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Aliases for CTAG1A Gene

Aliases for CTAG1A Gene

  • Cancer/Testis Antigen 1A 2 3
  • Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 3 4
  • Cancer/Testis Antigen 6.1 3 4
  • L Antigen Family Member 2 3 4
  • LAGE-2 3 4
  • LAGE2A 3 4
  • CT6.1 3 4
  • ESO1 3 4
  • Cancer/Testis Antigen 1-A 3
  • CTAG1A CTAG1B 4
  • LAGE2B 4
  • CTAG1 4
  • LAGE2 4
  • CTAG 4

External Ids for CTAG1A Gene

Previous GeneCards Identifiers for CTAG1A Gene

  • GC0XP152283
  • GC0XM153409
  • GC0XM153500
  • GC0XP153467
  • GC0XP153813

Summaries for CTAG1A Gene

Entrez Gene Summary for CTAG1A Gene

  • CTAG1A is an identical copy of the CTAG1B gene (MIM 300156) (Aradhya et al., 2001 [PubMed 11709543]).[supplied by OMIM, Mar 2008]

GeneCards Summary for CTAG1A Gene

CTAG1A (Cancer/Testis Antigen 1A) is a Protein Coding gene. An important paralog of this gene is CTAG1B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTAG1A Gene

Genomics for CTAG1A Gene

Regulatory Elements for CTAG1A Gene

Genomic Location for CTAG1A Gene

Chromosome:
X
Start:
154,585,143 bp from pter
End:
154,586,821 bp from pter
Size:
1,679 bases
Orientation:
Plus strand

Genomic View for CTAG1A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CTAG1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAG1A Gene

Proteins for CTAG1A Gene

  • Protein details for CTAG1A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P78358-CTG1B_HUMAN
    Recommended name:
    Cancer/testis antigen 1
    Protein Accession:
    P78358
    Secondary Accessions:
    • A1L417
    • B7WNL9
    • Q7LBY4
    • Q9NY13

    Protein attributes for CTAG1A Gene

    Size:
    180 amino acids
    Molecular mass:
    17992 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for CTAG1A Gene

    Alternative splice isoforms for CTAG1A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CTAG1A Gene

Proteomics data for CTAG1A Gene at MOPED

Post-translational modifications for CTAG1A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAG1A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for CTAG1A Gene

Domains & Families for CTAG1A Gene

Protein Domains for CTAG1A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P78358

UniProtKB/Swiss-Prot:

CTG1B_HUMAN :
  • Belongs to the CTAG/PCC1 family.
Family:
  • Belongs to the CTAG/PCC1 family.
genes like me logo Genes that share domains with CTAG1A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CTAG1A Gene

Function for CTAG1A Gene

Gene Ontology (GO) - Molecular Function for CTAG1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 17137291
genes like me logo Genes that share ontologies with CTAG1A: view

Phenotypes for CTAG1A Gene

GenomeRNAi human phenotypes for CTAG1A:
genes like me logo Genes that share phenotypes with CTAG1A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CTAG1A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTAG1A Gene

Localization for CTAG1A Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAG1A Gene

Gene Ontology (GO) - Cellular Components for CTAG1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with CTAG1A: view

No data available for Subcellular locations from COMPARTMENTS for CTAG1A Gene

Pathways & Interactions for CTAG1A Gene

SuperPathways for CTAG1A Gene

No Data Available

Interacting Proteins for CTAG1A Gene

Gene Ontology (GO) - Biological Process for CTAG1A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CTAG1A Gene

Drugs & Compounds for CTAG1A Gene

No Compound Related Data Available

Transcripts for CTAG1A Gene

mRNA/cDNA for CTAG1A Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTAG1A Gene

Cancer/testis antigen 1A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CTAG1A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CTAG1A Gene

No ASD Table

Relevant External Links for CTAG1A Gene

GeneLoc Exon Structure for
CTAG1A
ECgene alternative splicing isoforms for
CTAG1A

Expression for CTAG1A Gene

mRNA expression in normal human tissues for CTAG1A Gene

Protein differential expression in normal tissues from HIPED for CTAG1A Gene

This gene is overexpressed in Bone (43.6), Liver, secretome (12.1), and Testis (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CTAG1A Gene



SOURCE GeneReport for Unigene cluster for CTAG1A Gene Hs.534310

mRNA Expression by UniProt/SwissProt for CTAG1A Gene

P78358-CTG1B_HUMAN
Tissue specificity: Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).
genes like me logo Genes that share expression patterns with CTAG1A: view

Protein tissue co-expression partners for CTAG1A Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CTAG1A Gene

Orthologs for CTAG1A Gene

Evolution for CTAG1A Gene

ENSEMBL:
Gene Tree for CTAG1A (if available)
TreeFam:
Gene Tree for CTAG1A (if available)

No data available for Orthologs for CTAG1A Gene

Paralogs for CTAG1A Gene

Paralogs for CTAG1A Gene

(2) SIMAP similar genes for CTAG1A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CTAG1A: view

Variants for CTAG1A Gene

Sequence variations from dbSNP and Humsavar for CTAG1A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs112926777 -- 154,583,392(+) TGTCT(C/T)CCTGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CTAG1A Gene

Variant ID Type Subtype PubMed ID
esv33199 CNV Gain+Loss 17666407
esv33784 CNV Gain+Loss 17666407
nsv519042 CNV Gain 19592680
nsv508816 CNV Insertion 20534489
nsv7469 OTHER Inversion 18451855
esv29893 CNV Gain 19812545
nsv518228 CNV Gain 19592680
esv27930 CNV Gain 19812545

Relevant External Links for CTAG1A Gene

HapMap Linkage Disequilibrium report
CTAG1A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CTAG1A Gene

Disorders for CTAG1A Gene

Relevant External Links for CTAG1A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CTAG1A
genes like me logo Genes that share disorders with CTAG1A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTAG1A Gene

Publications for CTAG1A Gene

  1. Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. (PMID: 11709543) Aradhya S. … Nelson D.L. (Hum. Mol. Genet. 2001) 2 67
  2. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. (PMID: 10523621) De Smet C. … Boon T. (Mol. Cell. Biol. 1999) 2 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6). (PMID: 17137291) Cho H.J. … Simpson A.J. (Cancer Immun. 2006) 67
  5. Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance. (PMID: 16596224) Yoshida N. … Nishimura T. (Int. J. Oncol. 2006) 67

Products for CTAG1A Gene

Sources for CTAG1A Gene

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