-based Assays in human, mouse, rat CTAG2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAG2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for CTAG2 gene from Selected species (see all 4)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
zebrafish
(Danio rerio)
Actinopterygii CABZ01063556.16
Uncharacterized protein
23(a)
1 → many
10(44098873-44103318) ENSDARG00000086267
        Species with no ortholog for CTAG2

ENSEMBL Gene Tree for CTAG2 (if available)
TreeFam Gene Tree for CTAG2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for CTAG2 gene
CTAG1A2  LAGE32  CTAG1B2  
2 SIMAP similar genes for CTAG2 using alignment to 2 protein entries:     CTAG2_HUMAN (see all proteins):
CTAG1A    CTAG1B

CTAG2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for CTAG2 (see all 93)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr X posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs736411061,2
C,F--153748430(+) ATATGG/CTACTG 2 -- ds50011Minor allele frequency- C:0.00WA 2
rs20758971,2
C,F,H--153748604(-) GGTTGT/CAGGGG 2 -- ds50015Minor allele frequency- C:0.45EA NS NA 398
rs1906033411,2
--153748670(+) GACACA/GGAATC 2 -- ut310--------
rs1808017841,2
--153748685(+) CTCAGC/TTTTAT 2 -- ut310--------
rs2018032511,2
C--153748849(+) GGGAGC/GCTGAG 3 P A mis1 ut310--------
rs1435207161,2
C,F--153748900(+) CAGGGA/GAAGCT 3 P S mis1 ut311Minor allele frequency- G:0.00NA 4544
rs1441795801,2
C,F--153748937(+) TGCAGT/ATGGCG 3 /Q /H mis1 ut311Minor allele frequency- A:0.00NA 4544
rs1510658251,2
C,F--153748941(+) GTTGGC/TGGTGG 3 H R mis1 ut311Minor allele frequency- T:0.00NA 4544
rs1127806781,2
C--153748992(+) ATCACA/C/GTTAAA 4 N K int1 syn1 mis11CSA 1
rs1471244241,2
F--153749003(+) GGCGAC/TACCTC 3 I V int1 mis11Minor allele frequency- T:0.00NA 4540

HapMap Linkage Disequilibrium report for CTAG2 (153880246 - 153881853 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CTAG2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv518228CNV Gain19592680
esv33784CNV Gain+Loss17666407

Locus Specific Mutation Databases (LSDB): CTAG2

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CTAG2
DNA2.0 Custom Variant and Variant Library Synthesis for CTAG2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 300396    OMIM disorders: --

19 diseases for CTAG2:    
About MalaCards
testicular germ cell tumor    melanoma    multiple myeloma    cervical squamous cell carcinoma
germ cell tumors    prostate cancer    chondrosarcoma    breast cancer
prostatitis    myeloma    lung cancer    cervicitis
esophagitis    squamous cell carcinoma    pancreatic cancer    ovarian cancer
hepatocellular carcinoma    colorectal cancer    pancreatitis


CTAG2 for disorders           About GeneDecksing

6 Novoseek inferred disease relationships for CTAG2 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
melanoma 47.4 22 19651643 (3), 11120859 (3), 12538712 (3), 15623618 (2) (see all 8)
cancer 46.4 9 17899192 (3), 16187088 (2), 11531257 (1), 15623618 (1) (see all 6)
tumors 40.8 23 16187088 (2), 12538712 (2), 14522938 (2), 10399963 (1) (see all 15)
esophageal carcinoma 39.2 3 11531257 (2), 16438850 (1)
nsclc 29.1 3 15061963 (1), 16353146 (1), 16299236 (1)
metastasis 0 1 16091172 (1)

Genetic Association Database (GAD): CTAG2
Human Genome Epidemiology (HuGE) Navigator: CTAG2 (1 document)

Export disorders for CTAG2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for CTAG2 gene, integrated from 10 sources (see all 51):
(articles sorted by number of sources associating them with CTAG2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1. (PubMed id 10399963)1, 2, 3, 9 Aarnoudse C.A.... Schrier P.I. (Int. J. Cancer 1999)
  2. Identification and expression analysis of novel LAGE-1 alleles with single nucleotide polymorphisms in cancer patients. (PubMed id 17899192)1, 2, 4, 9 Shao Y....Zhao H.-T. (J. Cancer Res. Clin. Oncol. 2008)
  3. LAGE-1, a new gene with tumor specificity. (PubMed id 9626360)1, 2, 3 Lethe B.G.... Boon T. (Int. J. Cancer 1998)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. (PubMed id 11709543)1, 2 Aradhya S....Nelson D.L. (Hum. Mol. Genet. 2001)
  6. A new specific gene expression in squamous cell carcinoma of the esophagus detected using representational difference analysis and cDNA microarray. (PubMed id 16446548)1, 9 Kan T....Shimada Y. (Oncology 2006)
  7. CD4+ Th2 cell recognition of HLA-DR-restricted epitopes derived from CAMEL: a tumor antigen translated in an alternative open reading frame. (PubMed id 12538712)1, 9 Slager E.H....Griffioen M. (J. Immunol. 2003)
  8. NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer. (PubMed id 14522938)1, 9 Odunsi K....Old L.J. (Cancer Res. 2003)
  9. Efficient simultaneous presentation of NY-ESO-1/LAGE-1 primary and nonprimary open reading frame-derived CTL epitopes in melanoma. (PubMed id 11120859)1, 9 Rimoldi D....Valmori D. (J. Immunol. 2000)
  10. Identification of multiple HLA-DR-restricted epitopes of the tumor-associated antigen CAMEL by CD4+ Th1/Th2 lymphocytes. (PubMed id 15067093)1, 9 Slager E.H....Osanto S. (J. Immunol. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 30848 HGNC: 2492 AceView: CTAG2 Ensembl:ENSG00000126890 euGenes: HUgn30848
ECgene: CTAG2 H-InvDB: CTAG2

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for CTAG2 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CTAG2 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for CTAG2 gene:
Search GeneIP for patents involving CTAG2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CTAG2  
 OriGene qPCR primer pairs and template standards for CTAG2   OriGene Protein Over-expression Lysate for CTAG2  
 OriGene MassSpec something-or-other for CTAG2   OriGene clones in human, mouse for CTAG2  
 OriGene qSTAR qPCR primer pairs in human, mouse for CTAG2   OriGene Purified Protein for CTAG2  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CTAG2   OriGene Custom Protein Services for CTAG2  

 
 
 Block miRNA regulation of human, mouse, rat CTAG2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CTAG2
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CTAG2 Predesigned siRNA for gene silencing in human, mouse, rat CTAG2
 QuantiFast Probe-based Assays in human, mouse, rat CTAG2 QuantiTect SYBR Green Assays in human, mouse, rat CTAG2
 Custom PCR Arrays for CTAG2 Search Chromatin IP Primers for CTAG2
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CTAG2  Search GeneGlobe Interaction Network for CTAG2
 Regulatory tfbs in CTAG2 promoter
 GenScript Custom Purified and Recombinant Proteins Services for CTAG2 GenScript cDNA clones with any tag delivered in your preferred vector for CTAG2
 GenScript Custom Assay Services for CTAG2 GenScript Custom overexpressing Cell Line Services for CTAG2
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for CTAG2
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 cDNA Clones for CTAG2
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 CTAG2 antibodies
 CTAG2 lysates
 Antibodies for CTAG2
 See all of Abcam's Antibodies, Kits and Proteins for CTAG2
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for CTAG2
 Antibodies for CTAG2
 ELISAs for CTAG2
 CLIAs for CTAG2



 Browse ESI BIO Cell Lines and PureStem Progenitors for CTAG2
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CTAG2
 SwitchGear 3'UTR luciferase reporter plasmids for CTAG2
 SwitchGear Promoter luciferase reporter plasmids for CTAG2
 Search ThermoFisher Antibodies for CTAG2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CTAG2
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CTAG2
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CTAG2
 LSBio Antibodies in human, mouse, rat for CTAG2
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      CTAG2 gene at Home site.
Version: 3.12.142 28 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4