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Aliases for CTAG1A Gene

Aliases for CTAG1A Gene

  • Cancer/Testis Antigen 1A 2 3
  • LAGE2A 3 4 6
  • Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 3 4
  • Cancer/Testis Antigen 6.1 3 4
  • L Antigen Family Member 2 3 4
  • LAGE-2 3 4
  • CT6.1 3 4
  • ESO1 3 4
  • Cancer/Testis Antigen 1-A 3
  • Cancer/Testis Antigen 1 3
  • CTAG1A CTAG1B 4
  • LAGE2B 4
  • CTAG1 4
  • LAGE2 4
  • CTAG 4

External Ids for CTAG1A Gene

Summaries for CTAG1A Gene

Entrez Gene Summary for CTAG1A Gene

  • CTAG1A is an identical copy of the CTAG1B gene (MIM 300156) (Aradhya et al., 2001 [PubMed 11709543]).[supplied by OMIM, Mar 2008]

GeneCards Summary for CTAG1A Gene

CTAG1A (Cancer/Testis Antigen 1A) is a Protein Coding gene. An important paralog of this gene is CTAG1B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTAG1A Gene

Genomics for CTAG1A Gene

Genomic Location for CTAG1A Gene

Start:
154,585,143 bp from pter
End:
154,586,821 bp from pter
Size:
1,679 bases
Orientation:
Plus strand

Genomic View for CTAG1A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CTAG1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAG1A Gene

Regulatory Elements for CTAG1A Gene

Proteins for CTAG1A Gene

  • Protein details for CTAG1A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P78358-CTG1B_HUMAN
    Recommended name:
    Cancer/testis antigen 1
    Protein Accession:
    P78358
    Secondary Accessions:
    • A1L417
    • B7WNL9
    • Q7LBY4
    • Q9NY13

    Protein attributes for CTAG1A Gene

    Size:
    180 amino acids
    Molecular mass:
    17992 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for CTAG1A Gene

    Alternative splice isoforms for CTAG1A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CTAG1A Gene

Proteomics data for CTAG1A Gene at MOPED

Post-translational modifications for CTAG1A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAG1A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTAG1A Gene

Domains for CTAG1A Gene

Protein Domains for CTAG1A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CTG1B_HUMAN
Family:
  • Belongs to the CTAG/PCC1 family.:
    • P78358
genes like me logo Genes that share domains with CTAG1A: view

No data available for Gene Families for CTAG1A Gene

Function for CTAG1A Gene

Gene Ontology (GO) - Molecular Function for CTAG1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 17137291
genes like me logo Genes that share ontologies with CTAG1A: view

Phenotypes for CTAG1A Gene

GenomeRNAi human phenotypes for CTAG1A:
genes like me logo Genes that share phenotypes with CTAG1A: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CTAG1A Gene

Localization for CTAG1A Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAG1A Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CTAG1A Gene COMPARTMENTS Subcellular localization image for CTAG1A gene
Compartment Confidence
cytosol 2
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CTAG1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with CTAG1A: view

Pathways for CTAG1A Gene

SuperPathways for CTAG1A Gene

No Data Available

Interacting Proteins for CTAG1A Gene

Gene Ontology (GO) - Biological Process for CTAG1A Gene

None

No data available for Pathways by source for CTAG1A Gene

Transcripts for CTAG1A Gene

mRNA/cDNA for CTAG1A Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTAG1A Gene

Cancer/testis antigen 1A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CTAG1A Gene

No ASD Table

Relevant External Links for CTAG1A Gene

GeneLoc Exon Structure for
CTAG1A
ECgene alternative splicing isoforms for
CTAG1A

Expression for CTAG1A Gene

mRNA expression in normal human tissues for CTAG1A Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CTAG1A Gene

SOURCE GeneReport for Unigene cluster for CTAG1A Gene Hs.534310

mRNA Expression by UniProt/SwissProt for CTAG1A Gene

P78358-CTG1B_HUMAN
Tissue specificity: Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).
genes like me logo Genes that share expressions with CTAG1A: view

Orthologs for CTAG1A Gene

Evolution for CTAG1A Gene

ENSEMBL:
Gene Tree for CTAG1A (if available)
TreeFam:
Gene Tree for CTAG1A (if available)

No data available for Orthologs for CTAG1A Gene

Paralogs for CTAG1A Gene

Paralogs for CTAG1A Gene

Selected SIMAP similar genes for CTAG1A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CTAG1A: view

Variants for CTAG1A Gene

Sequence variations from dbSNP and Humsavar for CTAG1A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs112926777 -- 154,583,392(+) TGTCT(C/T)CCTGC upstream-variant-2KB
rs200099747 -- 154,586,534(+) ACTGA(C/T)TGCTG reference, missense
rs200533109 -- 154,586,183(+) CCATG(A/G)AAGCA missense, reference

Structural Variations from Database of Genomic Variants (DGV) for CTAG1A Gene

Variant ID Type Subtype PubMed ID
esv33199 CNV Gain+Loss 17666407
esv33784 CNV Gain+Loss 17666407
nsv519042 CNV Gain 19592680
nsv508816 CNV Insertion 20534489
nsv7469 OTHER Inversion 18451855
esv29893 CNV Gain 19812545
nsv518228 CNV Gain 19592680
esv27930 CNV Gain 19812545

Relevant External Links for CTAG1A Gene

HapMap Linkage Disequilibrium report
CTAG1A

Disorders for CTAG1A Gene

No disorders were found for CTAG1A Gene.

No data available for UniProtKB/Swiss-Prot for CTAG1A Gene

Publications for CTAG1A Gene

  1. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. (PMID: 10523621) De Smet C. … Boon T. (Mol. Cell. Biol. 1999) 2 3 4
  2. Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. (PMID: 11709543) Aradhya S. … Nelson D.L. (Hum. Mol. Genet. 2001) 2 3 4
  3. The cancer-testis gene, NY-ESO-1, is expressed in normal fetal and adult testes and in spermatocytic seminomas and testicular carcinoma in situ. (PMID: 12065688) Satie A.P. … Samson M. (Lab. Invest. 2002) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4

Products for CTAG1A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CTAG1A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CTAG1A
    • Block miRNA regulation of CTAG1A using miScript Target Protectors

    Sources for CTAG1A Gene

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